Reactome | GPI-LY6E [plasma membrane]

GPI-LY6E [plasma membrane]

Stable Identifier

R-HSA-8940767

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Lymphocyte antigen 6E, LY6E_HUMAN

Locations in the PathwayBrowser for interactor UniProt:Q96HH6 TMM19

Expand all

External Reference Information

External Reference

UniProt:Q16553 LY6E

Gene Names

LY6E, 9804, RIGE, SCA2, TSA1

Chain

signal peptide:1-20, chain:21-101, propeptide:102-131

Reference Genes

BioGPS Gene:4061 LY6E

COSMIC (genes):LY6E LY6E

CTD Gene:4061 LY6E

dbSNP Gene:4061 LY6E

ENSEMBL:ENSG00000160932 LY6E

HGNC:6727 LY6E

KEGG:hsa:4061 LY6E

Monarch:4061 LY6E

NCBI Gene:4061 LY6E

OMIM:601384 LY6E

UCSC:Q16553 LY6E

Reference Transcript

Other Identifiers

11715419_at

17073259

202145_PM_at

202145_at

3119346

3119347

3119348

3119349

3119350

3119351

3119352

3119353

3119354

3119355

3119356

3119357

3119358

3119359

3119361

3119362

3119363

3119365

37360_at

4061

8148572

A_14_P121295

A_24_P317762

GE59344

GO:0005515

GO:0005576

GO:0005886

GO:0007166

GO:0016020

GO:0030550

GO:0033130

GO:0045202

GO:0046597

GO:0095500

GO:0098552

GO:0098772

ILMN_1695404

PH_hs_0004480

TC08000814.hg

U66711_rna1_s_at

g4505048_3p_at

g4505048_3p_x_at

Participates

as a member of

GPI-anchored proteins [plasma membrane] (Homo sapiens)

This entity regulates

Positively

Dengue virion gets internalized (Homo sapiens)

Other forms of this molecule

cleaved GPI-LY6E [extracellular region]

Inferred To

BP1009 [plasma membrane] (Drosophila melanogaster)

Ly6e [plasma membrane] (Mus musculus)

Ly6e [plasma membrane] (Rattus norvegicus)

LY6EL [plasma membrane] (Gallus gallus)

LY6E [plasma membrane] (Bos taurus)

LY6E [plasma membrane] (Canis familiaris)

LY6E [plasma membrane] (Sus scrofa)

Modified Residues

Name

L-serine amide (GPI-anchor amidated amino acid carboxyl end residue(1−)) at 101

Coordinate

101

Modification

GPI-anchor amidated amino acid carboxyl end residue(1−)

PsiMod Name

L-serine amide

PsiMod Definition

A protein modification that effectively converts an L-serine residue to L-serine amide.

Cross References

RefSeq

NP_001120685.1, NP_002337.1

ENSEMBL

ENST00000522971, ENSP00000488556, ENST00000521003, ENST00000633451, ENST00000632424, ENSP00000488559, ENSP00000487664, ENSP00000482517, ENSP00000428169, ENSP00000427915, ENST00000631568, ENST00000521699, ENST00000429120, ENST00000632519, ENSP00000428159, ENSP00000428572, ENST00000632516, ENST00000632812, ENST00000292494, ENSP00000488443, ENSP00000488421, ENST00000619718, ENST00000522024, ENST00000520466, ENSG00000278032, ENST00000517503, ENSP00000292494, ENSP00000414307, ENSP00000428427, ENSP00000428442, ENSP00000488891, ENSG00000160932

OpenTargets

ENSG00000160932

GeneCards

LY6E

HPA

ENSG00000160932-LY6E

PRO

Q16553

Pharos - Targets

Q16553

GlyGen

Q16553

Interactors (5)

Accession	Confidence Score	Evidence (IntAct)
UniProt:P0DTD1-PRO_0000449624 REP	0.556	3
UniProt:Q9NV12 TM140	0.556	3
UniProt:A5PKU2 A5PKU2	0.556	3
UniProt:Q6ZSS7 MFSD6	0.556	3
UniProt:Q96HH6 TMM19	0.556	3