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LHX2 [nucleoplasm]
Stable Identifier
R-HSA-9011100
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
LIM/homeobox protein Lhx2, LHX2_HUMAN
Locations in the PathwayBrowser for interactor UniProt:A7KAX9 ARHGAP32
Expand all
Developmental Biology (Homo sapiens)
Nervous system development (Homo sapiens)
Axon guidance (Homo sapiens)
Signaling by ROBO receptors (Homo sapiens)
Regulation of expression of SLITs and ROBOs (Homo sapiens)
LHX2 binds to ROBO1 gene locus (Homo sapiens)
LHX2 [nucleoplasm] (Homo sapiens)
LHX2 binds to ROBO2 gene locus (Homo sapiens)
LHX2 [nucleoplasm] (Homo sapiens)
Sensory Perception (Homo sapiens)
Olfactory Signaling Pathway (Homo sapiens)
Expression and translocation of olfactory receptors (Homo sapiens)
LHX2, LDB1, and EBF1 bind Olfactory Receptor gene and intergenic olfactory enhancers (Homo sapiens)
LHX2 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:P50458 LHX2
Gene Names
LHX2, LH2
Chain
chain:1-406
Reference Genes
BioGPS Gene:9355 LHX2
COSMIC (genes):LHX2 LHX2
CTD Gene:9355 LHX2
dbSNP Gene:9355 LHX2
ENSEMBL:ENSG00000106689 LHX2
HGNC:6594 LHX2
KEGG:hsa:9355 LHX2
Monarch:9355 LHX2
NCBI Gene:9355 LHX2
OMIM:603759 LHX2
UCSC:P50458 LHX2
Reference Transcript
RefSeq:NM_004789.3 LHX2
Other Identifiers
11736386_at
17088916
206140_PM_at
206140_at
211219_PM_s_at
211219_s_at
3188657
3188658
3188660
3188661
3188662
3188663
3188671
3188672
40528_at
8157751
9355
A_14_P126191
A_23_P32165
GE54835
GO:0000785
GO:0000977
GO:0000978
GO:0000981
GO:0001228
GO:0001843
GO:0001942
GO:0003677
GO:0003682
GO:0005515
GO:0005634
GO:0006325
GO:0006355
GO:0006357
GO:0007163
GO:0007399
GO:0007411
GO:0007420
GO:0007498
GO:0009953
GO:0021537
GO:0021772
GO:0021978
GO:0021987
GO:0022008
GO:0030154
GO:0030182
GO:0043226
GO:0043565
GO:0045199
GO:0045814
GO:0045893
GO:0045944
GO:0046872
GO:0048646
GO:0048675
GO:0048856
GO:0050768
GO:0060041
GO:0140110
GO:2000179
HMNXSV003018189
ILMN_1807016
PH_hs_0000210
TC09000633.hg
TC09002247.hg
U11701_at
g4758673_3p_at
g600494_3p_a_at
Participates
as an input of
LHX2, LDB1, and EBF1 bind Olfactory Receptor gene and intergenic olfactory enhancers (Homo sapiens)
LHX2 binds to ROBO1 gene locus (Homo sapiens)
LHX2 binds to ROBO2 gene locus (Homo sapiens)
as a component of
EBF1:LDB1:LHX2:Intergenic olfactory enhancer:Olfactory Receptor gene [nucleoplasm] (Homo sapiens)
LHX2:ROBO1 gene [nucleoplasm] (Homo sapiens)
LHX2:ROBO2 gene [nucleoplasm] (Homo sapiens)
as a member of
LHX2,(LHX9) [nucleoplasm] (Homo sapiens)
Cross References
RefSeq
NP_004780.3
OpenTargets
ENSG00000106689
ENSEMBL
ENST00000373615
,
ENSP00000362717
HPA
ENSG00000106689-LHX2
PRO
P50458
Pharos - Targets
P50458
Interactors (28)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q86U70 LDB1
1
LDB1 [nucleoplasm]
(R-HSA-8956515)
0.594
3
UniProt:Q9BWW4 SSBP3
0.569
3
UniProt:Q99650 OSMR
1
OSMR [plasma membrane]
(R-HSA-448654)
0.556
3
UniProt:A7KAX9 ARHGAP32
1
ARHGAP32 [cytosol]
(R-HSA-195134)
0.556
3
UniProt:Q9NSC5 HOMER3
1
HOMER3 [cytosol]
(R-HSA-6794236)
0.556
3
UniProt:Q12837 POU4F2
1
POU4F2 [nucleoplasm]
(R-HSA-6804414)
0.556
3
UniProt:P50053-2 KHK
0.556
3
UniProt:Q9UKI8 TLK1
0.556
3
UniProt:Q8NB15 ZN511
0.556
3
UniProt:Q8TBB1 LNX1
1
LNX1 [cytosol]
(R-HSA-8851641)
0.556
3
UniProt:Q17RB8 LONRF1
1
LONRF1 [cytosol]
(R-HSA-8850905)
0.556
3
UniProt:Q4VC44 FWCH1
0.556
3
UniProt:Q9UL33-2 TRAPPC2L
0.556
3
UniProt:Q96MM3 ZFP42
0.556
3
UniProt:Q9NUJ3 T11L1
0.556
3
UniProt:P31273 HOXC8
1
HOXC8 [nucleoplasm]
(R-HSA-3222311)
0.556
3
UniProt:Q3ZCW2 LEGL
0.556
3
UniProt:Q8NDZ0 BEND2
0.556
3
UniProt:P0CB47 UBFL1
0.556
3
UniProt:Q8N8B7-2 TCEANC
0.556
3
UniProt:Q49AR9 Q49AR9
0.556
3
UniProt:Q86U70-2 LDB1
0.556
3
UniProt:Q6PF18 MORN3
0.556
3
UniProt:Q9UBU8-2 MORF4L1
0.556
3
UniProt:Q9Y3C6 PPIL1
1
PPIL1 [nucleoplasm]
(R-HSA-8867892)
0.556
3
UniProt:Q9BWG4 SSBP4
0.483
2
UniProt:O00712 NFIB
1
NFIB [nucleoplasm]
(R-HSA-60136)
0.471
2
UniProt:Q12857 NFIA
1
NFIA [nucleoplasm]
(R-HSA-60134)
0.471
2
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