Reactome | RBM14 [nucleoplasm]

RBM14 [nucleoplasm]

Stable Identifier

R-HSA-8938345

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

RNA-binding protein 14, RBM14_HUMAN, Co-activator activator, CoAA

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q96PK6 RBM14

Gene Names

RBM14, SIP

Chain

chain:1-669

Reference Genes

BioGPS Gene:100526737 RBM14

BioGPS Gene:10432 RBM14

COSMIC (genes):RBM14 RBM14

CTD Gene:100526737 RBM14

CTD Gene:10432 RBM14

dbSNP Gene:100526737 RBM14

dbSNP Gene:10432 RBM14

ENSEMBL:ENSG00000239306 RBM14

HGNC:14219 RBM14

KEGG:hsa:100526737 RBM14

KEGG:hsa:10432 RBM14

Monarch:100526737 RBM14

Monarch:10432 RBM14

NCBI Gene:100526737 RBM14

NCBI Gene:10432 RBM14

OMIM:612409 RBM14

UCSC:Q96PK6 RBM14

Reference Transcript

Other Identifiers

10432

11745257_a_at

11745258_s_at

11751756_a_at

11754108_a_at

1555639_PM_a_at

1555639_a_at

204178_PM_s_at

204178_s_at

239635_PM_at

239635_at

3336379

3336380

3336381

3336382

3336383

3336384

3336385

3336386

3336387

3336388

3336389

3336390

3336391

3336393

3336394

3336403

3336404

3336405

3336406

3336407

3336408

3336414

3336416

41460_at

58613_r_at

7941694

7941702

7941707

A_14_P116367

A_14_P117093

A_23_P150255

A_23_P161644

A_33_P3378925

A_33_P3378935

GE523397

GE54717

GO:0000398

GO:0002218

GO:0002376

GO:0003676

GO:0003723

GO:0003729

GO:0005515

GO:0005634

GO:0005654

GO:0005667

GO:0005730

GO:0005737

GO:0006325

GO:0006355

GO:0006915

GO:0007369

GO:0009725

GO:0012501

GO:0016071

GO:0016607

GO:0030374

GO:0043226

GO:0045087

GO:0045815

GO:0045944

GO:0046600

GO:0060090

GO:0098534

GO:0098542

GO:0140110

GO:1902151

GO:1990904

GO:1990935

HMNXSV003030949

HMNXSV003041752

Hs.17126.0.A1_3p_at

Hs2.11170.3.S1_3p_s_at

ILMN_1657701

ILMN_1700604

PH_hs_0026880

PH_hs_0030990

g5454063_3p_a_at

p33904

Participates

as a component of

RUNX2:RBM14 [nucleoplasm] (Homo sapiens)

as an input of

RMB14 binds RUNX2 (Homo sapiens)

Inferred To

Homologues of RBM14 [nucleoplasm] (Danio rerio)

Rbm14 [nucleoplasm] (Mus musculus)

rbm4.2 [nucleoplasm] (Danio rerio)

rnp-1 [nucleoplasm] (Caenorhabditis elegans)

RBM14 [nucleoplasm] (Bos taurus)

RBM14 [nucleoplasm] (Canis familiaris)

RBM14 [nucleoplasm] (Danio rerio)

RBM14 [nucleoplasm] (Gallus gallus)

RBM14 [nucleoplasm] (Sus scrofa)

lark [nucleoplasm] (Drosophila melanogaster)

rbm4.1 [nucleoplasm] (Danio rerio)

Cross References

RefSeq

NP_006319.1, NP_001185766.1, NP_001185774.1, NP_001185765.1

OpenTargets

ENSG00000239306

ENSEMBL

ENST00000310137, ENSP00000377548, ENSP00000386995, ENST00000393979, ENSP00000311747, ENST00000409738

HPA

ENSG00000239306-RBM14

PRO

Q96PK6

Pharos - Targets

Q96PK6

GlyGen

Q96PK6

PDB

2DNP

Interactors (39)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P61978 HNRNPK	2	HNRNPK [nucleoplasm] (R-HSA-71945) polySUMO2-K422-HNRNPK [nucleoplasm] (R-HSA-4570532)	0.666	4
UniProt:Q13363 CTBP1	3	CTBP1 [nucleoplasm] (R-HSA-212372) polySUMO2,3-K428-CTBP1 [nucleoplasm] (R-HSA-3108226) monoSUMO1-K428-CTBP1 [nucleoplasm] (R-HSA-3108200)	0.643	4
UniProt:P13569 CFTR	17	misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) CFTR [plasma membrane] (R-HSA-383188) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR G542* [plasma membrane] (R-HSA-5678986) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) ub-CFTR F508del [cytosol] (R-HSA-8866838) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR [endosome membrane] (R-HSA-6782965) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [lysosomal membrane] (R-HSA-5627279) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104)	0.64	13
UniProt:P09651 HNRNPA1	2	HNRNPA1 [nucleoplasm] (R-HSA-71927) HNRNPA1 [cytosol] (R-HSA-9727902)	0.615	3
UniProt:P61978-2 HNRNPK			0.601	4
UniProt:Q8IUH3 RBM45			0.558	4
UniProt:Q9NSC5 HOMER3	1	HOMER3 [cytosol] (R-HSA-6794236)	0.556	3
UniProt:P28799 GRN	2	GRN [azurophil granule lumen] (R-HSA-6799168) GRN [extracellular region] (R-HSA-6806217)	0.556	3
UniProt:Q86V38 Q86V38			0.556	3
UniProt:Q8NI38 IKBD			0.556	3
UniProt:O60333-2 KIF1B			0.556	3
UniProt:Q9Y3C5 RNF11			0.556	3
UniProt:P07196 NEFL	1	NEFL [cytosol] (R-HSA-432284)	0.556	3
UniProt:Q5VWX1 KHDRBS2	2	KHDRBS2 [nucleoplasm] (R-HSA-8849028) p-Y-KHDRBS2 [nucleoplasm] (R-HSA-8849031)	0.556	3
UniProt:Q8IUI8 CRLF3			0.556	3
UniProt:O76024 WFS1	3	WFS1 [endoplasmic reticulum lumen] (R-HSA-8956747) p-WFS1 [endoplasmic reticulum lumen] (R-HSA-8956998) WFS1 [endoplasmic reticulum membrane] (R-HSA-535474)	0.556	3
UniProt:Q96EX3 DYNC2I2	2	WDR34 [ciliary tip] (R-HSA-5625407) WDR34 [cilium] (R-HSA-5624900)	0.527	2
UniProt:P28335 HTR2C	1	HTR2C [plasma membrane] (R-HSA-390965)	0.527	2
UniProt:Q15527 SURF2			0.527	2
UniProt:Q9H8J5 MANS1			0.527	2
UniProt:P00740 F9	20	F9(227-461) R384L [plasma membrane] (R-HSA-9668263) 3OHD110-F9(29-461) N43L [endoplasmic reticulum lumen] (R-HSA-9673207) 3OHD110-F9(29-461) N46S [endoplasmic reticulum lumen] (R-HSA-9673232) 3OHD110-F9(29-461) N43Q [endoplasmic reticulum lumen] (R-HSA-9673217) 3OHD110-F9(29-461) N43W [endoplasmic reticulum lumen] (R-HSA-9673235) 12xCbxE-3D-F9(47-461) R191H [extracellular region] (R-HSA-9673404) F9(29-461) R43Q [extracellular region] (R-HSA-9673228) F9(29-461) R43W [extracellular region] (R-HSA-9673213) 12xCbxE-3D-F9(47-461) R191C [extracellular region] (R-HSA-9673391) F9(29-461) R46S [extracellular region] (R-HSA-9673193) 12xCbxE-3D-F9(47-461) R226W [extracellular region] (R-HSA-9673403) F9(29-461) R43L [extracellular region] (R-HSA-9673205) 12xCbxE-3D-F9(47-461) R226Q [extracellular region] (R-HSA-9673415) 12xCbxE-3D-F9(47-461) R226G [extracellular region] (R-HSA-9673418) F9(227-461) G409V [plasma membrane] (R-HSA-9671020) F9(227-461) I443T [plasma membrane] (R-HSA-9670908) F9(227-461) S411G [plasma membrane] (R-HSA-9671021) F9(227-461) G363E [plasma membrane] (R-HSA-9670894) F9(227-461) G363R [plasma membrane] (R-HSA-9670862) F9(227-461) D410H [plasma membrane] (R-HSA-9671007)	0.527	2
UniProt:P48052 CPA2	1	pro-CPA2 [zymogen granule] (R-HSA-9922737)	0.527	2
UniProt:O75843 AP1G2	1	AP1G2 [Golgi membrane] (R-HSA-5216197)	0.527	2
UniProt:Q13573 SNW1	1	SNW1 [nucleoplasm] (R-HSA-351663)	0.527	2
UniProt:Q9Y4K0 LOXL2	3	LOXL2(26-?) [extracellular region] (R-HSA-2022106) LOXL2 [extracellular region] (R-HSA-2022142) LOXL2(?-774) [extracellular region] (R-HSA-2022136)	0.527	2
UniProt:Q96CS3 FAF2	3	FAF2 [cytosol] (R-HSA-6781921) FAF2 [extracellular region] (R-HSA-6806183) FAF2 [azurophil granule lumen] (R-HSA-6799138)	0.527	2
UniProt:Q9H5K3 POMK	1	POMK [endoplasmic reticulum membrane] (R-HSA-8879120)	0.527	2
UniProt:P43243 MATR3			0.527	2
UniProt:O15027 SEC16A	1	SEC16A [cytosol] (R-HSA-5685728)	0.527	2
UniProt:O95704 APBB3			0.527	2
UniProt:Q9Y2I8 WDR37			0.527	2
UniProt:Q53GT1 KLHL22	1	KLHL22 [cytosol] (R-HSA-8863210)	0.527	2
UniProt:Q9H813 PACC1			0.527	2
UniProt:O75351 VPS4B	1	VPS4B [cytosol] (R-HSA-917719)	0.527	2
UniProt:Q96PU8 QKI	2	QKI(1-504)-p-RAF1(278- 648) fusion [cytosol] (R-HSA-6802546) QKI(1-504)-RAF1(278-648) fusion [cytosol] (R-HSA-6802466)	0.519	2
UniProt:P0DTD1-PRO_0000449619 REP			0.508	2
UniProt:P61981 YWHAG	1	YWHAG [cytosol] (R-HSA-380312)	0.483	2
UniProt:Q92731 ESR2	5	ESR2 [cytosol] (R-HSA-9020970) ESR2 [nucleoplasm] (R-HSA-446165) Me-PalmS-ESR2 [plasma membrane] (R-HSA-9637787) PalmS-ESR2 [plasma membrane] (R-HSA-9021059) PalmS-ESR2 [cytosol] (R-HSA-9020979)	0.462	2
UniProt:P03372 ESR1	10	ESR1 [cytosol] (R-HSA-9020968) ESR1 [nucleoplasm] (R-HSA-446168) Me260-PalmS-ESR1 [plasma membrane] (R-HSA-9637788) PalmS-ESR1 [plasma membrane] (R-HSA-9021057) PalmS-ESR1 [cytosol] (R-HSA-9020974) Me260-ESR1 [cytosol] (R-HSA-9632177) p-S167-ESR1 [cytosol] (R-HSA-9841254) p-S167-ESR1 [nucleoplasm] (R-HSA-9841867) monoSUMO1-5K-ESR1 [nucleoplasm] (R-HSA-4090302) p-S118-ESR1 [nucleoplasm] (R-HSA-9024210)	0.462	2

Cite Us!