phosphorylated moderate kinase activity BRAF mutants [plasma membrane]

Stable Identifier
R-HSA-8936658
Type
Set [CandidateSet]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Literature References
PubMed ID Title Journal Year
16474404 Germline KRAS and BRAF mutations in cardio-facio-cutaneous syndrome

Cavé, H, Aoki, Y, Heron, D, Kure, S, Matsubara, Y, Hennekam, RC, Baumann, C, Naritomi, K, Gillessen-Kaesbach, G, Matsumoto, N, Bonneau, D, Kurosawa, K, Ohashi, H, Narumi, Y, Neri, G, Kavamura, MI, Kaname, T, Wilson, L, Verloes, A, Niihori, T, Wieczorek, D, Okamoto, N, Kato, K, Corona, G

Nat. Genet. 2006
12068308 Mutations of the BRAF gene in human cancer

Maitland, N, Jayatilake, H, Futreal, PA, Yuen, ST, Marshall, CJ, Menzies, A, Parker, A, Chenevix-Trench, G, Leung, SY, Garnett, MJ, Davis, N, Shipley, J, Cooper, C, Darrow, TL, Marais, R, Paterson, H, Palmieri, G, Floyd, Y, Bottomley, W, Bigner, DD, Bignell, GR, Stevens, C, Cossu, A, Hall, S, Ho, JW, Wilson, R, Mould, C, Gusterson, BA, Watt, S, Cox, C, Riggins, GJ, Flanagan, A, Gray, K, Wooster, R, Hooper, S, Teague, J, Ewing, R, Edkins, S, Seigler, HF, Hargrave, D, Hawes, R, Kosmidou, V, Nicholson, A, Stephens, P, Weber, BL, Hughes, J, Davies, H, Woffendin, H, Stratton, MR, Clegg, S, Dicks, E, Pritchard-Jones, K

Nature 2002
15035987 Mechanism of activation of the RAF-ERK signaling pathway by oncogenic mutations of B-RAF

Niculescu-Duvaz, D, Lee, S, Marais, R, Marshall, CJ, Barford, D, Jones, CM, Good, VM, Springer, CJ, Wan, PT, Garnett, MJ, Roe, SM

Cell 2004
Participants
Participates
Disease
Name Identifier Synonyms
cardiofaciocutaneous syndrome DOID:0060233 CFC syndrome, cardio-facial-cutaneous syndrome
cancer DOID:162 malignant tumor, malignant neoplasm, primary cancer
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