Reactome | MLEC [endoplasmic reticulum membrane]

MLEC [endoplasmic reticulum membrane]

Stable Identifier

R-HSA-901082

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endoplasmic reticulum membrane

Synonyms

Malectin, MLEC_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q14165 MLEC

Gene Names

MLEC, KIAA0152

Chain

signal peptide:1-28, chain:29-292

Reference Genes

BioGPS Gene:9761 MLEC

COSMIC (genes):MLEC MLEC

CTD Gene:9761 MLEC

dbSNP Gene:9761 MLEC

ENSEMBL:ENSG00000110917 MLEC

HGNC:28973 MLEC

KEGG Gene (Homo sapiens):9761 MLEC

Monarch:9761 MLEC

NCBI Gene:9761 MLEC

OMIM:613802 MLEC

UCSC:Q14165 MLEC

Reference Transcript

RefSeq:NM_014730.3 MLEC

Other Identifiers

0005050731

11715518_a_at

11715519_a_at

11715520_at

11715521_a_at

16757969

200616_PM_s_at

200616_s_at

200617_PM_at

200617_at

243545_PM_at

243545_at

3434528

3434529

3434530

3434531

3434537

3434538

3434539

3434541

3434542

3434543

3434544

3434545

3434546

3434547

3434548

3434549

3434550

3434551

3434553

3434555

3434557

41728_at

7959205

9761

A_14_P110817

A_23_P2554

A_24_P304449

D63486_at

GE62497

GO:0003674

GO:0005515

GO:0005575

GO:0005622

GO:0005737

GO:0005783

GO:0005789

GO:0005886

GO:0005975

GO:0006464

GO:0006487

GO:0008150

GO:0008250

GO:0009058

GO:0016020

GO:0016021

GO:0019899

GO:0030246

GO:0031410

GO:0032991

GO:0035579

GO:0043226

HMNXSV003032241

HMNXSV003034664

Hs.201789.0.A1_3p_at

ILMN_1657495

ILMN_3243381

PH_hs_0010734

TC12000949.hg

g12653206_3p_a_at

g7661947_3p_at

Participates

as an output of

Removal of the second glucose by glucosidase II (Homo sapiens)

as a component of

unfolded protein:(Glc)2 (GlcNAc)2 (Man)9 (Asn)1:malectin [endoplasmic reticulum lumen] (Homo sapiens)

as an input of

Binding of Malectin (Homo sapiens)

Other forms of this molecule

MLEC [plasma membrane]

MLEC [specific granule membrane]

Inferred To

MLEC [endoplasmic reticulum membrane] (Bos taurus)

MLEC [endoplasmic reticulum membrane] (Caenorhabditis elegans)

MLEC [endoplasmic reticulum membrane] (Canis familiaris)

MLEC [endoplasmic reticulum membrane] (Gallus gallus)

mlec [endoplasmic reticulum membrane] (Danio rerio)

mlec [endoplasmic reticulum membrane] (Xenopus tropicalis)

Dmel\CG9257 [endoplasmic reticulum membrane] (Drosophila melanogaster)

CABP1 [endoplasmic reticulum membrane] (Sus scrofa)

Mlec [endoplasmic reticulum membrane] (Mus musculus)

Mlec [endoplasmic reticulum membrane] (Rattus norvegicus)

Cross References

RefSeq

NP_055545.1

OpenTargets

ENSG00000110917

GeneCards

Q14165

HPA

ENSG00000110917-MLEC

Ensembl

ENSP00000228506, ENSG00000110917, ENST00000228506

PRO

Q14165

Pharos - Targets

Q14165

PDB

6S7T

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P04843 RPN1	1	RPN1 [endoplasmic reticulum membrane] (R-HSA-264994)	0.589	2
UniProt:P04844 RPN2	1	RPN2 [endoplasmic reticulum membrane] (R-HSA-264937)	0.564	2
UniProt:Q8TCJ2 STT3B			0.534	2