IL3 gene transcription is stimulated by RUNX1 and ELF1

Stable Identifier
R-HSA-8938981
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
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Binding of the RUNX1:CBFB complex associated with ELF1, an ETS family member, to the promoter of the IL3 gene, encoding interleukin-3, stimulates IL3 transcription (Mao et al. 1999).
Literature References
PubMed ID Title Journal Year
10207087 Functional and physical interactions between AML1 proteins and an ETS protein, MEF: implications for the pathogenesis of t(8;21)-positive leukemias

Miyazaki, Y, Zhang, J, Nimer, SD, Mao, S, Frank, RC

Mol. Cell. Biol. 1999
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