IL12B [endoplasmic reticulum lumen]

Stable Identifier
R-HSA-8950126
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
General
Interleukin-12 subunit beta have to be in the reticuum where it suffers processing by the PDI enzyme if it is going to homodimerize or heterodimerize with other subunits as Interleukin-23 alpha subunit (PMID:15720785)
Literature References
PubMed ID Title Journal Year
15720785 The metallopeptide antibiotic bacitracin inhibits interleukin-12 alphabeta and beta2 secretion

Vandenbroeck, K, Alloza, I

J. Pharm. Pharmacol. 2005
External Reference Information
External Reference
Gene Names
IL12B, NKSF2
Chain
signal peptide:1-22, chain:23-328
Reference Transcript
Other Identifiers
11737833_at
11737834_at
17002328
207901_PM_at
207901_at
2884302
2884303
2884305
2884306
2884307
2884308
2884310
2884311
2884312
2884313
2884316
3593
563_at
8115570
A_23_P7560
GE58044
GO:0001817
GO:0001916
GO:0002230
GO:0002323
GO:0002376
GO:0002827
GO:0002860
GO:0002862
GO:0004896
GO:0005125
GO:0005126
GO:0005143
GO:0005515
GO:0005576
GO:0005615
GO:0005737
GO:0005768
GO:0005783
GO:0005788
GO:0005829
GO:0005886
GO:0006954
GO:0007155
GO:0007166
GO:0008083
GO:0008283
GO:0009897
GO:0009986
GO:0010033
GO:0010224
GO:0010536
GO:0012501
GO:0016020
GO:0016477
GO:0019221
GO:0019953
GO:0019955
GO:0023052
GO:0030101
GO:0030154
GO:0031410
GO:0031906
GO:0032693
GO:0032700
GO:0032725
GO:0032729
GO:0032733
GO:0032735
GO:0032740
GO:0032760
GO:0032816
GO:0032819
GO:0032946
GO:0034105
GO:0034393
GO:0035722
GO:0036211
GO:0042088
GO:0042093
GO:0042098
GO:0042102
GO:0042104
GO:0042164
GO:0042509
GO:0042531
GO:0042802
GO:0042832
GO:0043226
GO:0043235
GO:0043382
GO:0043514
GO:0044877
GO:0045519
GO:0045672
GO:0045785
GO:0046982
GO:0048018
GO:0048662
GO:0048856
GO:0048870
GO:0050671
GO:0050709
GO:0050729
GO:0050829
GO:0051135
GO:0051142
GO:0051607
GO:0060089
GO:0070743
GO:0071222
GO:0071346
GO:0098542
GO:0098772
GO:1900747
GO:1901224
GO:1903588
GO:2000318
GO:2000330
HMNXSV003009674
ILMN_1681132
M65290_at
PH_hs_0000077
TC05001997.hg
g4504640_3p_at
Participates
Other forms of this molecule
Inferred To
Cross References
RefSeq
OpenTargets
GeneCards
PRO
Pharos - Targets
Orphanet
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