Reactome | WAC [nucleoplasm]

WAC [nucleoplasm]

Stable Identifier

R-HSA-8942150

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

WW domain-containing adapter protein with coiled-coil, WAC_HUMAN

Locations in the PathwayBrowser for interactor UniProt:Q9Y228 T3JAM

Expand all

External Reference Information

External Reference

UniProt:Q9BTA9 WAC

Gene Names

WAC, KIAA1844

Chain

chain:1-647

Reference Genes

BioGPS Gene:51322 WAC

COSMIC (genes):WAC WAC

CTD Gene:51322 WAC

dbSNP Gene:51322 WAC

ENSEMBL:ENSG00000095787 WAC

ENSEMBL:ENSG00000095787.26 WAC

HGNC:17327 WAC

KEGG Gene (Homo sapiens):51322 WAC

Monarch:51322 WAC

NCBI Gene:51322 WAC

OMIM:615049 WAC

UCSC:Q9BTA9 WAC

Reference Transcript

Other Identifiers

11739831_s_at

11742693_a_at

11742694_s_at

11742695_a_at

11742696_s_at

11752829_a_at

16703520

217742_PM_s_at

217742_s_at

219679_PM_s_at

219679_s_at

222389_PM_s_at

222389_s_at

222390_PM_at

222390_at

230154_PM_at

230154_at

3240348

3240349

3240350

3240351

3240352

3240353

3240354

3240356

3240357

3240358

3240361

3240362

3240363

3240383

3240388

3240390

3240391

3240397

3240398

3240405

3240409

3240411

3240412

3240414

3240415

3240417

3240419

3240422

3240423

3240424

3240425

3240426

3240427

3240428

3240429

3240430

3240451

43448_at

45348_at

46243_at

46244_g_at

51322

53567_at

60884_g_at

7926851

A_14_P117432

A_23_P201996

A_23_P201998

A_24_P240912

A_33_P3378689

GE82151

GO:0000278

GO:0000993

GO:0003682

GO:0005515

GO:0005634

GO:0005654

GO:0005681

GO:0006325

GO:0006338

GO:0006351

GO:0006355

GO:0006914

GO:0006974

GO:0010390

GO:0010506

GO:0016239

GO:0016607

GO:0023052

GO:0030163

GO:0031571

GO:0032435

GO:0036211

GO:0043226

GO:0045893

GO:1904263

HMNXSV003026064

Hs.44035.0.A1_3p_at

Hs.70333.0.S1_3p_a_at

Hs.70333.0.S3_3p_at

ILMN_1669727

ILMN_2323526

PH_hs_0024133

PH_hs_0032916

TC10000196.hg

TC10001962.hg

g7706169_3p_a_at

g8924074_3p_s_at

Participates

as an output of

RNF20:RNF40 monoubiquitinates Histone H2B (Homo sapiens)

as a component of

PAF1c:WAC:RNF20:RNF40:Ub:UBE2A,B:HIST1H2B [nucleoplasm] (Homo sapiens)

as an input of

RNF20:RNF40 binds PAF complex, Ubiquitin:UBE2A,B (Ubiquitin:RAD6), WAC and Histone H2B (Homo sapiens)

Inferred To

wac-1.1 [nucleoplasm] (Caenorhabditis elegans)

Ghost homologue of WAC [nucleoplasm] (Dictyostelium discoideum)

Wac [nucleoplasm] (Mus musculus)

Wac [nucleoplasm] (Rattus norvegicus)

waca [nucleoplasm] (Danio rerio)

wac [nucleoplasm] (Xenopus tropicalis)

wcy [nucleoplasm] (Drosophila melanogaster)

WAC [nucleoplasm] (Bos taurus)

WAC [nucleoplasm] (Canis familiaris)

WAC [nucleoplasm] (Gallus gallus)

WAC [nucleoplasm] (Sus scrofa)

Cross References

RefSeq

XP_011517793.1, NP_567823.1, NP_567822.1, NP_057712.2

OpenTargets

ENSG00000095787

HPA

ENSG00000095787-WAC

GeneCards

Q9BTA9

Ensembl

ENSP00000400848, ENST00000375664, ENSP00000311106, ENST00000354911, ENSP00000506624, ENSP00000415727, ENSP00000506445, ENSP00000346986, ENSP00000364816, ENST00000347934, ENST00000679428, ENST00000439676, ENST00000679398, ENST00000442148, ENSG00000095787

PRO

Q9BTA9

Pharos - Targets

Q9BTA9

Orphanet

25031

Interactors (10)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P19012 KRT15	1	KRT15 [cytosol] (R-HSA-6809589)	0.666	4
IntAct:EBI-10171556 147700			0.556	3
UniProt:Q8TDW5 SYTL5			0.556	3
UniProt:Q8WWB3 DYDC1			0.556	3
UniProt:Q6P597 KLC3	1	KLC3 [cytosol] (R-HSA-983232)	0.556	3
UniProt:Q9Y228 T3JAM			0.556	3
UniProt:Q5JR59 MTUS2			0.556	3
UniProt:Q13077 TRAF1	3	TRAF1 [cytosol] (R-HSA-5634163) TRAF1(1-163) [cytosol] (R-HSA-5634199) TRAF1(164-416) [cytosol] (R-HSA-5634204)	0.556	3
UniProt:Q16236 NFE2L2	13	p-S,T,S558-NFE2L2 [nucleoplasm] (R-HSA-9795736) p-S40, S344, S347- NFE2L2 [nucleoplasm] (R-HSA-9762050) p-S344, S347,T-NFE2L2 [nucleoplasm] (R-HSA-9762048) ub-p-S40, S335, S338- NFE2L2 [nucleoplasm] (R-HSA-9762058) ub-p-S335, S338,T-NFE2L2 [nucleoplasm] (R-HSA-9762055) ub-NFE2L2 [cytosol] (R-HSA-9758077) p-S40-18 AcK-NFE2L2 [nucleoplasm] (R-HSA-9760018) p-S,T-18 AcK-NFE2L2 [nucleoplasm] (R-HSA-9760033) NFE2L2 [cytosol] (R-HSA-201566) p-S,T-NFE2L2 [cytosol] (R-HSA-8932311) p-S40-NFE2L2 [cytosol] (R-HSA-8932290) p-S,T-NFE2L2 [nucleoplasm] (R-HSA-9715110) p-S40-NFE2L2 [nucleoplasm] (R-HSA-9715109)	0.556	3
UniProt:Q99996-2 AKAP9			0.556	3

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