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SIN3A:HDAC1:HDAC2 [nucleoplasm]
Stable Identifier
R-HSA-9005991
Type
Complex
Species
Homo sapiens
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
Gene expression (Transcription) (Homo sapiens)
RNA Polymerase II Transcription (Homo sapiens)
Generic Transcription Pathway (Homo sapiens)
FOXO-mediated transcription (Homo sapiens)
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes (Homo sapiens)
FOXO1 and SIN3A:HDAC complex bind GCK gene promoter (Homo sapiens)
FOXO1:SIN3A:HDAC1.HDAC2 dimers:GCK gene [nucleoplasm] (Homo sapiens)
FOXO1:SIN3A:HDAC1,HDAC2 dimers [nucleoplasm] (Homo sapiens)
SIN3A:HDAC1,HDAC2 dimers [nucleoplasm] (Homo sapiens)
SIN3A:HDAC1:HDAC2 [nucleoplasm] (Homo sapiens)
SIN3A:HDAC1,HDAC2 dimers [nucleoplasm] (Homo sapiens)
SIN3A:HDAC1:HDAC2 [nucleoplasm] (Homo sapiens)
GCK gene expression is inhibited by FOXO1, SIN3A and HDACs (Homo sapiens)
FOXO1:SIN3A:HDAC1,HDAC2 dimers [nucleoplasm] (Homo sapiens)
SIN3A:HDAC1,HDAC2 dimers [nucleoplasm] (Homo sapiens)
SIN3A:HDAC1:HDAC2 [nucleoplasm] (Homo sapiens)
FOXO1:SIN3A:HDAC1.HDAC2 dimers:GCK gene [nucleoplasm] (Homo sapiens)
FOXO1:SIN3A:HDAC1,HDAC2 dimers [nucleoplasm] (Homo sapiens)
SIN3A:HDAC1,HDAC2 dimers [nucleoplasm] (Homo sapiens)
SIN3A:HDAC1:HDAC2 [nucleoplasm] (Homo sapiens)
Transcriptional Regulation by MECP2 (Homo sapiens)
MECP2 regulates neuronal receptors and channels (Homo sapiens)
GRIA2 gene expression is inhibited by MECP2:SIN3A complex (Homo sapiens)
MECP2:SIN3A:HDAC1:HDAC2 [nucleoplasm] (Homo sapiens)
SIN3A:HDAC1:HDAC2 [nucleoplasm] (Homo sapiens)
MECP2:SIN3A:HDAC1:HDAC2:GRIA2 gene [nucleoplasm] (Homo sapiens)
MECP2:SIN3A:HDAC1:HDAC2 [nucleoplasm] (Homo sapiens)
SIN3A:HDAC1:HDAC2 [nucleoplasm] (Homo sapiens)
MECP2:SIN3A complex binds GRIA2 gene promoter (Homo sapiens)
MECP2:SIN3A:HDAC1:HDAC2 [nucleoplasm] (Homo sapiens)
SIN3A:HDAC1:HDAC2 [nucleoplasm] (Homo sapiens)
MECP2:SIN3A:HDAC1:HDAC2:GRIA2 gene [nucleoplasm] (Homo sapiens)
MECP2:SIN3A:HDAC1:HDAC2 [nucleoplasm] (Homo sapiens)
SIN3A:HDAC1:HDAC2 [nucleoplasm] (Homo sapiens)
MECP2:SIN3A complex binds OPRM1 gene promoter (Homo sapiens)
MECP2:SIN3A:HDAC1:HDAC1:OPRM1 gene [nucleoplasm] (Homo sapiens)
MECP2:SIN3A:HDAC1:HDAC2 [nucleoplasm] (Homo sapiens)
SIN3A:HDAC1:HDAC2 [nucleoplasm] (Homo sapiens)
MECP2:SIN3A:HDAC1:HDAC2 [nucleoplasm] (Homo sapiens)
SIN3A:HDAC1:HDAC2 [nucleoplasm] (Homo sapiens)
OPRM1 gene expression is repressed by MECP2 (Homo sapiens)
MECP2:SIN3A:HDAC1:HDAC1:OPRM1 gene [nucleoplasm] (Homo sapiens)
MECP2:SIN3A:HDAC1:HDAC2 [nucleoplasm] (Homo sapiens)
SIN3A:HDAC1:HDAC2 [nucleoplasm] (Homo sapiens)
MECP2:SIN3A:HDAC1:HDAC2 [nucleoplasm] (Homo sapiens)
SIN3A:HDAC1:HDAC2 [nucleoplasm] (Homo sapiens)
MECP2 regulates transcription of neuronal ligands (Homo sapiens)
BDNF gene transcription (Homo sapiens)
MECP2:SIN3A:HDAC1:HDAC2 [nucleoplasm] (Homo sapiens)
SIN3A:HDAC1:HDAC2 [nucleoplasm] (Homo sapiens)
Regulation of MECP2 expression and activity (Homo sapiens)
MECP2 binds the SIN3A co-repressor complex (Homo sapiens)
MECP2:SIN3A:HDAC1,HDAC2 [nucleoplasm] (Homo sapiens)
MECP2:SIN3A:HDAC1:HDAC2 [nucleoplasm] (Homo sapiens)
SIN3A:HDAC1:HDAC2 [nucleoplasm] (Homo sapiens)
SIN3A:HDAC1,HDAC2 dimers [nucleoplasm] (Homo sapiens)
SIN3A:HDAC1:HDAC2 [nucleoplasm] (Homo sapiens)
Literature References
PubMed ID
Title
Journal
Year
9620804
Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex
Ng, HH
,
Nan, X
,
Bird, A
,
Turner, BM
,
Eisenman, RN
,
Laherty, CD
,
Johnson, CA
Nature
1998
Participants
components
HDAC1:HDAC2 [nucleoplasm]
(Homo sapiens)
SIN3A [nucleoplasm]
(Homo sapiens)
Participates
as a member of
SIN3A:HDAC1,HDAC2 dimers [nucleoplasm] (Homo sapiens)
as a component of
MECP2:SIN3A:HDAC1:HDAC2 [nucleoplasm] (Homo sapiens)
Inferred To
SIN3A:HDAC1:HDAC2 [nucleoplasm]
(Bos taurus)
SIN3A:HDAC1:HDAC2 [nucleoplasm]
(Caenorhabditis elegans)
SIN3A:HDAC1:HDAC2 [nucleoplasm]
(Canis familiaris)
SIN3A:HDAC1:HDAC2 [nucleoplasm]
(Dictyostelium discoideum)
SIN3A:HDAC1:HDAC2 [nucleoplasm]
(Drosophila melanogaster)
SIN3A:HDAC1:HDAC2 [nucleoplasm]
(Gallus gallus)
SIN3A:HDAC1:HDAC2 [nucleoplasm]
(Mus musculus)
SIN3A:HDAC1:HDAC2 [nucleoplasm]
(Rattus norvegicus)
SIN3A:HDAC1:HDAC2 [nucleoplasm]
(Saccharomyces cerevisiae)
SIN3A:HDAC1:HDAC2 [nucleoplasm]
(Schizosaccharomyces pombe)
SIN3A:HDAC1:HDAC2 [nucleoplasm]
(Sus scrofa)
SIN3A:HDAC1:HDAC2 [nucleoplasm]
(Xenopus tropicalis)
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