NLRP4:DTX4:STING:p-S172-TBK1:IRF3 [cytoplasmic vesicle membrane]

Stable Identifier
R-HSA-8948707
Type
Complex
Species
Homo sapiens
Compartment
cytoplasmic vesicle membrane
Locations in the PathwayBrowser
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Literature References
PubMed ID Title Journal Year
22388039 NLRP4 negatively regulates type I interferon signaling by targeting the kinase TBK1 for degradation via the ubiquitin ligase DTX4

Wang, HY, Cui, J, Songyang, Z, Li, Y, Wang, RF, Liu, D, Zhu, L

Nat. Immunol. 2012
Participants
components
Participates
as an input of
as an output of
This entity regulates
Negatively
Inferred To
NLRP4:DTX4:STING:p-S172-TBK1:IRF3 [cytoplasmic vesicle membrane] (Bos taurus)
NLRP4:DTX4:STING:p-S172-TBK1:IRF3 [cytoplasmic vesicle membrane] (Danio rerio)
NLRP4:DTX4:STING:p-S172-TBK1:IRF3 [cytoplasmic vesicle membrane] (Gallus gallus)
NLRP4:DTX4:STING:p-S172-TBK1:IRF3 [cytoplasmic vesicle membrane] (Mus musculus)
NLRP4:DTX4:STING:p-S172-TBK1:IRF3 [cytoplasmic vesicle membrane] (Rattus norvegicus)
NLRP4:DTX4:STING:p-S172-TBK1:IRF3 [cytoplasmic vesicle membrane] (Sus scrofa)
NLRP4:DTX4:STING:p-S172-TBK1:IRF3 [cytoplasmic vesicle membrane] (Xenopus tropicalis)
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