Reactome | KANK1 [nucleoplasm]

KANK1 [nucleoplasm]

Stable Identifier

R-HSA-9018640

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

KN motif and ankyrin repeat domain-containing protein 1, KANK1_HUMAN

Locations in the PathwayBrowser for interactor UniProt:Q9UQB8 BAIAP2

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External Reference Information

External Reference

UniProt:Q14678 KANK1

Gene Names

KANK1, ANKRD15, KANK, KIAA0172

Chain

chain:1-1352

Reference Genes

BioGPS Gene:23189 KANK1

COSMIC (genes):KANK1 KANK1

CTD Gene:23189 KANK1

dbSNP Gene:23189 KANK1

ENSEMBL:ENSG00000107104 KANK1

ENSEMBL_homo_sapiens_GENE:ENSG00000107104.21 KANK1

HGNC:19309 KANK1

KEGG Gene (Homo sapiens):23189 KANK1

Monarch:23189 KANK1

NCBI Gene:23189 KANK1

OMIM:607704 KANK1

UCSC:Q14678 KANK1

Reference Transcript

Other Identifiers

11731932_a_at

11758652_s_at

213005_PM_s_at

213005_s_at

23189

3159471

3159484

3159486

3159489

3159501

3159502

3159511

3159513

3159526

3159527

3159532

3159533

3159534

3159538

3159540

3159541

3159542

3159545

3159546

3159547

3159548

3159553

3159554

3159555

3159557

3159558

3159560

3159562

3159568

3159569

3159570

3159572

3159574

3159577

3159578

3159579

3159580

37225_at

3896520

8154012

A_19_P00315931

A_23_P500130

A_32_P64570

A_33_P3209866

D79994_at

GE57311

GO:0005515

GO:0005634

GO:0005737

GO:0005856

GO:0005886

GO:0007010

GO:0007155

GO:0007163

GO:0008013

GO:0008283

GO:0010977

GO:0016020

GO:0023052

GO:0030036

GO:0030154

GO:0030177

GO:0030336

GO:0030837

GO:0032587

GO:0035023

GO:0035024

GO:0042060

GO:0042995

GO:0043226

GO:0046627

GO:0048856

GO:0048870

GO:0065003

GO:0090263

GO:0090303

GO:0090521

GO:1900025

GO:1900028

GO:2000114

GO:2000393

HMNXSV003028884

HMNXSV003046363

Hs.77546.0.S1_3p_s_at

ILMN_1706031

ILMN_1773427

ILMN_1777727

PH_hs_0004472

TC09001785.hg

This entity regulates

Positively

Estrogen-responsive CXXC5 gene expresion (Homo sapiens)

Other forms of this molecule

p-12Y-KANK1(1-899)-PDGFRB(415-1106) fusion [plasma membrane]

KANK1(1-899)-PDGFRB(415-1106) fusion [plasma membrane]

Cross References

RefSeq

XP_016870016.1, XP_016870003.1, NP_694856.1, NP_001243806.1, XP_016870018.1, NP_055973.2, NP_001243805.1, XP_016870019.1, XP_016870004.1, XP_016870017.1

OpenTargets

ENSG00000107104

HPA

ENSG00000107104-KANK1

GeneCards

Q14678

Ensembl

ENST00000690372, ENSP00000371740, ENSP00000509433, ENSP00000371730, ENSP00000510058, ENSG00000107104, ENST00000687796, ENSP00000371734, ENST00000382303, ENST00000382293, ENST00000685947, ENST00000382297, ENST00000674102, ENST00000689779, ENSP00000508833, ENSP00000508451, ENSP00000501167

PRO

Q14678

Pharos - Targets

Q14678

Orphanet

17471

PDB

8IW0, 5YBU, 8AS9, 5YBJ

Interactors (7)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q7Z4S6 KIF21A	1	KIF21A [cytosol] (R-HSA-8849373)	0.748	5
UniProt:P63167 DYNLL1	6	DYNLL1 [ciliary tip] (R-HSA-5625335) DYNLL1 [cilium] (R-HSA-5624863) DYNLL1 [ficolin-1-rich granule membrane] (R-HSA-6801518) DYNLL1 [tertiary granule membrane] (R-HSA-6801482) DYNLL1 [plasma membrane] (R-HSA-54017) DYNLL1 [cytosol] (R-HSA-387105)	0.643	3
UniProt:Q9UQB8 BAIAP2	1	BAIAP2 [cytosol] (R-HSA-442574)	0.639	6
UniProt:Q9Y6D6 BIG1			0.632	8
UniProt:P27348 YWHAQ	1	YWHAQ [cytosol] (R-HSA-1445116)	0.589	2
UniProt:P48426 PIP4K2A	2	PIP4K2A [nucleoplasm] (R-HSA-6811484) PIP4K2A [cytosol] (R-HSA-1604641)	0.527	2
UniProt:Q96FJ2 DYNLL2	4	DYNLL2 [cytosol] (R-HSA-2029024) DYNLL2 [plasma membrane] (R-HSA-140527) DYNLL2 [cilium] (R-HSA-5624865) DYNLL2 [ciliary tip] (R-HSA-5625337)	0.527	2