Reactome | GRB2 [cytosol]

GRB2 [cytosol]

Stable Identifier

R-HSA-8983328

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

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External Reference Information

External Reference

UniProt:P62993 GRB2

Gene Names

GRB2, ASH

Chain

chain:1-217

Reference Genes

ENSEMBL:ENSG00000177885 GRB2

Participates

as a component of

as an input of

Inferred To

Grb2 [cytosol] (Rattus norvegicus)

grb2 [cytosol] (Xenopus tropicalis)

GRB2 [cytosol] (Bos taurus)

GRB2 [cytosol] (Canis familiaris)

GRB2 [cytosol] (Gallus gallus)

GRB2 [cytosol] (Sus scrofa)

drk [cytosol] (Drosophila melanogaster)

Grb2-1 [cytosol] (Mus musculus)

Interactors (262)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P00533 EGFR	20	p-6Y-EGFR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869138) p-5Y-EGFRvIII [plasma membrane] (R-HSA-1248649) EGFRvIII [plasma membrane] (R-HSA-1214162) p-6Y-EGFR E746_A750del;T790M [plasma membrane] (R-HSA-1182985) p-6Y-EGFR L858R;T790M [plasma membrane] (R-HSA-1182984) p-6Y-EGFR A767_V769dup [plasma membrane] (R-HSA-1996343) p-6Y-EGFR N771_H773dup [plasma membrane] (R-HSA-1996342) p-6Y-EGFR K739_I744dup [plasma membrane] (R-HSA-1996346) p-6Y-EGFR D770_N771insNPG [plasma membrane] (R-HSA-1996335) p-6Y-EGFR E746_A750del [plasma membrane] (R-HSA-1181214) p-6Y-EGFR L858R [plasma membrane] (R-HSA-1173211) p-6Y-EGFR G719S [plasma membrane] (R-HSA-1169417) p-6Y-EGFR L747_P753delinsS [plasma membrane] (R-HSA-1228038) p-6Y-EGFR L747_A750delinsP [plasma membrane] (R-HSA-1228044) p-6Y-EGFR L747_T751del [plasma membrane] (R-HSA-1228041) p-6Y-EGFR L747_S752del [plasma membrane] (R-HSA-1228040) p-6Y-EGFR L747_T751delinsP [plasma membrane] (R-HSA-1228042) p-6Y-EGFR E746_T751delinsA [plasma membrane] (R-HSA-1228037) p-6Y-EGFR E746_S752delinsV [plasma membrane] (R-HSA-1228039) p-6Y-EGFR L861Q [plasma membrane] (R-HSA-1177541)	0.983	59
UniProt:P29353 SHC1	5	p-Y-SHC1 [cytosol] (R-HSA-162568) SHC1 [cytosol] (R-HSA-74680) p-Y349,Y350,Y427-SHC1 [cytosol] (R-HSA-912321) p-Y349,Y350-SHC1 [cytosol] (R-HSA-180276) p-Y427-SHC1 [cytosol] (R-HSA-74684)	0.976	33
UniProt:Q07889 SOS1	3	SOS1 [cytosol] (R-HSA-64847) SOS1 [plasma membrane] (R-HSA-983559) p-4S-SOS1 [cytosol] (R-HSA-109821)	0.972	29
UniProt:Q13191 CBLB	1	CBLB [cytosol] (R-HSA-976009)	0.967	30
UniProt:P22681 CBL	20	PolyUb,p-Y-CBL [cytosol] (R-HSA-9763893) CBL R420G [cytosol] (R-HSA-9706203) CBL R420Q [cytosol] (R-HSA-9706186) CBL Y371H [cytosol] (R-HSA-9706680) CBL H398Y [cytosol] (R-HSA-9706639) CBL P417A [cytosol] (R-HSA-9706636) CBL S376F [cytosol] (R-HSA-9706643) CBL E366_Q409del [cytosol] (R-HSA-9706179) CBL del366-477 [cytosol] (R-HSA-9706176) CBL R499L [cytosol] (R-HSA-9706678) CBL L380P [cytosol] (R-HSA-9706630) CBL L287R [cytosol] (R-HSA-9706693) CBL L380R [cytosol] (R-HSA-9706635) CBL G375P [cytosol] (R-HSA-9706219) CBL P417L [cytosol] (R-HSA-9706634) CBL H398Q [cytosol] (R-HSA-9706633) CBL P417R [cytosol] (R-HSA-9706632) CBL [cytosol] (R-HSA-112199) p-Y371-CBL [cytosol] (R-HSA-182940) p-Y700,Y731,Y774-CBL [cytosol] (R-HSA-912656)	0.963	19
UniProt:Q9UQC2 GAB2	5	p-Y643-GAB2 [cytosol] (R-HSA-9677149) p-5Y-GAB2 [cytosol] (R-HSA-8855574) GAB2 [cytosol] (R-HSA-508239) p-Y452,Y476,Y584-GAB2 [cytosol] (R-HSA-2685615) p-Y-GAB2 [cytosol] (R-HSA-912529)	0.953	16
UniProt:Q07890 SOS2	1	SOS2 [cytosol] (R-HSA-167221)	0.939	13
UniProt:O00401 WASL	4	p-Y256-WASL [cytosol] (R-HSA-2197672) N-WASP [cytosol] (R-HSA-201873) WASL [plasma membrane] (R-HSA-203010) WASL [endocytic vesicle membrane] (R-HSA-535012)	0.935	12
UniProt:P18433 PTPRA	1	PTPRA [plasma membrane] (R-HSA-388755)	0.934	16
UniProt:Q9UJM3 ERRFI			0.934	18
UniProt:Q9H706 GARE1			0.933	13
UniProt:P11274 BCR	4	BCR [cytosol] (R-HSA-195200) BCR(1-584)-FGFR1(429-822) fusion [cytosol] (R-HSA-1604524) p-Y177-BCR(1-584)-p-FGFR1(429-822) fusion [cytosol] (R-HSA-1839041) BCR(1-584)-p-FGFR1(429-822) fusion [cytosol] (R-HSA-1838979)	0.928	13
UniProt:Q13480 GAB1	4	p-Y-GAB1 [cytosol] (R-HSA-8855306) p-Y627,Y659-GAB1 [cytosol] (R-HSA-180496) p-5Y-GAB1 [cytosol] (R-HSA-180344) GAB1 [cytosol] (R-HSA-179795)	0.927	13
UniProt:P50570 DNM2	5	DNM2 [Golgi membrane] (R-HSA-2980842) DNM2 [endocytic vesicle membrane] (R-HSA-2029000) DNM2 [cytosol] (R-HSA-2213180) DNM2 [lysosomal membrane] (R-HSA-2980840) DNM2 [plasma membrane] (R-HSA-2984201)	0.926	10
UniProt:O95630 STAMBP	1	STAMBP [cytosol] (R-HSA-5693063)	0.926	10
UniProt:Q13094 LCP2	2	p-Y113,128,145-LCP2 [cytosol] (R-HSA-202175) LCP2 [cytosol] (R-HSA-202306)	0.918	18
UniProt:P04626 ERBB2	20	ERBB2 G309E [plasma membrane] (R-HSA-9665342) ERBB2 G309A [plasma membrane] (R-HSA-9665349) ERBB2 S310F [plasma membrane] (R-HSA-9665350) ERBB2 S310Y [plasma membrane] (R-HSA-9665344) p-6Y-ERBB2 G309A [plasma membrane] (R-HSA-9665381) p-6Y-ERBB2 G309E [plasma membrane] (R-HSA-9665382) p-6Y-ERBB2 S310F [plasma membrane] (R-HSA-9665379) p-6Y-ERBB2 S310Y [plasma membrane] (R-HSA-9665385) p-Y-ERBB2 L755P [plasma membrane] (R-HSA-9654268) p-Y-ERBB2 I767M [plasma membrane] (R-HSA-9654303) p-Y-ERBB2 T798I [plasma membrane] (R-HSA-9654618) p-Y-ERBB2 Y772_A775dup [plasma membrane] (R-HSA-9665652) p-Y-ERBB2 T862A [plasma membrane] (R-HSA-9654695) p-Y-ERBB2 T798M [plasma membrane] (R-HSA-9654615) p-Y-ERBB2 H878Y [plasma membrane] (R-HSA-9654833) p-Y-ERBB2 V777L [plasma membrane] (R-HSA-9654401) p-Y-ERBB2 L755S [plasma membrane] (R-HSA-9654194) p-Y-ERBB2 V777E [plasma membrane] (R-HSA-9654397) p-Y-ERBB2 V777M [plasma membrane] (R-HSA-9654398) p-Y-ERBB2 L755M [plasma membrane] (R-HSA-9654191)	0.916	8
UniProt:Q9ULH1 ASAP1	1	ASAP1 [cytosol] (R-HSA-5620905)	0.906	12
UniProt:Q06124 PTPN11	4	p-Y542,Y580-PTPN11 [cytosol] (R-HSA-162573) PTPN11 [cytosol] (R-HSA-162563) PTPN11 [nucleoplasm] (R-HSA-8937745) p-Y542-PTPN11 [cytosol] (R-HSA-1369081)	0.905	11
UniProt:Q9Y4K4 M4K5			0.897	7
UniProt:Q05193 DNM1	3	DNM1 [plasma membrane] (R-HSA-177488) DNM1 [lysosomal membrane] (R-HSA-196150) DNM1 [cytosol] (R-HSA-2213182)	0.87	8
UniProt:Q07666 KHDRBS1	3	p-Y435,Y440,Y443-KHDRBS1 [nucleoplasm] (R-HSA-8848970) p-Y435,Y440,Y443-KHDRBS1 [cytosol] (R-HSA-8848995) KHDRBS1 [nucleoplasm] (R-HSA-8848941)	0.868	8
UniProt:P27986 PIK3R1	16	PIK3R1 [plasma membrane] (R-HSA-198365) PIK3R1 [cytosol] (R-HSA-74789) K63polyUb-PIK3R1 [cytosol] (R-HSA-3080572) PIK3R1 R574T [plasma membrane] (R-HSA-2399540) PIK3R1 R574I [plasma membrane] (R-HSA-2399536) PIK3R1 D560H [plasma membrane] (R-HSA-2399432) PIK3R1 N564K [plasma membrane] (R-HSA-2399431) PIK3R1 K459del [plasma membrane] (R-HSA-2399554) PIK3R1 N564D [plasma membrane] (R-HSA-2399427) PIK3R1 D560Y [plasma membrane] (R-HSA-2399421) PIK3R1 R574_T576del [plasma membrane] (R-HSA-2399544) PIK3R1 H450_E451del [plasma membrane] (R-HSA-2399545) PIK3R1 Y463_L466del [plasma membrane] (R-HSA-2399546) PIK3R1 K379E [plasma membrane] (R-HSA-8944148) PIK3R1 G376R [plasma membrane] (R-HSA-2399717) p-Y-PIK3R1 [cytosol] (R-HSA-9680647)	0.863	6
UniProt:Q8TF74 WIPF2	1	WIPF2 [cytosol] (R-HSA-2197666)	0.85	7
UniProt:P61978 HNRNPK	2	HNRNPK [nucleoplasm] (R-HSA-71945) polySUMO2-K422-HNRNPK [nucleoplasm] (R-HSA-4570532)	0.848	10
UniProt:Q9UKW4 VAV3	2	VAV3 [cytosol] (R-HSA-430152) p-Y173-VAV3 [cytosol] (R-HSA-442287)	0.848	8
UniProt:Q9H3S7 PTPN23	1	PTPN23 [nucleoplasm] (R-HSA-9008924)	0.834	8
UniProt:Q12774 ARHGEF5	1	ARHGEF5 [cytosol] (R-HSA-8873909)	0.82	8
UniProt:Q14185 DOCK1	1	DOCK1 [cytosol] (R-HSA-372654)	0.809	6
UniProt:P35235 Ptpn11	5	p-Y546,Y584-Shp2 [cytosol] (R-MMU-443116) Ptpn11 [cytosol] (R-MMU-210002) PTPN11 [nucleoplasm] (R-MMU-8937745) PTPN11 [cytosol] (R-MMU-162563) phospho-p-Y542,Y580-PTPN11 [cytosol] (R-MMU-162573)	0.809	7
UniProt:O43516 WIPF1	1	WIPF1 [cytosol] (R-HSA-201874)	0.804	5
UniProt:O00750 PIK3C2B	1	PIK3C2B [cytosol] (R-HSA-1604619)	0.802	6
UniProt:P42336 PIK3CA	20	PIK3CA H1047L [cytosol] (R-HSA-1500714) PIK3CA H1047R [cytosol] (R-HSA-1500716) PIK3CA [cytosol] (R-HSA-74787) PIK3CA R38C [cytosol] (R-HSA-1500691) PIK3CA R38G [cytosol] (R-HSA-2395950) PIK3CA R38S [cytosol] (R-HSA-2395947) PIK3CA R38H [cytosol] (R-HSA-1500718) PIK3CA E542Q [cytosol] (R-HSA-2328003) PIK3CA Q546P [cytosol] (R-HSA-1500695) PIK3CA Q546R [cytosol] (R-HSA-2362373) PIK3CA Q546H [cytosol] (R-HSA-2362374) PIK3CA E545G [cytosol] (R-HSA-1500709) PIK3CA Q546L [cytosol] (R-HSA-2362375) PIK3CA E542V [cytosol] (R-HSA-2328074) PIK3CA E545V [cytosol] (R-HSA-2362365) PIK3CA Q546E [cytosol] (R-HSA-2362383) PIK3CA E545Q [cytosol] (R-HSA-2362362) PIK3CA E545K [cytosol] (R-HSA-1500706) PIK3CA E545A [cytosol] (R-HSA-2362355) PIK3CA Q546K [cytosol] (R-HSA-1500705)	0.8	6
UniProt:Q6ZUJ8 PIK3AP1	1	p-4Y-PIK3AP1 [plasma membrane] (R-HSA-984814)	0.798	6
UniProt:Q9UKT9 IKZF3			0.795	8
UniProt:Q8N1K5 THMS1			0.794	11
UniProt:Q92918 M4K1			0.782	9
UniProt:O43150 ASAP2			0.752	4
UniProt:P10721 KIT	20	KIT C443Y [plasma membrane] (R-HSA-9680045) KIT T417_D419delinsY [plasma membrane] (R-HSA-9680110) KIT S476I [plasma membrane] (R-HSA-9680090) KIT K509I [plasma membrane] (R-HSA-9680177) KIT D419A [plasma membrane] (R-HSA-9680051) KIT D419del [plasma membrane] (R-HSA-9680079) KIT S501_A502dup [plasma membrane] (R-HSA-9680105) KIT D419G [plasma membrane] (R-HSA-9680057) KIT N505_F508dup [plasma membrane] (R-HSA-9680085) KIT C443S [plasma membrane] (R-HSA-9680038) KIT D419N [plasma membrane] (R-HSA-9680071) KIT S476N [plasma membrane] (R-HSA-9680097) KIT D419H [plasma membrane] (R-HSA-9680066) KIT V560_L576del [plasma membrane] (R-HSA-9670336) KIT Y823N [plasma membrane] (R-HSA-9669591) KIT Y823C [plasma membrane] (R-HSA-9669585) p6Y-KIT Y823D [plasma membrane] (R-HSA-9669628) p7Y-KIT D816V [plasma membrane] (R-HSA-9669612) p7Y-KIT K642E [plasma membrane] (R-HSA-9669596) p7Y-KIT N822K [plasma membrane] (R-HSA-9669617)	0.743	6
UniProt:Q8WV28 BLNK	2	BLNK [cytosol] (R-HSA-912750) p-5Y-BLNK [plasma membrane] (R-HSA-983579)	0.743	5
UniProt:Q8IUW3 SPA2L			0.742	5
UniProt:Q8N1I0 DOCK4	1	DOCK4 [cytosol] (R-HSA-1012995)	0.738	5
UniProt:P62993 GRB2	1	GRB2 [cytosol] (R-HSA-8983328)	0.738	5
UniProt:Q07912 TNK2	1	TNK2 [cytosol] (R-HSA-9842568)	0.737	5
UniProt:P35570 Irs1	7	Irs1 [cytosol] (R-RNO-1168867) phospho-Irs1 [plasma membrane] (R-RNO-2445090) Irs1 [plasma membrane] (R-RNO-2425392) p-Y-Irs1 [cytosol] (R-RNO-112362) Irs1 [cytosol] (R-RNO-74769) phospho-Irs1 [cytosol] (R-RNO-74772) phospho-Irs1 [plasma membrane] (R-RNO-198366)	0.737	5
UniProt:P21802 FGFR2	20	FGFR2 IIIa TM [extracellular region] (R-HSA-8851703) FGFR2 [plasma membrane] (R-HSA-2023840) FGFR2(22-767)-CCDC6(102-474) fusion [plasma membrane] (R-HSA-8853137) FGFR2(2-822)-CIT(927-2027) fusion [plasma membrane] (R-HSA-8853154) FGFR2(22-768)-BICC1(80-974) fusion [plasma membrane] (R-HSA-8853123) FGFR2(22-767)-AHCYL1(108-530) fusion [plasma membrane] (R-HSA-8853158) FGFR2(22-767)-OFD1(38-1012) fusion [plasma membrane] (R-HSA-8853150) FGFR2(22-767)-CASP7(1-303) fusion [plasma membrane] (R-HSA-8853153) FGFR2(22-767)-AFF3(292-1226) fusion [plasma membrane] (R-HSA-8853139) FGFR2(22-767)-CCAR(51-923) fusion [plasma membrane] (R-HSA-8853159) FGFR2 N549H [plasma membrane] (R-HSA-2033296) FGFR2 N549K [plasma membrane] (R-HSA-1637910) FGFR2 K660N [plasma membrane] (R-HSA-1637905) p-8Y-FGFR2 K660M [plasma membrane] (R-HSA-2033300) p-8Y-FGFR2 K660E [plasma membrane] (R-HSA-2033298) phosphorylated FGFR2 L764Hfs*4 [plasma membrane] (R-HSA-2071957) p-8Y-FGFR2 W290C [plasma membrane] (R-HSA-2029875) p-8Y-FGFR2 S267P [plasma membrane] (R-HSA-2029879) p-8Y-FGFR2 [plasma membrane] (R-HSA-2029874) p-8Y-FGFR2 N549K [plasma membrane] (R-HSA-2033306)	0.735	6
UniProt:A6NGB9 WIPF3	1	WIPF3 [cytosol] (R-HSA-2197670)	0.725	5
UniProt:Q96JJ3 ELMO2	1	ELMO2 [cytosol] (R-HSA-372642)	0.725	5
UniProt:Q96P48 ARAP1	2	ARAP1 [cytosol] (R-HSA-3211582) p-Y231-ARAP1 [cytosol] (R-HSA-8848869)	0.725	5
UniProt:B7ZLH0 B7ZLH0			0.718	6
UniProt:Q13444 ADAM15	1	ADAM15 [plasma membrane] (R-HSA-708329)	0.713	4
UniProt:Q14457 BECN1	4	BECN1 [cytosol] (R-HSA-1632841) p-S15-BECN1 [cytosol] (R-HSA-5682391) ISG15-K-BECN1 [cytosol] (R-HSA-9853030) K63polyUb-BECN1 [cytosol] (R-HSA-6782989)	0.709	8
UniProt:O43561 LAT	3	p-Y200,Y220-LAT [plasma membrane] (R-HSA-434829) LAT [plasma membrane] (R-HSA-202322) p-5Y-LAT [plasma membrane] (R-HSA-202364)	0.708	7
UniProt:Q62245 Sos1	4	phospho-Sos1 [cytosol] (R-MMU-109821) Sos1 [cytosol] (R-MMU-443318) Sos1 [plasma membrane] (R-MMU-983559) Sos1 [cytosol] (R-MMU-64847)	0.704	4
UniProt:Q08209 PPP3CA	2	PPP3CA [nucleoplasm] (R-HSA-2685599) PPP3CA [cytosol] (R-HSA-201771)	0.678	3
UniProt:P21860 ERBB3			0.678	5
UniProt:Q9H204 MED28	1	MED28 [nucleoplasm] (R-HSA-6804546)	0.676	3
UniProt:Q16643 DBN1	1	DBN1 [cytosol] (R-HSA-9714666)	0.674	4
UniProt:P11137 MTAP2			0.672	7
UniProt:O60636 TSN2			0.672	6
UniProt:Q8TBB1 LNX1	1	LNX1 [cytosol] (R-HSA-8851641)	0.666	4
UniProt:Q92569 PIK3R3	2	PIK3R3 [cytosol] (R-HSA-205223) K63polyUb-PIK3R3 [cytosol] (R-HSA-3080574)	0.666	4
UniProt:Q9H788 SH24A			0.666	4
UniProt:Q0VD86 INCA1			0.666	4
UniProt:Q06418 TYRO3			0.666	4
UniProt:Q9Y2W2 WBP11	1	WBP11 [nucleoplasm] (R-HSA-8867887)	0.666	4
UniProt:O14744 PRMT5	3	PRMT5 [cytosol] (R-HSA-191876) PRMT5 [nucleoplasm] (R-HSA-5205609) p-Y297,304,307-PRMT5 [nucleoplasm] (R-HSA-5211300)	0.666	4
UniProt:Q15427 SF3B4	1	SF3B4 [nucleoplasm] (R-HSA-71975)	0.665	3
UniProt:P15498 VAV1	5	VAV1 [plasma membrane] (R-HSA-1045153) VAV1 [cytosol] (R-HSA-195066) p-Y174-VAV1 [cytosol] (R-HSA-437946) p-Y142,Y160,Y174-VAV1 [plasma membrane] (R-HSA-389323) p-Y-VAV1 [cytosol] (R-HSA-9029087)	0.665	3
UniProt:P98078	3	Dab2 [cytosol] (R-MMU-8862456) Dab2 [lysosomal membrane] (R-MMU-2980807) Dab2 [plasma membrane] (R-MMU-2980808)	0.662	4
UniProt:O00459 PIK3R2	3	PIK3R2 [cytosol] (R-HSA-74791) K63polyUb-PIK3R2 [cytosol] (R-HSA-3080554) p-Y464-PIK3R2 [cytosol] (R-HSA-9860512)	0.659	4
UniProt:Q9Y5K6 CD2AP	1	CD2AP [cytosol] (R-HSA-373620)	0.659	3
UniProt:Q9Y2X7 GIT1	2	GIT1 [cytosol] (R-HSA-430326) p-Y383-GIT1 [cytosol] (R-HSA-3928463)	0.659	4
UniProt:Q05397 PTK2	11	p-6Y-PTK2 [cytosol] (R-HSA-354128) p-Y397-PTK2 [cytosol] (R-HSA-354068) PTK2 [cytosol] (R-HSA-201621) PTK2(1-772) [cytosol] (R-HSA-202827) PTK2(773-1052) [cytosol] (R-HSA-202829) p-5Y-PTK2 [cytosol] (R-HSA-5218711) p-5Y,S732-PTK2 [cytosol] (R-HSA-5229006) p-6Y,S732-PTK2 [cytosol] (R-HSA-5218694) pY-PTK2 [cytosol] (R-HSA-9632393) p-Y194,Y397-PTK2 [cytosol] (R-HSA-8874600) p-Y194,Y397,Y576,Y577-PTK2 [cytosol] (R-HSA-8874613)	0.659	4
UniProt:P11021 HSPA5	6	HSPA5 [lumenal side of endoplasmic reticulum membrane] (R-HSA-985498) HSPA5 [nucleoplasm] (R-HSA-5252042) HSPA5 [cytosol] (R-HSA-5252115) HSPA5 [endoplasmic reticulum membrane] (R-HSA-351315) HSPA5 [endoplasmic reticulum lumen] (R-HSA-387190) HSPA5 [extracellular region] (R-HSA-351322)	0.659	4
UniProt:P35579 MYH9	3	MYH9 [cytosol] (R-HSA-419173) MYH9(2-1644)-ALK(1067-1620) fusion [cytosol] (R-HSA-9715280) MYH9(2-1644)-p-7Y-ALK(1067-1620) fusion [cytosol] (R-HSA-9715279)	0.659	3
UniProt:Q13905 RAPGEF1	2	RAPGEF1 [cytosol] (R-HSA-913472) RAPGEF1 [endosome] (R-HSA-3008667)	0.658	3
UniProt:P27958 POLG	1	POLG [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HCV-8854138)	0.656	3
UniProt:P29350 PTPN6	5	PTPN6 [tertiary granule lumen] (R-HSA-6800952) PTPN6 [extracellular region] (R-HSA-6806315) PTPN6 [specific granule lumen] (R-HSA-6799641) PTPN6 [nucleoplasm] (R-HSA-9008911) PTPN6 [cytosol] (R-HSA-197938)	0.646	3
UniProt:Q9UQ16 DNM3	2	DNM3 [cytosol] (R-HSA-2213188) DNM3 [plasma membrane] (R-HSA-443610)	0.643	4
UniProt:Q9H7D0 DOCK5	1	DOCK5 [cytosol] (R-HSA-1012991)	0.643	4
UniProt:P23469 PTPRE			0.643	3
UniProt:Q9H9H4 VPS37B	1	VPS37B [endosome membrane] (R-HSA-184293)	0.643	4
UniProt:P42338 PIK3CB	1	PIK3CB [cytosol] (R-HSA-74788)	0.643	3
UniProt:Q9H792 PEAK1	1	PEAK1 [cytosol] (R-HSA-9715162)	0.643	3
UniProt:O43426 SYNJ1	1	SYNJ1 [cytosol] (R-HSA-1604634)	0.643	3
UniProt:Q75VX8 GARE2			0.643	3
UniProt:Q38SD2 LRRK1			0.643	3
UniProt:Q14247 CTTN	2	CTTN [cytosol] (R-HSA-201894) p-S113-CTTN [cytosol] (R-HSA-442842)	0.643	3
UniProt:P18031 PTPN1	2	PTPN1 [endosome membrane] (R-HSA-9815895) PTPN1 [cytosol] (R-HSA-210625)	0.642	4
UniProt:Q8N1K5-1 THEMIS			0.639	10
UniProt:O14939 PLD2	2	PLD2 [plasma membrane] (R-HSA-2029075) PLD2 [endoplasmic reticulum membrane] (R-HSA-1498791)	0.635	4
UniProt:Q15027 ACAP1			0.635	3
UniProt:P61981 YWHAG	1	YWHAG [cytosol] (R-HSA-380312)	0.615	4
UniProt:P06400 RB1	20	RB1 R661W [nucleoplasm] (R-HSA-9659801) RB1 C706F [nucleoplasm] (R-HSA-9659812) RB1 N480del [nucleoplasm] (R-HSA-9659792) RB1 C706Y [nucleoplasm] (R-HSA-9659821) RB1 R661Q [nucleoplasm] (R-HSA-9659807) RB1 I703_E737del [nucleoplasm] (R-HSA-9661065) RB1 R830_G887del [cytosol] (R-HSA-9661059) RB1 K791* [cytosol] (R-HSA-9662284) RB1 Q176* [cytosol] (R-HSA-9661774) RB1 S114* [cytosol] (R-HSA-9661775) RB1 K765* [cytosol] (R-HSA-9662281) RB1 W99* [cytosol] (R-HSA-9661769) RB1 S149* [cytosol] (R-HSA-9661770) RB1 E166* [cytosol] (R-HSA-9661767) RB1 G100* [cytosol] (R-HSA-9661763) RB1 E125* [cytosol] (R-HSA-9661784) RB1 Q121* [cytosol] (R-HSA-9661780) RB1 E184* [cytosol] (R-HSA-9661781) RB1 E137* [cytosol] (R-HSA-9661782) RB1 K745* [cytosol] (R-HSA-9662288)	0.61	4
UniProt:Q8NFH8 REPS2	1	REPS2 [cytosol] (R-HSA-432938)	0.602	8
UniProt:O14672 ADAM10	6	ADAM10(215-824) [plasma membrane] (R-HSA-179885) ADAM10 [plasma membrane] (R-HSA-157237) ADAM10 [endoplasmic reticulum lumen] (R-HSA-8956768) p-ADAM10 [endoplasmic reticulum lumen] (R-HSA-8956999) ADAM10 [specific granule membrane] (R-HSA-6799566) ADAM10 [tertiary granule membrane] (R-HSA-6800992)	0.602	5
UniProt:P34152 Ptk2	13	phospho-p-Y194,Y397,Y576,Y577-PTK2 [cytosol] (R-MMU-8874613) phospho-p-Y194,Y397-PTK2 [cytosol] (R-MMU-8874600) phospho-pY-PTK2 [cytosol] (R-MMU-9632393) p-Y428-FAK1 [cytosol] (R-MMU-3928397) Fak1 [cytosol] (R-MMU-3928448) phospho-p-6Y,S732-PTK2 [cytosol] (R-MMU-5218694) phospho-p-5Y,S732-PTK2 [cytosol] (R-MMU-5229006) phospho-p-5Y-PTK2 [cytosol] (R-MMU-5218711) PTK2(773-1052) [cytosol] (R-MMU-202829) PTK2(1-772) [cytosol] (R-MMU-202827) PTK2 [cytosol] (R-MMU-201621) phospho-p-Y397-PTK2 [cytosol] (R-MMU-354068) phospho-p-6Y-PTK2 [cytosol] (R-MMU-354128)	0.597	3
UniProt:P30530 AXL	2	p-Y779,Y821-AXL [plasma membrane] (R-HSA-5357460) AXL [plasma membrane] (R-HSA-197705)	0.597	4
UniProt:O15357 INPPL1	1	INPPL1 [cytosol] (R-HSA-913354)	0.597	4
UniProt:Q9ESJ4	1	Nckipsd [cytosol] (R-MMU-2197671)	0.593	8
UniProt:Q5SQ64 LY6G6F	2	LY6G6F [plasma membrane] (R-HSA-8862974) LY6G6F [platelet alpha granule membrane] (R-HSA-8862968)	0.591	3
UniProt:O43597 SPRY2	8	p-S112,S115-SPRY2 [cytosol] (R-HSA-1295619) SPRY2 [cytosol] (R-HSA-182949) SPRY2 [plasma membrane] (R-HSA-182924) p-S112,S121-SPRY2 [plasma membrane] (R-HSA-934595) p-Y55,Y227-SPRY2 [plasma membrane] (R-HSA-934555) p-S111,S120-SPRY2 [cytosol] (R-HSA-1295590) p-Y55,Y227-SPRY2 [plasma membrane] (R-HSA-1295629) p-Y55-SPRY2 [cytosol] (R-HSA-182950)	0.591	3
UniProt:O92972 POLG			0.589	2
UniProt:Q15303 ERBB4			0.573	7
UniProt:O14490 DLGAP1	1	DLGAP1 [plasma membrane] (R-HSA-6794239)	0.573	3
UniProt:Q9BYB0 SHANK3	1	SHANK3 [cytosol] (R-HSA-6794277)	0.573	2
UniProt:Q8IVH8 M4K3			0.573	2
UniProt:O15056 SYNJ2	1	SYNJ2 [cytosol] (R-HSA-1806193)	0.573	2
UniProt:P98082 DAB2	3	DAB2 [cytosol] (R-HSA-8862456) DAB2 [lysosomal membrane] (R-HSA-2980807) DAB2 [plasma membrane] (R-HSA-2980808)	0.573	2
UniProt:P55072 VCP	8	VCP [cytosol] (R-HSA-1181251) VCP [secretory granule lumen] (R-HSA-6801039) VCP [extracellular region] (R-HSA-6806191) VCP [azurophil granule lumen] (R-HSA-6800438) VCP [ficolin-1-rich granule lumen] (R-HSA-6800425) VCP [nucleoplasm] (R-HSA-5643745) VCP [endoplasmic reticulum membrane] (R-HSA-8943105) Me3K315-VCP [cytosol] (R-HSA-8932209)	0.57	3
UniProt:Q8TE12 LMX1A			0.57	3
UniProt:Q5BJH2-2 TMEM128			0.57	3
UniProt:Q9NPB6-2 PARD6A			0.57	3
UniProt:Q8WXH5 SOCS4	1	SOCS4 [cytosol] (R-HSA-8936109)	0.57	3
UniProt:Q07869 PPARA	2	PPARA [nucleoplasm] (R-HSA-400186) monoSUMO1-K185-PPARA [nucleoplasm] (R-HSA-4341099)	0.57	3
UniProt:P14868 DARS1	1	DARS [cytosol] (R-HSA-379605)	0.564	2
UniProt:O75369 FLNB	1	FLNB [cytosol] (R-HSA-354163)	0.564	2
UniProt:P19174 PLCG1	6	p-4Y-PLCG1 [plasma membrane] (R-HSA-167679) PLCG1 [cytosol] (R-HSA-202320) PLCG1 [plasma membrane] (R-HSA-167682) p-Y771,Y783,Y1254-PLCG1 [cytosol] (R-HSA-202357) p-Y771,Y783-PLCG1 [plasma membrane] (R-HSA-1169084) p-Y-PLCG1 [cytosol] (R-HSA-9029082)	0.564	2
UniProt:Q15109 AGER	1	AGER [plasma membrane] (R-HSA-197639)	0.564	2
UniProt:P21333 FLNA	3	FLNA [extracellular region] (R-HSA-350712) p-S2152-FLNA [cytosol] (R-HSA-5669246) FLNA [cytosol] (R-HSA-210019)	0.564	2
UniProt:Q9H0X6 RN208			0.556	3
UniProt:Q9BWF3-2 RBM4			0.556	3
UniProt:Q7Z783 Q7Z783			0.556	3
UniProt:Q13829 TNFAIP1	1	TNFAIP1 [cytosol] (R-HSA-9696531)	0.556	3
UniProt:Q6P1W5 CA094			0.556	3
UniProt:Q9P2A4 ABI3			0.556	3
UniProt:Q9NQC1-2 JADE2			0.556	3
UniProt:Q9UI10 EIF2B4	1	EIF2B4 [cytosol] (R-HSA-72521)	0.556	3
UniProt:A5D8V6 VPS37C	1	VPS37C [endosome membrane] (R-HSA-184438)	0.556	3
UniProt:Q15428 SF3A2	1	SF3A2 [nucleoplasm] (R-HSA-71964)	0.556	3
UniProt:Q9BRK4 LZTS2			0.556	3
UniProt:P52566 ARHGDIB	1	ARHGDIB [cytosol] (R-HSA-195081)	0.556	3
UniProt:Q04864 REL	2	REL [cytosol] (R-HSA-1168579) REL [nucleoplasm] (R-HSA-1168585)	0.556	3
UniProt:Q9BUN5-3 CCDC28B			0.556	3
UniProt:Q12929 EPS8	1	EPS8 [cytosol] (R-HSA-9662382)	0.556	3
UniProt:Q86UU5 GGN			0.556	3
UniProt:Q9BYN7 ZN341			0.556	3
UniProt:Q3LI72 KRTAP19-5	1	KRTAP19-5 [cytosol] (R-HSA-6810300)	0.556	3
UniProt:Q6DHY5 TBC3G			0.556	3
UniProt:P25791 LMO2	1	LMO2 [nucleoplasm] (R-HSA-8956513)	0.556	3
UniProt:Q8NFB2 T185A			0.556	3
UniProt:Q8IX15-3 HOMEZ			0.556	3
UniProt:Q6XD76 ASCL4			0.556	3
UniProt:P42681 TXK	3	TXK [cytosol] (R-HSA-3448733) p-Y91,Y420-TXK [cytosol] (R-HSA-3448740) p-Y420-TXK [cytosol] (R-HSA-3448734)	0.556	3
UniProt:O95994 AGR2			0.556	5
UniProt:A0JLT2-2 MED19			0.556	3
UniProt:Q92558 WASF1	3	WASF1 [cytosol] (R-HSA-200965) p-Y151-WASF1 [cytosol] (R-HSA-2029058) p-Y151,S,T-WASF1 [cytosol] (R-HSA-5672390)	0.556	3
UniProt:Q6ZU52 K0408			0.556	3
UniProt:Q8N4B1-4 PHETA1			0.556	3
UniProt:Q03989 ARI5A			0.556	3
UniProt:P27986-2 PIK3R1			0.556	3
UniProt:Q6UY14-3 ADAMTSL4			0.556	3
UniProt:Q6ZNG0 ZNF620	1	ZNF620 [nucleoplasm] (R-HSA-2127603)	0.556	3
UniProt:Q9Y330 ZBT12			0.556	5
UniProt:Q6IQ23-2 PLEKHA7			0.556	3
UniProt:Q8N9I9 DTX3			0.556	3
UniProt:Q86SG2 ANR23			0.556	3
UniProt:Q9BRR9 ARHGAP9	3	ARHGAP9 [cytosol] (R-HSA-2976572) ARHGAP9 [extracellular region] (R-HSA-6806529) ARHGAP9 [secretory granule lumen] (R-HSA-6804973)	0.556	3
UniProt:Q9HB07 MYG1			0.556	3
UniProt:Q9BRT8 ZNG1A			0.556	3
UniProt:Q9GZT8 NIF3L			0.556	3
UniProt:Q96D03 DDT4L			0.556	3
UniProt:A8MW99 MEI4			0.556	3
UniProt:B1AHC3 B1AHC3			0.556	3
UniProt:Q8N684-3 CPSF7			0.556	3
IntAct:EBI-22412087 CCSB ORF ID			0.556	3
IntAct:EBI-10220116 163154			0.556	3
IntAct:EBI-10178797 4005			0.556	3
UniProt:Q9UNY5 ZN232			0.556	3
UniProt:Q6S9Z5 ZN474			0.556	3
UniProt:Q96PV4 PNMA5			0.556	3
UniProt:O14512 SOCS7			0.556	3
UniProt:Q13625-3 TP53BP2			0.556	3
UniProt:Q13322-4 GRB10			0.556	3
UniProt:Q5JST6 EFHC2			0.556	3
UniProt:O15156 ZBT7B			0.556	3
UniProt:Q15907 RAB11B	3	RAB11B [recycling endosome membrane] (R-HSA-8854762) GGC-RAB11B [cytosol] (R-HSA-8873766) RAB11B [cytosol] (R-HSA-8873671)	0.556	3
UniProt:Q08117 TLE5	1	AES [nucleoplasm] (R-HSA-4648963)	0.556	3
UniProt:P14373 TRIM27	2	TRIM27 [cytosol] (R-HSA-8851002) TRIM27 [nucleoplasm] (R-HSA-2997690)	0.556	3
UniProt:Q9UIH9 KLF15	1	KLF15 [nucleoplasm] (R-HSA-8878735)	0.556	3
UniProt:Q96RU7 TRIB3	3	TRIB3 [plasma membrane] (R-HSA-199447) TRIB3 [cytosol] (R-HSA-162411) TRIB3 [nucleoplasm] (R-HSA-9635877)	0.556	3
UniProt:Q7L190 DPPA4	1	DPPA4 [nucleoplasm] (R-HSA-452999)	0.556	3
UniProt:Q9NRF2-2 SH2B1	1	SH2B1-2 [cytosol] (R-HSA-1675482)	0.556	3
UniProt:Q13352 ITGB3BP	2	ITGB3BP [nucleoplasm] (R-HSA-606325) ITGB3BP [cytosol] (R-HSA-3006405)	0.556	3
UniProt:Q14693 LPIN1	3	LPIN1 [endoplasmic reticulum membrane] (R-HSA-549157) LPIN1 [nuclear envelope] (R-HSA-4419927) p-S106-LPIN1 [nucleoplasm] (R-HSA-4419936)	0.556	3
UniProt:Q92841 DDX17	2	monoSUMO1-K50-DDX17 [nucleoplasm] (R-HSA-3900104) DDX17 [nucleoplasm] (R-HSA-3900090)	0.556	3
UniProt:P62324 BTG1	1	BTG1 [nucleoplasm] (R-HSA-9620886)	0.556	3
UniProt:P48634 PRC2A			0.553	2
UniProt:Q8WUM4 PDCD6IP	1	PDCD6IP [cytosol] (R-HSA-917717)	0.553	2
UniProt:Q09472 EP300	5	EP300 [nucleoplasm] (R-HSA-381325) p-S,T-EP300 [nucleoplasm] (R-HSA-8878072) FOXO4-S-S-EP300 [nucleoplasm] (R-HSA-9617691) Foxo4-S-S-EP300 [nucleoplasm] (R-HSA-9617720) monoSUMO1-K1020,1024-EP300 [nucleoplasm] (R-HSA-3899306)	0.553	2
UniProt:Q5JSH3 WDR44			0.547	2
UniProt:Q01082 SPTBN1	3	SPTBN1(2-159)-FLT3(570-993) fusion [cytosol] (R-HSA-9703316) SPTBN1(2-159)-p-6Y-FLT3(570-993) fusion [cytosol] (R-HSA-9703317) SPTBN1 [cytosol] (R-HSA-420048)	0.547	2
UniProt:P05787 KRT8	1	KRT8 [cytosol] (R-HSA-446043)	0.547	3
UniProt:Q92734 TFG	7	TFG [cytosol] (R-HSA-5688159) TFG(1-240)-ALK(1058-1620) fusion [cytosol] (R-HSA-9699806) TFG(1-138)-ALK(1058-1620) fusion [cytosol] (R-HSA-9699874) TFG(1-193)-ALK(1058-1620) fusion [cytosol] (R-HSA-9699887) TFG(1-193)-p-7Y-ALK(1058-1620) [cytosol] (R-HSA-9702029) TFG(1-240)-p-7Y-ALK(1058-1620) fusion [cytosol] (R-HSA-9702038) TFG(1-138)-p-7Y-ALK(1058-1620) fusion [cytosol] (R-HSA-9702019)	0.547	2
UniProt:O75083 WDR1	2	WDR1 [extracellular region] (R-HSA-350752) WDR1 [cytosol] (R-HSA-350699)	0.547	2
UniProt:Q06187 BTK	6	p-Y223,Y551-BTK [plasma membrane] (R-HSA-984807) p-Y551-BTK [plasma membrane] (R-HSA-9606165) BTK [cytosol] (R-HSA-197948) p-Y551-BTK [cytosol] (R-HSA-2685603) p-Y223,Y551-BTK [cytosol] (R-HSA-2424454) Active BTK [cytosol] (R-HSA-8964323)	0.547	2
UniProt:P19338 NCL	3	NCL [plasma membrane] (R-HSA-9836466) NCL [macropinosome membrane] (R-HSA-9837666) NCL [nucleoplasm] (R-HSA-6791213)	0.547	2
UniProt:O43295 SRGAP3	1	SRGAP3 [cytosol] (R-HSA-428463)	0.544	2
UniProt:Q9Y2R2 PTPN22	1	PTPN22 [cytosol] (R-HSA-8852205)	0.544	2
UniProt:P14618 PKM	3	PKM [ficolin-1-rich granule lumen] (R-HSA-6801387) PKM [extracellular region] (R-HSA-6806491) PKM [secretory granule lumen] (R-HSA-6801401)	0.527	2
UniProt:Q9UQ16-2 DNM3			0.527	2
UniProt:Q99816 TSG101	1	TSG101 [endosome membrane] (R-HSA-2980549)	0.527	3
UniProt:Q9UK41 VPS28	1	VPS28 [endosome membrane] (R-HSA-184342)	0.527	2
UniProt:P05141 SLC25A5	1	SLC25A5 [mitochondrial inner membrane] (R-HSA-49743)	0.527	3
UniProt:P27708 CAD	1	CAD [cytosol] (R-HSA-73452)	0.527	3
UniProt:O95789 ZMYM6			0.527	2
UniProt:Q93079 H2BC9	9	Ub-HIST1H2BH [nucleoplasm] (R-HSA-6782558) AcK-HIST1H2BH [nucleoplasm] (R-HSA-4549241) HIST1H2BH [extracellular region] (R-HSA-977580) AcK16-HIST1H2BH [nucleoplasm] (R-HSA-4568682) AcK6-HIST1H2BH [nucleoplasm] (R-HSA-4568718) AcK21-HIST1H2BH [nucleoplasm] (R-HSA-4568657) AcK13-HIST1H2BH [nucleoplasm] (R-HSA-4568705) Ub-121-HIST1H2BH [nucleoplasm] (R-HSA-3364021) HIST1H2BH [nucleoplasm] (R-HSA-181915)	0.527	2
UniProt:Q96EY5 MVB12A	1	MVB12A [endosome membrane] (R-HSA-8955360)	0.527	2
UniProt:Q9NZQ3 NCKIPSD	1	NCKIPSD [cytosol] (R-HSA-2197671)	0.527	2
UniProt:Q8TF42 UBS3B			0.527	3
UniProt:Q00325 S25A3			0.527	2
UniProt:Q96RF0 SNX18	1	SNX18 [cytosol] (R-HSA-8868038)	0.527	2
UniProt:Q96RF0-2 SNX18			0.527	2
UniProt:A5YM69 ARHGEF35	1	ARHGEF35 [cytosol] (R-HSA-8871615)	0.527	3
UniProt:Q13480-2 GAB1			0.527	2
UniProt:Q9H939 PPIP2			0.527	2
UniProt:P22626 HNRNPA2B1	2	HNRNPA2B1 [nucleoplasm] (R-HSA-71929) HNRNPA2B1 [extracellular exosome] (R-HSA-8950304)	0.527	2
UniProt:P62258 YWHAE	1	YWHAE [cytosol] (R-HSA-194368)	0.527	3
UniProt:P62805 H4C1	17	HIST1H4 [nucleoplasm] (R-HSA-181902) Me2K21-HIST1H4 [nucleoplasm] (R-HSA-5651652) MeK21-HIST1H4 [nucleoplasm] (R-HSA-5423110) AcK-HIST1H4 [nucleoplasm] (R-HSA-3451124) AcK9-HIST1H4 [nucleoplasm] (R-HSA-4568758) AcK6-HIST1H4 [nucleoplasm] (R-HSA-4568748) AcK17-HIST1H4 [nucleoplasm] (R-HSA-427469) HIST1H4A [extracellular region] (R-HSA-977569) Me3K21-HIST1H4 [nucleoplasm] (R-HSA-5651656) MeR4-HIST1H4 [nucleoplasm] (R-HSA-4754240) Me2sR4-HIST1H4 [nucleoplasm] (R-HSA-4754243) Me2aR4-HIST1H4 [nucleoplasm] (R-HSA-5229015) AcK13-HIST1H4 [nucleoplasm] (R-HSA-4568744) AcK5,12-HIST1H4A [nucleoplasm] (R-HSA-212078) 4xAcK-HIST1H4A [nucleoplasm] (R-HSA-427390) monoSUMO1-HIST1H4 [nucleoplasm] (R-HSA-4570518) polySUMO3-HIST1H4 [nucleoplasm] (R-HSA-4570531)	0.527	2
UniProt:P11142 HSPA8	10	HSPA8 [cytosol] (R-HSA-264476) HSPA8 [lysosomal lumen] (R-HSA-9625182) HSPA8 [late endosome lumen] (R-HSA-9631104) HSPA8 [clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane] (R-HSA-888599) HSPA8 [plasma membrane] (R-HSA-936508) HSPA8 [nucleoplasm] (R-HSA-5082380) HSPA8 [secretory granule lumen] (R-HSA-6801530) HSPA8 [extracellular region] (R-HSA-6805936) HSPA8 [ficolin-1-rich granule lumen] (R-HSA-6801494) Me3K561-HSPA8 [nucleoplasm] (R-HSA-8932217)	0.527	3
UniProt:P07355 ANXA2	6	ANXA2 [azurophil granule lumen] (R-HSA-6798766) ANXA2 [extracellular region] (R-HSA-6806242) p-S26-ANXA2 [cytosol] (R-HSA-9865163) p-Y24,S26-ANXA2 [cytosol] (R-HSA-9865224) ANXA2 [external side of plasma membrane] (R-HSA-5336164) ANXA2 [cytosol] (R-HSA-5263667)	0.527	2
UniProt:P62937 PPIA	5	PPIA [extracellular exosome] (R-HSA-6801538) PPIA [ficolin-1-rich granule lumen] (R-HSA-6801391) PPIA [extracellular region] (R-HSA-173646) PPIA [secretory granule lumen] (R-HSA-6801400) PPIA [cytosol] (R-HSA-173123)	0.527	2
UniProt:P63104 YWHAZ	2	YWHAZ [cytosol] (R-HSA-206099) YWHAZ [nucleoplasm] (R-HSA-450469)	0.527	3
UniProt:P12236 SLC25A6	2	SLC25A6 [mitochondrial intermembrane space] (R-HSA-1955374) SLC25A6 [mitochondrial inner membrane] (R-HSA-49745)	0.527	2
UniProt:P04792 HSBP1	3	HSPB1 [cytosol] (R-HSA-450563) p-S15,S78,S82-HSP27 [cytosol] (R-HSA-5218697) p-S78,S82 HSPB1 [cytosol] (R-HSA-5687009)	0.527	3
UniProt:Q9Y230 RUVBL2	1	RUVBL2 [nucleoplasm] (R-HSA-418321)	0.527	2
UniProt:P52952 NKX2-5	1	NKX2-5 [nucleoplasm] (R-HSA-4005994)	0.527	2
UniProt:P31946 YWHAB	1	YWHAB [cytosol] (R-HSA-48888)	0.527	3
UniProt:Q9Y265 RUVBL1	1	RUVBL1 [nucleoplasm] (R-HSA-418323)	0.527	2
UniProt:P13639 EEF2	10	EEF2 [secretory granule lumen] (R-HSA-6801504) EEF2 [extracellular region] (R-HSA-6806499) EEF2 [ficolin-1-rich granule lumen] (R-HSA-6801513) EEF2 [cytosol] (R-HSA-156901) aminocarboxypropyl EEF2 [cytosol] (R-HSA-5358478) Me-diphthine EEF2 [cytosol] (R-HSA-5367025) nascent EEF2 [cytosol] (R-HSA-5358472) diphthine EEF2 [cytosol] (R-HSA-5358501) ADP-ribo-EEF2 [cytosol] (R-HSA-5334764) Me3K525-EEF2 [cytosol] (R-HSA-8932237)	0.527	2
UniProt:P41240 CSK	2	CSK [cytosol] (R-HSA-203776) CSK [plasma membrane] (R-HSA-180499)	0.527	2
UniProt:P19105 MYL12A	2	p-S19-MYL12A [cytosol] (R-HSA-390749) MYL12A [cytosol] (R-HSA-390735)	0.527	2
UniProt:P29353-1 SHC1	4	SHC1-1 [cytosol] (R-HSA-1433366) SHC1 [plasma membrane] (R-HSA-2404179) p-S139,3Y-SHC1-1 [cytosol] (R-HSA-8934452) p-Y349,Y350,Y427-SHC1-1 [cytosol] (R-HSA-2404176)	0.524	3
UniProt:P26662-PRO_0000037647			0.524	3
UniProt:O75674 TM1L1			0.524	2
UniProt:Q7L0Q8 RHOU	4	p-Y254-RHOU [endosome membrane] (R-HSA-9726860) p-Y254-RHOU [plasma membrane] (R-HSA-9726857) RHOU [plasma membrane] (R-HSA-194914) RHOU [cytosol] (R-HSA-194901)	0.524	3
UniProt:Q13177 PAK2	11	p-S141,T402-PAK2 [cytosol] (R-HSA-399824) PAK2 [cytosol] (R-HSA-211604) p-5S-PAK2 [cytosol] (R-HSA-211609) PAK2(213-524) [cytosol] (R-HSA-211653) p-5S-PAK2(2-212) [cytosol] (R-HSA-211588) p-T402-PAK2(213-524) [cytosol] (R-HSA-211654) p-T402-PAK2(213-524) [nucleoplasm] (R-HSA-211709) K48polyUb-p-T402-PAK-2p43 [cytosol] (R-HSA-3095873) p-Y130,S141,T402-PAK2 [cytosol] (R-HSA-5218705) PAK2(1-524) [plasma membrane] (R-HSA-164946) p-S141,T402-PAK2 [plasma membrane] (R-HSA-5096524)	0.524	2
UniProt:Q5SXH7-1 PLEKHS1			0.508	2
UniProt:Q66PJ3-4 ARL6IP4			0.508	2
UniProt:Q9Y478 PRKAB1	2	PRKAB1 [cytosol] (R-HSA-380968) PRKAB1 [nucleoplasm] (R-HSA-2151199)	0.508	2
UniProt:Q16236 NFE2L2	13	p-S40-NFE2L2 [nucleoplasm] (R-HSA-9715109) p-S,T-NFE2L2 [nucleoplasm] (R-HSA-9715110) p-S40-NFE2L2 [cytosol] (R-HSA-8932290) p-S,T-NFE2L2 [cytosol] (R-HSA-8932311) NFE2L2 [cytosol] (R-HSA-201566) p-S,T-18 AcK-NFE2L2 [nucleoplasm] (R-HSA-9760033) p-S40-18 AcK-NFE2L2 [nucleoplasm] (R-HSA-9760018) ub-NFE2L2 [cytosol] (R-HSA-9758077) ub-p-S335, S338,T-NFE2L2 [nucleoplasm] (R-HSA-9762055) ub-p-S40, S335, S338- NFE2L2 [nucleoplasm] (R-HSA-9762058) p-S344, S347,T-NFE2L2 [nucleoplasm] (R-HSA-9762048) p-S40, S344, S347- NFE2L2 [nucleoplasm] (R-HSA-9762050) p-S,T,S558-NFE2L2 [nucleoplasm] (R-HSA-9795736)	0.508	2
UniProt:P54762 EPHB1	6	p-Y594,Y600-EPHB1 [plasma membrane] (R-HSA-3928347) EPHB1 [plasma membrane] (R-HSA-2682340) EPHB1 (18-?) [extracellular region] (R-HSA-3928393) EPHB1 (?-984) [plasma membrane] (R-HSA-3928402) EPHB1 (?-984) [cytosol] (R-HSA-3928438) EPHB1 (?-?) [plasma membrane] (R-HSA-3928449)	0.499	2
UniProt:Q810M5 ZDH19			0.499	2
UniProt:Q7VLE8 Q7VLE8			0.499	2
UniProt:Q8N7B6-2 PACRGL			0.488	2
UniProt:Q9H7T9 AUNIP			0.488	2
UniProt:Q96D37 Q96D37			0.488	2
UniProt:Q5T749 KPRP	1	KPRP [cytosol] (R-HSA-9839614)	0.488	2
UniProt:Q9NP98 MYOZ1			0.488	2
UniProt:Q9Y5E4 PCDB5			0.488	2
UniProt:Q96ID7 Q96ID7			0.488	2
UniProt:Q9BRT2 UQCC2	1	UQCC2 [mitochondrial inner membrane] (R-HSA-9865900)	0.488	2
UniProt:Q8IZQ1 WDFY3			0.488	2
UniProt:Q96SW2-2 CRBN			0.488	2
UniProt:Q8N448 LNX2			0.488	2
UniProt:O14641 DVL2	5	DVL2 [cytosol] (R-HSA-201694) pp-DVL2 [cytosol] (R-HSA-3772398) p-DVL2 [cytosol] (R-HSA-201706) p-DVL2 [clathrin-coated endocytic vesicle] (R-HSA-5138444) ub-DVL2 [cytosol] (R-HSA-4652689)	0.488	2
UniProt:P26196 DDX6	1	DDX6 [cytosol] (R-HSA-430032)	0.483	2
UniProt:P09619 PDGFRB	3	p-12Y-PDGFRB [plasma membrane] (R-HSA-186803) PDGFRB [plasma membrane] (R-HSA-186767) p-11Y-PDGFRB [plasma membrane] (R-HSA-8864039)	0.462	2
UniProt:P12497-PRO_0000042399 GAG-POL			0.462	3
UniProt:A9UF07 A9UF07			0.462	6
UniProt:P40763 STAT3	12	p-Y705-STAT3 [nucleoplasm] (R-HSA-1112554) p-Y705-STAT3 [cytosol] (R-HSA-914048) STAT3 [cytosol] (R-HSA-539044) p-Y705-STAT3 [cytosol] (R-HSA-8983130) p-Y705,S727-STAT3 [cytosol] (R-HSA-539048) p-S727-STAT3 [cytosol] (R-HSA-198705) p-Y705-STAT3 [nucleoplasm] (R-HSA-9027589) p-Y705,S727-STAT3 [nucleoplasm] (R-HSA-9701429) AcK685- p-Y705,S727-STAT3 [nucleoplasm] (R-HSA-9701435) p-STAT3 [cytosol] (R-HSA-8982823) p-STAT3 [nucleoplasm] (R-HSA-8983188) Unfolded STAT3 [cytosol] (R-HSA-6813811)	0.462	3

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