Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
Ub:UBE2L3 [cytosol]
Stable Identifier
R-HSA-8938763
Type
Complex
Species
Homo sapiens
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
Protein ubiquitination (Homo sapiens)
E3 ubiquitin ligases ubiquitinate target proteins (Homo sapiens)
RNF144A binds PRKDC and Ubiquitin:UBE2L3 (Homo sapiens)
RNF144A:PRKDC:Ub:UBE2L3 [cytosol] (Homo sapiens)
Ub:UBE2L3 [cytosol] (Homo sapiens)
Ub:UBE2L3 [cytosol] (Homo sapiens)
RNF144A polyubiquitinates PRKDC (Homo sapiens)
RNF144A:PRKDC:Ub:UBE2L3 [cytosol] (Homo sapiens)
Ub:UBE2L3 [cytosol] (Homo sapiens)
Ub:UBE2L3 [cytosol] (Homo sapiens)
Programmed Cell Death (Homo sapiens)
Regulated Necrosis (Homo sapiens)
RIPK1-mediated regulated necrosis (Homo sapiens)
Regulation of necroptotic cell death (Homo sapiens)
ITCH polyubiquitinates MLKL at K50 (Homo sapiens)
p-S-RIPK1:p-S-RIPK3:p-T,S-MLKL:ITCH:Ub:UBE2L3 [cytosol] (Homo sapiens)
Ub:UBE2L3 [cytosol] (Homo sapiens)
MLKL binds ITCH (Homo sapiens)
Ub:UBE2L3 [cytosol] (Homo sapiens)
p-S-RIPK1:p-S-RIPK3:p-T,S-MLKL:ITCH:Ub:UBE2L3 [cytosol] (Homo sapiens)
Ub:UBE2L3 [cytosol] (Homo sapiens)
PRKN polyubiquitinates RIPK3 (Homo sapiens)
RIPK3:p-S9-PRKN:Ub:UBE2L3 [cytosol] (Homo sapiens)
Ub:UBE2L3 [cytosol] (Homo sapiens)
RIPK3 binds p-S9-PRKN (Homo sapiens)
RIPK3:p-S9-PRKN:Ub:UBE2L3 [cytosol] (Homo sapiens)
Ub:UBE2L3 [cytosol] (Homo sapiens)
Ub:UBE2L3 [cytosol] (Homo sapiens)
Signal Transduction (Homo sapiens)
Death Receptor Signaling (Homo sapiens)
TNF signaling (Homo sapiens)
Regulation of TNFR1 signaling (Homo sapiens)
LUBAC binds CFLAR (Homo sapiens)
CFLAR:LUBAC:Ub:UBE2D3 [cytosol] (Homo sapiens)
Ub:UBE2L3 [cytosol] (Homo sapiens)
Ub:UBE2L3 [cytosol] (Homo sapiens)
LUBAC ubiquitinates CFLAR at K351, K353 (Homo sapiens)
CFLAR:LUBAC:Ub:UBE2D3 [cytosol] (Homo sapiens)
Ub:UBE2L3 [cytosol] (Homo sapiens)
LUBAC ubiquitinates RIPK1 at K627 (Homo sapiens)
Ub:UBE2L3 [cytosol] (Homo sapiens)
SPATA2:CYLD-bound LUBAC ubiquitinates RIPK1 at K627 within the TNFR1 signaling complex (Homo sapiens)
Ub:UBE2L3 [cytosol] (Homo sapiens)
Participants
components
Ub [cytosol]
(Homo sapiens)
Ub-C86-UBE2L3 [cytosol]
(Homo sapiens)
Participates
as an input of
RNF144A polyubiquitinates PRKDC (Homo sapiens)
RNF144A binds PRKDC and Ubiquitin:UBE2L3 (Homo sapiens)
LUBAC binds CFLAR (Homo sapiens)
SPATA2:CYLD-bound LUBAC ubiquitinates RIPK1 at K627 within the TNFR1 signaling complex (Homo sapiens)
LUBAC ubiquitinates RIPK1 at K627 (Homo sapiens)
RIPK3 binds p-S9-PRKN (Homo sapiens)
MLKL binds ITCH (Homo sapiens)
as a component of
RNF144A:PRKDC:Ub:UBE2L3 [cytosol] (Homo sapiens)
CFLAR:LUBAC:Ub:UBE2D3 [cytosol] (Homo sapiens)
RIPK3:p-S9-PRKN:Ub:UBE2L3 [cytosol] (Homo sapiens)
p-S-RIPK1:p-S-RIPK3:p-T,S-MLKL:ITCH:Ub:UBE2L3 [cytosol] (Homo sapiens)
Inferred To
Ub:UBE2L3 [cytosol]
(Bos taurus)
Ub:UBE2L3 [cytosol]
(Caenorhabditis elegans)
Ub:UBE2L3 [cytosol]
(Canis familiaris)
Ub:UBE2L3 [cytosol]
(Danio rerio)
Ub:UBE2L3 [cytosol]
(Dictyostelium discoideum)
Ub:UBE2L3 [cytosol]
(Drosophila melanogaster)
Ub:UBE2L3 [cytosol]
(Gallus gallus)
Ub:UBE2L3 [cytosol]
(Mus musculus)
Ub:UBE2L3 [cytosol]
(Rattus norvegicus)
Ub:UBE2L3 [cytosol]
(Sus scrofa)
Ub:UBE2L3 [cytosol]
(Xenopus tropicalis)
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text