Reactome | TMEM11 [mitochondrial inner membrane]

TMEM11 [mitochondrial inner membrane]

Stable Identifier

R-HSA-8949578

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial inner membrane

Synonyms

Transmembrane protein 11, mitochondrial, TMM11_HUMAN

Locations in the PathwayBrowser for interactor UniProt:Q6IN84 MRM1

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External Reference Information

External Reference

UniProt:P17152 TMEM11

Gene Names

TMEM11, C17orf35, PM1

Chain

chain:1-192

Reference Genes

BioGPS Gene:8834 TMEM11

COSMIC (genes):TMEM11 TMEM11

CTD Gene:8834 TMEM11

dbSNP Gene:8834 TMEM11

ENSEMBL:ENSG00000178307 TMEM11

HGNC:16823 TMEM11

Monarch:8834 TMEM11

NCBI Gene:8834 TMEM11

OMIM:618817 TMEM11

UCSC:P17152 TMEM11

Reference Transcript

RefSeq:NM_003876.2 TMEM11

Other Identifiers

11719865_s_at

16842472

203437_PM_at

203437_at

31860_at

3749768

3749769

3749770

3749776

3749777

3749779

3749780

3749781

3749782

8013500

8834

A_23_P107036

GE59763

GO:0003674

GO:0005515

GO:0005739

GO:0005743

GO:0005886

GO:0007005

GO:0007007

GO:0043226

GO:0061024

HMNXSV003016296

ILMN_2175265

PH_hs_0001419

TC17001264.hg

TC17002554.hg

X51804_at

g4505900_3p_at

Participates

as a component of

MIB [mitochondrial inner membrane] (Homo sapiens)

as an input of

Formation of MIB complex containing the MICOS complex causes curvature of mitochondrial inner membrane (Homo sapiens)

Cross References

OpenTargets

ENSG00000178307

ENSEMBL

ENSP00000319992, ENST00000317635

HPA

ENSG00000178307-TMEM11

PRO

P17152

Pharos - Targets

P17152

Interactors (53)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q12983 BNIP3			0.919	12
UniProt:O60238 BNIP3L	1	BNIP3L [mitochondrial outer membrane] (R-HSA-6798001)	0.841	9
UniProt:Q8N6L0 KASH5			0.696	5
UniProt:Q96BA8 CREB3L1	7	CREB3L1 [Golgi membrane] (R-HSA-8874155) CREB3L1(427-519) [Golgi membrane] (R-HSA-8874139) CREB3L1(1-426) [Golgi membrane] (R-HSA-8874153) CREB3L1 [endoplasmic reticulum membrane] (R-HSA-8874157) CREB3L1(1-375) [cytosol] (R-HSA-8874215) CREB3L1(376-426) [Golgi membrane] (R-HSA-8874213) CREB3L1(1-375) [nucleoplasm] (R-HSA-8874222)	0.666	6
UniProt:Q969F0 FATE1			0.666	4
UniProt:O43557 TNFSF14	1	TNFSF14 [plasma membrane] (R-HSA-5667149)	0.666	4
UniProt:Q9NTQ9 GJB4	1	GJB4 [endoplasmic reticulum membrane] (R-HSA-190624)	0.556	3
UniProt:P11912 CD79A	2	p-Y188,Y199-CD79A [plasma membrane] (R-HSA-983539) CD79A [plasma membrane] (R-HSA-197154)	0.556	3
UniProt:Q96KR6 F210B			0.556	3
UniProt:Q16585 SGCB	3	SGCB [endoplasmic reticulum membrane] (R-HSA-9913185) SGCB [Golgi membrane] (R-HSA-9913180) SGCB [plasma membrane] (R-HSA-9630718)	0.556	3
UniProt:Q3SXY8 ARL13B	8	PolyUb-Misfolded ARL13B [lysosomal lumen] (R-HSA-9660004) PolyUb-Misfolded ARL13B [cytosol] (R-HSA-9641129) Ub-Misfolded ARL13B [cytosol] (R-HSA-9641119) Misfolded ARL13B [cytosol] (R-HSA-9640110) Misfolded ARL13B [cilium] (R-HSA-9640116) ARL13B [cilium] (R-HSA-5618181) PolyUb-Misfolded ARL13B [late endosome lumen] (R-HSA-9659986) ARL13B [plasma membrane] (R-HSA-9716787)	0.556	3
UniProt:Q15800 MSMO1	1	MSMO1 [endoplasmic reticulum membrane] (R-HSA-194648)	0.556	3
UniProt:Q6IN84 MRM1	1	MRM1 [mitochondrial matrix] (R-HSA-6793088)	0.556	3
UniProt:Q9H2K0 MTIF3	1	MTIF3 [mitochondrial matrix] (R-HSA-5368284)	0.556	3
UniProt:Q15125 EBP	1	EBP [endoplasmic reticulum membrane] (R-HSA-195697)	0.556	3
UniProt:Q8IWU4 SLC30A8	2	SLC30A8 [Golgi membrane] (R-HSA-9817561) SLC30A8 [secretory granule membrane] (R-HSA-437106)	0.556	3
UniProt:O15552 FFAR2	1	FFAR2 [plasma membrane] (R-HSA-443944)	0.556	3
UniProt:Q3KNW5 SLC10A6	1	SLC10A6 [plasma membrane] (R-HSA-433091)	0.556	3
UniProt:Q13323 BIK			0.556	3
UniProt:O15393-2 TMPRSS2			0.556	3
IntAct:EBI-22344578 CCSB ORF ID			0.556	3
UniProt:Q96Q45-2 TMEM237			0.556	3
UniProt:Q5T7V8 GORAB			0.556	3
UniProt:O75489 NDUFS3	2	NDUFS3 [mitochondrial matrix] (R-HSA-163927) NDUFS3 [cytosol] (R-HSA-9714751)	0.556	3
UniProt:Q9BVX2 T106C			0.556	3
UniProt:O00623 PEX12	2	PEX12 [cytosol] (R-HSA-9603782) PEX12 [peroxisomal membrane] (R-HSA-8953911)	0.556	3
UniProt:O95471 CLDN7	2	CLDN7 [plasma membrane] (R-HSA-420004) CLDN7 [cell junction] (R-HSA-421241)	0.556	3
UniProt:Q6UW68 TM205			0.556	3
UniProt:Q9NUH8 TM14B			0.556	3
UniProt:Q13113 PDZ1I			0.556	3
UniProt:Q6NSX1 CCD70			0.556	3
UniProt:O60930 RNASEH1	1	RNASEH1 [mitochondrial matrix] (R-HSA-9913630)	0.556	3
UniProt:Q8WUJ1 NEUFC			0.556	3
UniProt:Q7Z5B4-5 RIC3			0.556	3
UniProt:Q8N6K0 TEX29			0.556	3
UniProt:Q86VR2 RETR3			0.556	3
UniProt:Q9GZR5 ELOVL4	1	ELOVL4 [endoplasmic reticulum membrane] (R-HSA-548705)	0.556	3
UniProt:Q5JX71 F209A			0.556	3
UniProt:O95214 LERL1			0.556	3
UniProt:Q96L08 SUSD3			0.556	3
UniProt:Q96EC8 YIPF6	2	YIPF6 [Golgi membrane] (R-HSA-434346) YIPF6 [cytoplasmic vesicle membrane] (R-HSA-434199)	0.556	3
UniProt:P32243-2 OTX2			0.556	3
UniProt:Q6PEY1 TMM88			0.556	3
UniProt:P49447 CY561			0.556	3
UniProt:Q8TBP5 F174A			0.556	3
UniProt:P15941-11 MUC1			0.556	3
UniProt:Q86VZ1 P2RY8			0.527	3
UniProt:P50895 BCAM			0.527	2
UniProt:Q92633 LPAR1	1	LPAR1 [plasma membrane] (R-HSA-419354)	0.527	2
UniProt:P30825 SLC7A1	1	SLC7A1 [plasma membrane] (R-HSA-375771)	0.527	2
UniProt:P04201 MAS			0.527	2
UniProt:P34741 SDC2	20	HS(4)-SDC2 [plasma membrane] (R-HSA-2076683) HS(6)-SDC2 [plasma membrane] (R-HSA-2076661) HS(2)-SDC2 [plasma membrane] (R-HSA-2076644) HS(1)-SDC2 [plasma membrane] (R-HSA-2076643) HS(3)-SDC2 [plasma membrane] (R-HSA-2076631) HS(5)-SDC2 [plasma membrane] (R-HSA-2076665) SDC2 [endoplasmic reticulum lumen] (R-HSA-8956741) p-SDC2 [endoplasmic reticulum lumen] (R-HSA-8956945) XylS-SDC2 [Golgi lumen] (R-HSA-2064109) Gal-Xyl-SDC2 [Golgi lumen] (R-HSA-2064132) SDC2 [Golgi lumen] (R-HSA-2054101) Gal-Gal-Xyl-SDC2 [Golgi lumen] (R-HSA-2063988) GlcA-Gal-Gal-Xyl-SDC2 [Golgi lumen] (R-HSA-2063997) HS(3)-SDC2 [Golgi lumen] (R-HSA-2076443) HS(4)-SDC2 [Golgi lumen] (R-HSA-2076356) HS(2)-SDC2 [Golgi lumen] (R-HSA-2076603) HS(1)-SDC2 [Golgi lumen] (R-HSA-2076607) Heparan(4)-SDC2 [Golgi lumen] (R-HSA-2076576) Heparan(3)-SDC2 [Golgi lumen] (R-HSA-2076361) Heparan(2)-SDC2 [Golgi lumen] (R-HSA-2076397)	0.527	2
UniProt:Q9H8X2 IPPK	2	IPPK [cytosol] (R-HSA-1604598) IPPK [nucleoplasm] (R-HSA-2023949)	0.527	2

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