Reactome | p-SERPINA10 [endoplasmic reticulum lumen]

p-SERPINA10 [endoplasmic reticulum lumen]

Stable Identifier

R-HSA-8956990

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endoplasmic reticulum lumen

Synonyms

SERPINA10, Protein Z-dependent protease inhibitor, ZPI_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9UK55 SERPINA10

Gene Names

SERPINA10, ZPI, UNQ707/PRO1358

Chain

signal peptide:1-21, chain:22-444

Reference Genes

BioGPS Gene:51156 SERPINA10

COSMIC (genes):SERPINA10 SERPINA10

CTD Gene:51156 SERPINA10

dbSNP Gene:51156 SERPINA10

ENSEMBL:ENSG00000140093 SERPINA10

ENSEMBL_homo_sapiens_GENE:ENSG00000140093.10 SERPINA10

ENSEMBL_homo_sapiens_GENE:ENSG00000278767.4 SERPINA10

HGNC:15996 SERPINA10

KEGG Gene (Homo sapiens):51156 SERPINA10

Monarch:51156 SERPINA10

NCBI Gene:51156 SERPINA10

OMIM:605271 SERPINA10

UCSC:Q9UK55 SERPINA10

Reference Transcript

Other Identifiers

11735745_a_at

11735746_x_at

16796237

220626_PM_at

220626_at

3577574

3577576

3577578

3577579

3577580

3577581

3577582

3577585

3577586

3577587

3577588

3577589

3577590

3577591

3577592

51156

76085_at

7981051

A_23_P128759

A_32_P116233

GE58697

GO:0004867

GO:0005515

GO:0005576

GO:0005615

GO:0005783

GO:0005788

GO:0007596

GO:0007599

GO:0008201

GO:0030414

GO:0042060

GO:0043226

GO:0048856

GO:0070062

GO:0097421

GO:0098772

HMNXSV003011410

ILMN_1793628

TC14001464.hg

g7705878_3p_at

Participates

as a member of

FAM20C products [endoplasmic reticulum lumen] (Homo sapiens)

Other forms of this molecule

SERPINA10 [endoplasmic reticulum lumen]

Inferred To

phospho-serpina10 [endoplasmic reticulum lumen] (Xenopus tropicalis)

phospho-Spn77Ba [endoplasmic reticulum lumen] (Drosophila melanogaster)

phospho-Spn28Dc [endoplasmic reticulum lumen] (Drosophila melanogaster)

phospho-p-SERPINA10 [endoplasmic reticulum lumen] (Gallus gallus)

phospho-Spn77Bc [endoplasmic reticulum lumen] (Drosophila melanogaster)

Homologues of p-SERPINA10 [endoplasmic reticulum lumen] (Drosophila melanogaster)

phospho-Spn77Bb [endoplasmic reticulum lumen] (Drosophila melanogaster)

phospho-Serpina10 [endoplasmic reticulum lumen] (Mus musculus)

phospho-Serpina10 [endoplasmic reticulum lumen] (Rattus norvegicus)

phospho-SERPINA10 [endoplasmic reticulum lumen] (Bos taurus)

Modified Residues

Name

phosphorylated residue at unknown position

PsiMod Name

phosphorylated residue [MOD:00696]

PsiMod Definition

A protein modification that effectively replaces a hydrogen atom with a phosphate group.

Cross References

RefSeq

NP_001094077.1, NP_057270.1, XP_005267790.1

OpenTargets

ENSG00000140093

HPA

ENSG00000140093-SERPINA10

GeneCards

Q9UK55

Ensembl

ENST00000614630, ENSG00000140093, ENST00000393096, ENST00000261994, ENSP00000484632, ENST00000554173, ENSP00000261994, ENSP00000450971, ENSP00000376809, ENSG00000278767

PRO

Q9UK55

Pharos - Targets

Q9UK55

Orphanet

23946

HMDB Protein

HMDBP08103

PDB

4AFX, 4AJU, 3F1S, 3H5C

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P22891 PROZ	5	PROZ(24-40) [Golgi lumen] (R-HSA-163834) PROZ(24-400) [endoplasmic reticulum lumen] (R-HSA-163816) 13xCbxE-PROZ(24-400) [endoplasmic reticulum lumen] (R-HSA-163838) 13xCbxE-PROZ(24-400) [Golgi lumen] (R-HSA-163827) 13xCbxE-PROZ [Golgi lumen] (R-HSA-163813)	0.655	7
UniProt:P00742 F10	13	11xCbxE-3D-F10(41-179) [Golgi lumen] (R-HSA-159718) factor X light chain propeptide [Golgi lumen] (R-HSA-159824) 11xCbxE-3D-F10(32-179) [Golgi lumen] (R-HSA-159774) factor X heavy chain [Golgi lumen] (R-HSA-159846) 11xCbxE-3D-F10(32-179) [endoplasmic reticulum lumen] (R-HSA-159786) factor X heavy chain [endoplasmic reticulum lumen] (R-HSA-159776) 3D-F10(32-179) [endoplasmic reticulum lumen] (R-HSA-159810) factor X activation peptide [extracellular region] (R-HSA-140785) factor X heavy chain [extracellular region] (R-HSA-140738) 11xCbxE-3D-F10(41-179) [extracellular region] (R-HSA-140687) factor Xa heavy chain [extracellular region] (R-HSA-140688) 11xCbxE-3D-F10(41-179) [plasma membrane] (R-HSA-140631) factor Xa heavy chain [plasma membrane] (R-HSA-140642)	0.558	2

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