Reactome | p-Y701-STAT1 binds p-Y705-STAT3

p-Y701-STAT1 binds p-Y705-STAT3

Stable Identifier

R-HSA-8985966

Type

Reaction [binding]

Species

Homo sapiens

Compartment

cytosol

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Signal transducer and activator of transcription 1-alpha/beta (STAT1) and STAT3 dimerize.

Following IL9 induced STAT activation, heterodimers of tyrosine phosphorylated STAT1:STAT3 have been identified (Bauer et al. 1998).

Literature References

PubMed ID	Title	Journal	Year
9535918	Heteromerization of the gammac chain with the interleukin-9 receptor alpha subunit leads to STAT activation and prevention of apoptosis Bauer, JH, Liu, KD, You, Y, Lai, SY, Goldsmith, MA	J. Biol. Chem.	1998