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E2F6:(TFDP1,TFDP2):RAD51 gene [nucleoplasm]
Stable Identifier
R-HSA-9007547
Type
Complex
Species
Homo sapiens
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
Gene expression (Transcription) (Homo sapiens)
RNA Polymerase II Transcription (Homo sapiens)
Generic Transcription Pathway (Homo sapiens)
Transcriptional Regulation by E2F6 (Homo sapiens)
E2F6 binds RAD51 gene promoter (Homo sapiens)
E2F6:(TFDP1,TFDP2):RAD51 gene [nucleoplasm] (Homo sapiens)
RAD51 gene expression is stimulated by E2F1 and inhibited by E2F6 (Homo sapiens)
E2F6:(TFDP1,TFDP2):RAD51 gene [nucleoplasm] (Homo sapiens)
Literature References
PubMed ID
Title
Journal
Year
23954429
Chk1 inhibits E2F6 repressor function in response to replication stress to maintain cell-cycle transcription
Bertoli, C
,
McGowan, C
,
Klier, S
,
Wittenberg, C
,
de Bruin, RA
Curr. Biol.
2013
Participants
components
E2F6:(TFDP1,TFDP2) [nucleoplasm]
(Homo sapiens)
RAD51 gene [nucleoplasm]
(Homo sapiens)
Participates
as an output of
E2F6 binds RAD51 gene promoter (Homo sapiens)
This entity regulates
Negatively
RAD51 gene expression is stimulated by E2F1 and inhibited by E2F6
(Homo sapiens)
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