IL23A [endoplasmic reticulum lumen]

Stable Identifier
R-HSA-8950224
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
endoplasmic reticulum lumen
Synonyms
Interleukin-23 subunit alpha
Locations in the PathwayBrowser
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General
Interleukin-12 and Interleukin-23 heterodimeric proteins can be founded in Endoplasmic reticulum when its secretion is inhibited by celecoxib and its COX-2-independent analogue 4-trifluoromethyl-celecoxib (TFM-C) (PMID:20054003)
Literature References
PubMed ID Title Journal Year
20054003 Inhibition of secretion of interleukin (IL)-12/IL-23 family cytokines by 4-trifluoromethyl-celecoxib is coupled to degradation via the endoplasmic reticulum stress protein HERP

Scott, CJ, Hirabayashi, Y, Quoc, HP, McLaughlin, M, Alloza, I, Vandenbroeck, K

J. Biol. Chem. 2010
External Reference Information
External Reference
UniProt:Q9NPF7 IL23A
Gene Names
IL23A, SGRF, UNQ2498/PRO5798
Chain
signal peptide:1-19, chain:20-189
Reference Genes
BioGPS Gene:51561 IL23A
COSMIC (genes):IL23A IL23A
CTD Gene:51561 IL23A
dbSNP Gene:51561 IL23A
ENSEMBL:ENSG00000110944 IL23A
ENSEMBL_homo_sapiens_GENE:ENSG00000110944.9 IL23A
HGNC:15488 IL23A
KEGG Gene (Homo sapiens):51561 IL23A
Monarch:51561 IL23A
NCBI Gene:51561 IL23A
OMIM:605580 IL23A
UCSC:Q9NPF7 IL23A
Reference Transcript
Other Identifiers
11732301_at
16752645
220054_PM_at
220054_at
3417561
3417563
3417564
3417565
3417566
3417567
3417568
49076_at
51561
7956251
A_23_P76078
GE53760
GO:0001916
GO:0002230
GO:0002376
GO:0002827
GO:0005125
GO:0005515
GO:0005576
GO:0005615
GO:0005783
GO:0005788
GO:0006351
GO:0006355
GO:0006954
GO:0006955
GO:0007155
GO:0007165
GO:0010536
GO:0023052
GO:0030154
GO:0032693
GO:0032725
GO:0032729
GO:0032733
GO:0032735
GO:0032740
GO:0032760
GO:0032816
GO:0032819
GO:0034105
GO:0036211
GO:0042098
GO:0042102
GO:0042104
GO:0042509
GO:0042531
GO:0043226
GO:0043382
GO:0045087
GO:0045519
GO:0045672
GO:0045944
GO:0048018
GO:0048771
GO:0048856
GO:0048870
GO:0050729
GO:0050829
GO:0051135
GO:0051142
GO:0051607
GO:0070743
GO:0090023
GO:0098542
GO:0098772
GO:1901224
GO:2000318
GO:2000330
HMNXSV003045248
ILMN_1715603
PH_hs_0005407
TC12000512.hg
TC12002390.hg
g7706701_3p_at
Participates
as an input of
as a component of
Other forms of this molecule
IL23A [extracellular region]
Inferred To
Il23a [endoplasmic reticulum lumen] (Mus musculus)
Il23a [endoplasmic reticulum lumen] (Rattus norvegicus)
IL23A [endoplasmic reticulum lumen] (Bos taurus)
IL23A [endoplasmic reticulum lumen] (Canis familiaris)
IL23A [endoplasmic reticulum lumen] (Sus scrofa)
Cross References
RefSeq
OpenTargets
HPA
GeneCards
Ensembl
PRO
Pharos - Targets
PDB
Interactors (4)
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