RAC2 translocates to the phagocytic vesicle membrane

Stable Identifier
Reaction [omitted]
Homo sapiens
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RAC2 is able to translocate from the plasma membrane compartment to the phagocytic vesicle membrane (Hoppe and Swanson 2004; Ueyama et al. 2005; Faure et al. 2013).

Literature References
PubMed ID Title Journal Year
23870057 The recruitment of p47(phox) and Rac2G12V at the phagosome is transient and phosphatidylserine dependent

Dupré-Crochet, S, Tschirhart, E, Delattre, M, Melchior, C, Prigent, M, Cuif, MH, Nüsse, O, Sulpice, JC, Faure, MC, Lavielle, M

Biol. Cell 2013
15169870 Cdc42, Rac1, and Rac2 display distinct patterns of activation during phagocytosis

Swanson, JA, Hoppe, AD

Mol Biol Cell 2004
16081809 Isoform-specific membrane targeting mechanism of Rac during Fc gamma R-mediated phagocytosis: positive charge-dependent and independent targeting mechanism of Rac to the phagosome

Takeya, R, Lennartz, MR, Saito, N, Sumimoto, H, Eto, M, Tatsuno, T, Kami, K, Shirai, Y, Kobayashi, T, Ueyama, T

J. Immunol. 2005
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