Reactome | DCAF4 [nucleoplasm]

DCAF4 [nucleoplasm]

Stable Identifier

R-HSA-8955191

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

DDB1- and CUL4-associated factor 4, DCAF4_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q8WV16 DCAF4

Gene Names

DCAF4, WDR21, WDR21A

Chain

chain:1-495

Reference Genes

BioGPS Gene:26094 DCAF4

COSMIC (genes):DCAF4 DCAF4

CTD Gene:26094 DCAF4

dbSNP Gene:26094 DCAF4

ENSEMBL:ENSG00000119599 DCAF4

ENSEMBL_homo_sapiens_GENE:ENSG00000119599.17 DCAF4

HGNC:20229 DCAF4

KEGG Gene (Homo sapiens):26094 DCAF4

Monarch:26094 DCAF4

NCBI Gene:26094 DCAF4

OMIM:616372 DCAF4

UCSC:Q8WV16 DCAF4

Reference Transcript

Other Identifiers

11736042_a_at

11736043_a_at

16786104

226938_PM_at

226938_at

26094

3543356

3543357

3543360

3543361

3543362

3543363

3543365

3543368

3543369

3543376

3543379

3543380

3543382

3543383

3543385

3543386

62494_at

7975506

A_14_P118205

A_23_P370035

A_24_P241318

A_33_P3419234

GE87701

GE87702

GO:0005515

GO:0005634

GO:0005654

GO:0016567

GO:0036211

GO:0043226

GO:0080008

HMNXSV003021302

HMNXSV003027088

HMNXSV003045970

Hs.6107.0.S1_3p_at

ILMN_2385278

PH_hs_0023836

TC14000436.hg

Participates

as a member of

DCAF protein [nucleoplasm] (Homo sapiens)

Inferred To

WDR21A [nucleoplasm] (Bos taurus)

wdr21 [nucleoplasm] (Schizosaccharomyces pombe)

DCAF4 [nucleoplasm] (Caenorhabditis elegans)

DCAF4 [nucleoplasm] (Canis familiaris)

DCAF4 [nucleoplasm] (Dictyostelium discoideum)

DCAF4 [nucleoplasm] (Gallus gallus)

DCAF4 [nucleoplasm] (Sus scrofa)

Dcaf4 [nucleoplasm] (Mus musculus)

Dcaf4 [nucleoplasm] (Rattus norvegicus)

Cross References

RefSeq

NP_056419.2, NP_001156980.1, NP_851937.1, XP_016876697.1, XP_016876696.1, NP_851938.2, NP_001156981.1

OpenTargets

ENSG00000119599

HPA

ENSG00000119599-DCAF4

GeneCards

Q8WV16

Ensembl

ENST00000358377, ENSP00000377781, ENST00000509153, ENSP00000351147, ENST00000394234, ENST00000555042, ENSG00000119599, ENSP00000452131, ENSP00000426178

PRO

Q8WV16

Pharos - Targets

Q8WV16

PDB

3I8C

Interactors (5)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P36776 LONP1	1	LONP1 [mitochondrial matrix] (R-HSA-9838000)	0.527	3
UniProt:O60832 DKC1	1	DKC1 [nucleoplasm] (R-HSA-163102)	0.527	4
UniProt:P10809 HSPD1	6	HSPD1 [mitochondrial matrix] (R-HSA-1299448) HSPD1(1-573) [cytosol] (R-HSA-1267989) HSPD1(1-573) [mitochondrial intermembrane space] (R-HSA-1267963) HSPD1 [mitochondrial inner membrane] (R-HSA-1299455) HSPD1(1-573) [mitochondrial inner membrane] (R-HSA-1299442) HSPD1(1-26) [mitochondrial matrix] (R-HSA-8986171)	0.527	4
UniProt:Q9Y4Z2 NEUROG3	1	NEUROG3 [nucleoplasm] (R-HSA-189530)	0.527	3
UniProt:P61218 POLR2F	2	POLR2F [nucleoplasm] (R-HSA-83714) POLR2F [cytosol] (R-HSA-1964441)	0.527	3