Reactome | p-Y701-STAT1 binds p-Y705-STAT3

p-Y701-STAT1 binds p-Y705-STAT3

Stable Identifier

R-HSA-8985966

Type

Reaction [binding]

Species

Homo sapiens

Compartment

cytosol

Locations in the PathwayBrowser

Expand all

General

SBML | | PDF

SVG | | PPTX | SBGN

Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

Signal transducer and activator of transcription 1-alpha/beta (STAT1) and STAT3 dimerize.

Following IL9 induced STAT activation, heterodimers of tyrosine phosphorylated STAT1:STAT3 have been identified (Bauer et al. 1998).

Literature References

PubMed ID	Title	Journal	Year
9535918	Heteromerization of the gammac chain with the interleukin-9 receptor alpha subunit leads to STAT activation and prevention of apoptosis You, Y, Bauer, JH, Lai, SY, Liu, KD, Goldsmith, MA	J. Biol. Chem.	1998