Reactome | TSPAN15 [endoplasmic reticulum lumen]

TSPAN15 [endoplasmic reticulum lumen]

Stable Identifier

R-HSA-9010117

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endoplasmic reticulum lumen

Synonyms

Tetraspanin-15, TSN15_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:O95858 TSPAN15

Gene Names

TSPAN15, NET7, TM4SF15, UNQ677/PRO1311

Chain

chain:1-294

Reference Genes

BioGPS Gene:23555 TSPAN15

COSMIC (genes):TSPAN15 TSPAN15

CTD Gene:23555 TSPAN15

dbSNP Gene:23555 TSPAN15

ENSEMBL:ENSG00000099282 TSPAN15

ENSEMBL_homo_sapiens_GENE:ENSG00000099282.10 TSPAN15

HGNC:23298 TSPAN15

KEGG Gene (Homo sapiens):23555 TSPAN15

Monarch:23555 TSPAN15

NCBI Gene:23555 TSPAN15

OMIM:613140 TSPAN15

UCSC:O95858 TSPAN15

Reference Transcript

RefSeq:NM_012339.3 TSPAN15

Other Identifiers

11752612_at

16705620

218693_PM_at

218693_at

23555

3250374

3250375

3250387

3250388

3250391

3250402

3250403

3250408

3250410

3250412

3250413

3250414

48744_g_at

48746_at

7928046

A_32_P7015

GE54832

GO:0005515

GO:0005634

GO:0005654

GO:0005768

GO:0005783

GO:0005788

GO:0005829

GO:0005886

GO:0009986

GO:0016020

GO:0016604

GO:0019899

GO:0023052

GO:0030054

GO:0030163

GO:0031410

GO:0031902

GO:0043226

GO:0043231

GO:0045746

GO:0051043

GO:0051604

GO:0072659

GO:0097197

HMNXSV003057518

ILMN_1803850

PH_hs_0031422

TC10000420.hg

g6912529_3p_at

Participates

as a member of

TSPANs [endoplasmic reticulum lumen] (Homo sapiens)

Other forms of this molecule

TSPAN15 [plasma membrane]

Cross References

RefSeq

NP_036471.1

OpenTargets

ENSG00000099282

GeneCards

O95858

HPA

ENSG00000099282-TSPAN15

Ensembl

ENSP00000362387, ENSG00000099282, ENST00000373290

PRO

O95858

Pharos - Targets

O95858

PDB

7RD5, 7RDB, 8ESV

Interactors (10)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O14672 ADAM10	6	ADAM10(215-824) [plasma membrane] (R-HSA-179885) ADAM10 [plasma membrane] (R-HSA-157237) ADAM10 [endoplasmic reticulum lumen] (R-HSA-8956768) p-ADAM10 [endoplasmic reticulum lumen] (R-HSA-8956999) ADAM10 [tertiary granule membrane] (R-HSA-6800992) ADAM10 [specific granule membrane] (R-HSA-6799566)	0.799	11
UniProt:P43657 LPAR6	1	LPAR6 [plasma membrane] (R-HSA-417913)	0.527	2
UniProt:Q9H244 P2RY12	1	P2RY12 [plasma membrane] (R-HSA-391959)	0.527	2
UniProt:Q9H8X2 IPPK	2	IPPK [cytosol] (R-HSA-1604598) IPPK [nucleoplasm] (R-HSA-2023949)	0.527	2
UniProt:P30825 SLC7A1	1	SLC7A1 [plasma membrane] (R-HSA-375771)	0.527	3
UniProt:P48960 ADGRE5	2	CD97 [plasma membrane] (R-HSA-444764) CD97(21-835) [secretory granule membrane] (R-HSA-6803297)	0.527	4
UniProt:Q16581 C3AR1	3	C3AR1 [plasma membrane] (R-HSA-444727) C3AR1 [azurophil granule membrane] (R-HSA-6799517) C3AR1 [specific granule membrane] (R-HSA-6799516)	0.527	2
UniProt:Q12846 STX4	4	STX4 [plasma membrane] (R-HSA-181519) STX4 [phagocytic vesicle membrane] (R-HSA-2029044) STX4 [cytosol] (R-HSA-114505) p-STX4 [cytosol] (R-HSA-114681)	0.527	2
UniProt:P25103 TACR1	2	TACR1 [clathrin-coated endocytic vesicle membrane] (R-HSA-8869122) TACR1 [plasma membrane] (R-HSA-380103)	0.527	2
UniProt:P21926 CD9	4	CD9 [plasma membrane] (R-HSA-51717) CD9 [endocytic vesicle membrane] (R-HSA-5334774) CD9 [clathrin-coated endocytic vesicle membrane] (R-HSA-5334779) CD9 [platelet alpha granule membrane] (R-HSA-114585)	0.462	2

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