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E2F6 binds RBBP8 gene promoter
Stable Identifier
R-HSA-9007615
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
Locations in the PathwayBrowser
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Gene expression (Transcription) (Homo sapiens)
RNA Polymerase II Transcription (Homo sapiens)
Generic Transcription Pathway (Homo sapiens)
Transcriptional Regulation by E2F6 (Homo sapiens)
E2F6 binds RBBP8 gene promoter (Homo sapiens)
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
E2F6, presumably in complex with at least TFDP1 (DP-1) or TFDP2 (DP-2), binds the promoter of the RBBP8 (CtIP) gene (Oberley et al. 2003).
Literature References
PubMed ID
Title
Journal
Year
12909625
E2F6 negatively regulates BRCA1 in human cancer cells without methylation of histone H3 on lysine 9
Inman, DR
,
Oberley, MJ
,
Farnham, PJ
J. Biol. Chem.
2003
Participants
Input
E2F6:(TFDP1,TFDP2) [nucleoplasm]
(Homo sapiens)
RBBP8 gene [nucleoplasm]
(Homo sapiens)
Output
E2F6:(TFDP1.TFDP2):RBBP8 gene [nucleoplasm]
(Homo sapiens)
Participates
as an event of
Transcriptional Regulation by E2F6 (Homo sapiens)
Authored
Orlic-Milacic, M (2017-06-01)
Reviewed
Herlihy, A (2017-05-12)
Created
Orlic-Milacic, M (2017-05-31)
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