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CHCHD3 (MIC19) [mitochondrial inner membrane]
Stable Identifier
R-HSA-8949583
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
mitochondrial inner membrane
Synonyms
CHCHD3, MICOS complex subunit MIC19, MIC19_HUMAN
Locations in the PathwayBrowser for interactor UniProt:Q9Y2D8 ADIP
Expand all
Organelle biogenesis and maintenance (Homo sapiens)
Mitochondrial biogenesis (Homo sapiens)
Cristae formation (Homo sapiens)
Formation of MIB complex containing the MICOS complex causes curvature of mitochondrial inner membrane (Homo sapiens)
CHCHD3 (MIC19) [mitochondrial inner membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9NX63 CHCHD3
Gene Names
CHCHD3, MIC19, MINOS3
Chain
initiator methionine:, chain:2-227
Reference Genes
BioGPS Gene:54927 CHCHD3
COSMIC (genes):CHCHD3 CHCHD3
CTD Gene:54927 CHCHD3
dbSNP Gene:54927 CHCHD3
ENSEMBL:ENSG00000106554 CHCHD3
ENSEMBL_homo_sapiens_GENE:ENSG00000106554.13 CHCHD3
HGNC:21906 CHCHD3
KEGG Gene (Homo sapiens):54927 CHCHD3
Monarch:54927 CHCHD3
NCBI Gene:54927 CHCHD3
OMIM:613748 CHCHD3
UCSC:Q9NX63 CHCHD3
Reference Transcript
RefSeq:NM_017812.3 CHCHD3
RefSeq:NM_001317177.1 CHCHD3
Other Identifiers
11757083_s_at
17063047
217972_PM_at
217972_at
2402993
2402994
2402995
3073634
3073643
3073663
3073675
3073703
3073704
3073713
3073717
3073722
3073723
3234481
46233_at
54927
8143028
A_23_P251927
GE55487
GO:0001401
GO:0005515
GO:0005576
GO:0005615
GO:0005634
GO:0005737
GO:0005739
GO:0005743
GO:0007005
GO:0007007
GO:0008053
GO:0016020
GO:0019902
GO:0042407
GO:0043226
GO:0044284
GO:0060090
GO:0061024
GO:0061617
GO:0070062
GO:0140275
HMNXSV003038176
ILMN_1673026
g8923389_3p_at
Participates
as a component of
MICOS [mitochondrial inner membrane] (Homo sapiens)
as an input of
Formation of MIB complex containing the MICOS complex causes curvature of mitochondrial inner membrane (Homo sapiens)
Other forms of this molecule
CHCHD3 [mitochondrial intermembrane space]
4xHC-CHCHD3 [mitochondrial intermembrane space]
Cross References
RefSeq
NP_060282.1
,
NP_001304106.1
OpenTargets
ENSG00000106554
GeneCards
Q9NX63
HPA
ENSG00000106554-CHCHD3
Ensembl
ENST00000262570
,
ENSG00000106554
,
ENSP00000262570
PRO
Q9NX63
Pharos - Targets
Q9NX63
Interactors (53)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9Y512 SAMM50
1
SAMM50 [mitochondrial outer membrane]
(R-HSA-1252178)
0.782
7
UniProt:Q9NW38 FANCL
2
FANCL [nucleoplasm]
(R-HSA-419520)
FANCL [cytosol]
(R-HSA-420789)
0.718
6
UniProt:Q9H2G9 BLZF1
1
BLZF1 [Golgi membrane]
(R-HSA-2422372)
0.718
6
UniProt:Q16891 IMMT
1
IMMT (MIC60) [mitochondrial inner membrane]
(R-HSA-8949569)
0.643
3
UniProt:O75431 MTX2
1
MTX2 [mitochondrial outer membrane]
(R-HSA-1252142)
0.643
4
UniProt:Q9BRQ6 CHCHD6
1
CHCHD6 (MIC25) [mitochondrial inner membrane]
(R-HSA-8949568)
0.564
2
UniProt:Q9BYB0 SHANK3
1
SHANK3 [cytosol]
(R-HSA-6794277)
0.564
2
UniProt:O76024 WFS1
3
WFS1 [endoplasmic reticulum lumen]
(R-HSA-8956747)
p-WFS1 [endoplasmic reticulum lumen]
(R-HSA-8956998)
WFS1 [endoplasmic reticulum membrane]
(R-HSA-535474)
0.556
3
UniProt:P61970 NTF2
0.556
3
UniProt:Q96KN7 RPGR1
0.556
3
UniProt:P62140 PPP1CB
4
PPP1CB [cytosol]
(R-HSA-163405)
PPP1CB [nucleoplasm]
(R-HSA-62003)
PPP1CB P49R [cytosol]
(R-HSA-9660547)
PPP1CB A56P [cytosol]
(R-HSA-9660543)
0.556
3
UniProt:Q53TS8 CTSRT
0.556
3
UniProt:Q13137 CACO2
0.556
3
UniProt:Q96R06 SPAG5
0.556
3
UniProt:Q5JVL4 EFHC1
0.556
3
UniProt:Q5VU43 MYOME
0.556
3
UniProt:P0DPK4 NOTCH2NLC
1
NOTCH2NLC [extracellular region]
(R-HSA-9908932)
0.556
3
UniProt:Q9H0I2 ENKD1
0.556
3
UniProt:Q9P209 CEP72
1
CEP72 [cytosol]
(R-HSA-380321)
0.556
3
UniProt:Q9H6L4 ARMC7
0.556
3
UniProt:Q96HA8 NTAQ1
0.556
3
UniProt:A8MQ03 CRTP1
0.556
6
IntAct:EBI-22314709 CCSB ORF ID
0.556
3
UniProt:Q8NEA9 GMCL2
0.556
3
UniProt:Q49AR9 Q49AR9
0.556
3
UniProt:P14373 TRIM27
2
TRIM27 [nucleoplasm]
(R-HSA-2997690)
TRIM27 [cytosol]
(R-HSA-8851002)
0.556
3
UniProt:Q8TAP4-4 LMO3
0.556
3
UniProt:P61981 YWHAG
1
YWHAG [cytosol]
(R-HSA-380312)
0.556
3
UniProt:Q9Y2D8 ADIP
0.556
3
UniProt:Q7Z3S9 NOTCH2NLA
1
NOTCH2NLA [extracellular region]
(R-HSA-9908935)
0.556
3
UniProt:Q63ZY3 KANK2
0.556
3
UniProt:Q15047-2 SETDB1
0.556
3
UniProt:Q8NA61 CBY2
0.556
3
UniProt:Q6A162 KRT40
1
KRT40 [cytosol]
(R-HSA-6809605)
0.556
3
UniProt:Q9BRK4 LZTS2
0.556
3
UniProt:Q13077 TRAF1
3
TRAF1 [cytosol]
(R-HSA-5634163)
TRAF1(1-163) [cytosol]
(R-HSA-5634199)
TRAF1(164-416) [cytosol]
(R-HSA-5634204)
0.556
3
UniProt:P42858 HTT
1
HTT [nucleoplasm]
(R-HSA-9023590)
0.556
6
UniProt:Q92993 KAT5
1
KAT5 [nucleoplasm]
(R-HSA-3321979)
0.556
3
UniProt:Q08379 GOLGA2
3
p-S37-GOLGA2 [Golgi membrane]
(R-HSA-2172179)
GOLGA2 [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-HSA-2167933)
GOLGA2 [Golgi membrane]
(R-HSA-6808764)
0.556
3
UniProt:Q96QF0 RAB3IP
1
RAB3IP [cytosol]
(R-HSA-5617610)
0.556
3
IntAct:EBI-10171584 80125
0.556
3
UniProt:P25800 LMO1
1
LMO1 [nucleoplasm]
(R-HSA-8956514)
0.556
3
UniProt:P62136 PPP1CA
1
PPP1CA [cytosol]
(R-HSA-163525)
0.544
2
UniProt:Q6UXV4 APOOL
3
APOOL (MIC27) [mitochondrial inner membrane]
(R-HSA-8949612)
APOOL [extracellular region]
(R-HSA-8862979)
APOOL [platelet alpha granule lumen]
(R-HSA-8863003)
0.527
4
UniProt:O96008 TOMM40
3
TOMM40 [mitochondrial intermembrane space]
(R-HSA-1267971)
TOMM40 [cytosol]
(R-HSA-1267992)
TOMM40 [mitochondrial outer membrane]
(R-HSA-1252082)
0.527
2
UniProt:Q9NVH1 DNAJC11
1
DNAJC11 [mitochondrial outer membrane]
(R-HSA-8949572)
0.527
2
UniProt:Q15834 CC85B
0.508
2
UniProt:P61006 RAB8A
6
GGC-RAB8A [cytoplasmic vesicle membrane]
(R-HSA-1445093)
RAB8A [recycling endosome membrane]
(R-HSA-8854145)
GGC-RAB8A [trans-Golgi network membrane]
(R-HSA-8876082)
GGC-RAB8A [cytosol]
(R-HSA-8874063)
RAB8A [Golgi membrane]
(R-HSA-2562535)
RAB8A [cytosol]
(R-HSA-5623399)
0.508
2
UniProt:P0DTD1-PRO_0000449629 REP
0.488
2
UniProt:Q8N6Y0 USBP1
0.488
2
UniProt:P14079 TAX
0.488
2
UniProt:Q15388 TOMM20
6
PolyUb-TOMM20 [mitochondrial outer membrane]
(R-HSA-6783144)
TOMM20 [mitochondrial outer membrane]
(R-HSA-1252091)
Ub-TOMM20 [mitochondrial outer membrane]
(R-HSA-9834976)
K48polyUb-TOMM20 [mitochondrial outer membrane]
(R-HSA-9843324)
K63polyUb-TOMM20 [mitochondrial outer membrane]
(R-HSA-9843313)
p-S65-Ub:TOMM20 [mitochondrial outer membrane]
(R-HSA-9834948)
0.483
2
UniProt:P13569 CFTR
17
PolyUb-CFTR [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869104)
PolyUb-CFTR [plasma membrane]
(R-HSA-8867595)
CFTR [lysosomal membrane]
(R-HSA-5627279)
CFTR [Golgi-associated vesicle membrane]
(R-HSA-5627079)
CFTR [endosome membrane]
(R-HSA-6782965)
PolyUb-CFTR [endosome membrane]
(R-HSA-6782976)
CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866834)
ub-CFTR F508del [cytosol]
(R-HSA-8866838)
ub-CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866842)
CFTR G542* [plasma membrane]
(R-HSA-5678986)
CFTR G551D [plasma membrane]
(R-HSA-5678977)
CFTR W1282* [plasma membrane]
(R-HSA-5678976)
CFTR F508del [plasma membrane]
(R-HSA-5678978)
CFTR N1303K [plasma membrane]
(R-HSA-5678983)
CFTR [plasma membrane]
(R-HSA-383188)
CFTR [endoplasmic reticulum membrane]
(R-HSA-8866837)
misfolded CFTR [endoplasmic reticulum membrane]
(R-HSA-8868730)
0.483
6
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