Ub-C85-UBE2D1 [nucleoplasm]

Stable Identifier
R-HSA-8937534
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
UbcH5/Ubc4
Icon
Ub-C85-UBE2D1 [nucleoplasm] icon
Ub-C85-UBE2D1 [nucleoplasm] icon
Locations in the PathwayBrowser
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Literature References
PubMed ID Title Journal Year
26502057 Systematic E2 screening reveals a UBE2D-RNF138-CtIP axis promoting DNA repair

Schmidt, CK, Galanty, Y, Sczaniecka-Clift, M, Coates, J, Jhujh, S, Demir, M, Cornwell, M, Beli, P, Jackson, SP

Nat. Cell Biol. 2015
External Reference Information
External Reference
UniProt:P51668 UBE2D1
Gene Names
UBE2D1, SFT, UBC5A, UBCH5, UBCH5A
Chain
chain:1-147
Reference Genes
BioGPS Gene:7321 UBE2D1
COSMIC (genes):UBE2D1 UBE2D1
CTD Gene:7321 UBE2D1
dbSNP Gene:7321 UBE2D1
ENSEMBL:ENSG00000072401 UBE2D1
HGNC:12474 UBE2D1
KEGG:hsa:7321 UBE2D1
Monarch:7321 UBE2D1
NCBI Gene:7321 UBE2D1
OMIM:602961 UBE2D1
UCSC:P51668 UBE2D1
Reference Transcript
Other Identifiers
1164_at
11723042_at
11723043_at
16705064
211764_PM_s_at
211764_s_at
214590_PM_s_at
214590_s_at
3247758
3247764
3247765
3247766
3247767
3247768
3247769
3247771
3247772
3247773
3247774
3247775
37826_at
7321
7927658
A_24_P13032
A_24_P364025
GE79396
GO:0000122
GO:0000166
GO:0000209
GO:0003824
GO:0004842
GO:0005515
GO:0005524
GO:0005634
GO:0005654
GO:0005737
GO:0005829
GO:0006355
GO:0006511
GO:0016567
GO:0016740
GO:0030163
GO:0030514
GO:0031398
GO:0031669
GO:0032991
GO:0038202
GO:0043161
GO:0061630
GO:0061631
GO:0070936
GO:0140096
GO:1902916
GO:1904262
HMNXSV003032080
Hs.318435.0.S2_3p_s_at
ILMN_1787988
PH_hs_0007586
TC10000360.hg
g13543662_3p_s_at
Participates
as a component of
Other forms of this molecule
UBE2D1 [cytosol]
UBE2D1 [nucleoplasm]
Ub-C85-UBE2D1 [cytosol]
Modified Residues
Name
S-(glycyl)-L-cysteine (Cys-Gly) at 85
Coordinate
85
PsiMod Name
S-(glycyl)-L-cysteine (Cys-Gly)
PsiMod Definition
A protein modification that effectively crosslinks an L-cysteine residue and a glycine residue by a thioester bond to form S-glycyl-L-cysteine.
Cross References
RefSeq
Guide to Pharmacology - Targets
OpenTargets
ENSEMBL
IntEnz
GeneCards
HPA
PRO
Pharos - Targets
HMDB Protein
PDB
Interactors (50)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:Q96FW1 OTUB1  2 0.851 15
 UniProt:Q9Y4L5 RNF115  1 0.83 12
 UniProt:Q9BV68 RNF126  1 0.817 7
 UniProt:Q96BH1 RNF25  1 0.801 6
 UniProt:Q9HCM9 TRIM39  1 0.8 6
 UniProt:Q99942 RNF5  1 0.795 10
 UniProt:Q8ND25 ZNRF1  1 0.788 9
 UniProt:Q9Y3C5 RNF11      0.788 9
 UniProt:P98170 XIAP  3 0.782 6
 UniProt:Q86UW9 DTX2  1 0.781 7
 UniProt:O15344 MID1  1 0.781 7
 UniProt:Q6ZNA4 RNF111  2 0.742 5
 UniProt:Q9H000 MKRN2      0.718 6
 UniProt:Q9UJV3-2 MID2      0.718 6
 UniProt:Q9P0P0 RNF181  1 0.666 4
 UniProt:Q9BZR9 TRIM8  1 0.666 4
 UniProt:Q06587 RING1  1 0.666 6
 UniProt:Q99496 RNF2  1 0.666 4
 UniProt:Q8N9I9 DTX3      0.666 6
 UniProt:Q9UBS8 RNF14  1 0.666 4
 UniProt:Q96GF1 RNF185  1 0.666 4
 UniProt:Q13064 MKRN3      0.666 4
 IntAct:EBI-4399559 UBIQ      0.623 3
 UniProt:Q9Y508 RNF114  1 0.621 3
 UniProt:Q8N5U6 RNF10      0.621 3
 UniProt:Q9CZW6  1 0.558 2
 UniProt:P62990 UBIQ      0.558 2
 UniProt:Q9HCM9-2 TRIM39      0.556 5
 UniProt:O75382 TRIM3  1 0.556 3
 UniProt:Q96EP1-2 CHFR      0.556 3
 UniProt:Q9UHC7 MKRN1  2 0.556 3
 UniProt:P55072 VCP  8 0.556 3
 UniProt:P62879 GNB2  4 0.556 3
 UniProt:Q9BVG3 TRIM62  1 0.556 3
 UniProt:Q86XT4 TRIM50  1 0.556 5
 UniProt:Q9BYV2 TRI54      0.556 3
 UniProt:Q6FHY5 Q6FHY5      0.556 3
 UniProt:Q8N6D2 RNF182  1 0.556 3
 UniProt:Q96B67 ARRD3      0.556 5
 UniProt:Q9HAC8 UBTD1      0.556 3
 IntAct:EBI-22462114 CCSB ORF ID      0.556 3
 IntAct:EBI-23192465 CCSB ORF ID      0.556 3
 UniProt:Q6PCD5 RFWD3      0.553 2
 UniProt:Q9UKV5 AMFR  1 0.553 2
 UniProt:Q9NS56 TOPORS  2 0.547 2
 UniProt:O88846  1 0.544 4
 UniProt:Q9Y4K3 TRAF6  8 0.527 2
 UniProt:Q96EP1 CHFR      0.488 2
 UniProt:Q9NZS9 BFAR      0.488 2
 UniProt:Q86Y13 DZIP3  1 0.488 2
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