Reactome | p-FSTL1 [endoplasmic reticulum lumen]

p-FSTL1 [endoplasmic reticulum lumen]

Stable Identifier

R-HSA-8957089

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endoplasmic reticulum lumen

Synonyms

FSTL1, Follistatin-related protein 1, FSTL1_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q12841 FSTL1

Gene Names

FSTL1, FRP

Chain

signal peptide:1-20, chain:21-308

Reference Genes

BioGPS Gene:11167 FSTL1

COSMIC (genes):FSTL1 FSTL1

CTD Gene:11167 FSTL1

dbSNP Gene:11167 FSTL1

ENSEMBL:ENSG00000163430 FSTL1

HGNC:3972 FSTL1

KEGG:hsa:11167 FSTL1

Monarch:11167 FSTL1

NCBI Gene:11167 FSTL1

OMIM:605547 FSTL1

UCSC:Q12841 FSTL1

Reference Transcript

RefSeq:NM_007085.4 FSTL1

Other Identifiers

11167

11715651_s_at

11752842_a_at

16957884

208782_PM_at

208782_at

230744_PM_at

230744_at

240891_PM_at

240891_at

2691208

2691210

2691212

2691214

2691216

2691218

2691220

2691222

2691230

2691232

2691238

2691244

2691246

2691248

2691250

2691252

2691254

2691256

2691258

2691262

2691264

2691266

2691268

2691278

2691280

2691286

2691302

2691306

2691308

2691310

2691312

45201_at

65211_at

78864_g_at

8089835

A_23_P212696

GE57441

GE836545

GE83702

GO:0005509

GO:0005515

GO:0005576

GO:0005615

GO:0005788

GO:0008201

GO:0030154

GO:0030510

GO:0043066

GO:0043226

GO:0043542

GO:0045446

GO:0048870

GO:0061484

GO:0070062

HMNXSV003014785

Hs.135513.0.A1_3p_at

Hs.42419.0.A1_3p_at

ILMN_2201678

PH_hs_0020138

TC03001691.hg

U06863_at

g12652618_3p_at

Participates

as a member of

FAM20C products [endoplasmic reticulum lumen] (Homo sapiens)

Other forms of this molecule

FSTL1 [extracellular region]

FSTL1 [endoplasmic reticulum lumen]

Inferred To

phospho-Fstl1 [endoplasmic reticulum lumen] (Mus musculus)

phospho-Fstl1 [endoplasmic reticulum lumen] (Rattus norvegicus)

phospho-p-FSTL1 [endoplasmic reticulum lumen] (Gallus gallus)

phospho-FSTL1 [endoplasmic reticulum lumen] (Bos taurus)

phospho-FSTL1 [endoplasmic reticulum lumen] (Canis familiaris)

phospho-FSTL1 [endoplasmic reticulum lumen] (Sus scrofa)

phospho-fstl1 [endoplasmic reticulum lumen] (Xenopus tropicalis)

Modified Residues

Name

phosphorylated residue at unknown position

PsiMod Name

phosphorylated residue [MOD:00696]

PsiMod Definition

A protein modification that effectively replaces a hydrogen atom with a phosphate group.

Cross References

RefSeq

NP_009016.1

ENSEMBL

ENSP00000394355, ENST00000710954, ENST00000295633, ENST00000424703, ENST00000469005, ENSP00000518554, ENSP00000418505, ENSP00000295633

OpenTargets

ENSG00000163430

HPA

ENSG00000163430-FSTL1

PRO

Q12841

Pharos - Targets

Q12841

GlyGen

Q12841

Interactors (4)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P08571 CD14	4	GPIN-CD14(20-345) [secretory granule membrane] (R-HSA-6803315) GPIN-CD14(20-345) [endosome membrane] (R-HSA-2201284) CD14(20-345) [extracellular region] (R-HSA-166025) GPIN-CD14(20-345) [plasma membrane] (R-HSA-166033)	0.658	3
UniProt:P01137 TGFB1	7	TGFB1 [extracellular region] (R-HSA-170838) TGFB1(30-278) [extracellular region] (R-HSA-2395367) TGFB1(30-278) [Golgi lumen] (R-HSA-9736812) TGFB1 [Golgi lumen] (R-HSA-177108) TGFB1(30-390) [Golgi lumen] (R-HSA-114705) TGFB1 [plasma membrane] (R-HSA-5146781) TGFB1(30-278) [platelet alpha granule lumen] (R-HSA-65936)	0.544	2
UniProt:P29459 IL12A	4	IL12A [Golgi lumen] (R-HSA-8950463) IL12A [endoplasmic reticulum lumen] (R-HSA-8950139) IL12A [late endosome lumen] (R-HSA-8950449) IL12A [extracellular region] (R-HSA-447212)	0.527	2
UniProt:P46108 CRK	1	CRK [cytosol] (R-HSA-2980677)	0.488	2