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'canonical' WNT target genes:TCF/LEF [nucleoplasm]
Stable Identifier
R-HSA-8944354
Type
Complex
Species
Homo sapiens
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by WNT (Homo sapiens)
Degradation of beta-catenin by the destruction complex (Homo sapiens)
Repression of WNT target genes (Homo sapiens)
TCF/LEF binds WNT promoters (Homo sapiens)
'canonical' WNT target genes:TCF/LEF [nucleoplasm] (Homo sapiens)
TLE recruits HDAC1 to WNT promoters (Homo sapiens)
'canonical' WNT target gene:TCF/LEF:TLE tetramer [nucleoplasm] (Homo sapiens)
'canonical' WNT target genes:TCF/LEF [nucleoplasm] (Homo sapiens)
'canonical' WNT target genes:TCF/LEF:TLE tetramer:HDAC1 [nucleoplasm] (Homo sapiens)
'canonical' WNT target gene:TCF/LEF:TLE tetramer [nucleoplasm] (Homo sapiens)
'canonical' WNT target genes:TCF/LEF [nucleoplasm] (Homo sapiens)
TLE tetramers bind TCF/LEF at WNT promoters (Homo sapiens)
'canonical' WNT target gene:TCF/LEF:TLE tetramer [nucleoplasm] (Homo sapiens)
'canonical' WNT target genes:TCF/LEF [nucleoplasm] (Homo sapiens)
'canonical' WNT target genes:TCF/LEF [nucleoplasm] (Homo sapiens)
Transcription of canonical WNT targets is repressed by the TLE:HDAC and TCF/CTBP complexes (Homo sapiens)
'canonical' WNT target genes:TCF/LEF:TLE tetramer:HDAC1 [nucleoplasm] (Homo sapiens)
'canonical' WNT target gene:TCF/LEF:TLE tetramer [nucleoplasm] (Homo sapiens)
'canonical' WNT target genes:TCF/LEF [nucleoplasm] (Homo sapiens)
Participants
components
'canonical' WNT target genes [nucleoplasm]
(Homo sapiens)
TCF/LEF [nucleoplasm]
(Homo sapiens)
Participates
as an output of
TCF/LEF binds WNT promoters (Homo sapiens)
as a component of
'canonical' WNT target gene:TCF/LEF:TLE tetramer [nucleoplasm] (Homo sapiens)
as an input of
TLE tetramers bind TCF/LEF at WNT promoters (Homo sapiens)
Inferred To
'canonical' WNT target genes:TCF/LEF [nucleoplasm]
(Bos taurus)
'canonical' WNT target genes:TCF/LEF [nucleoplasm]
(Caenorhabditis elegans)
'canonical' WNT target genes:TCF/LEF [nucleoplasm]
(Canis familiaris)
'canonical' WNT target genes:TCF/LEF [nucleoplasm]
(Danio rerio)
'canonical' WNT target genes:TCF/LEF [nucleoplasm]
(Drosophila melanogaster)
'canonical' WNT target genes:TCF/LEF [nucleoplasm]
(Gallus gallus)
'canonical' WNT target genes:TCF/LEF [nucleoplasm]
(Mus musculus)
'canonical' WNT target genes:TCF/LEF [nucleoplasm]
(Rattus norvegicus)
'canonical' WNT target genes:TCF/LEF [nucleoplasm]
(Sus scrofa)
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