MEF2C gene expression is inhibited by MECP2

Stable Identifier
R-HSA-9021949
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
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MEF2C gene expression is inhibited by MECP2
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Based on studies in mice, transcription of the MEF2C gene is directly inhibited by MECP2 (Chahrour et al. 2008). MEF2C encodes myocyte-specific enhancer factor 2C, a transcription factor involved in hippocampus-dependent learning and memory (Barbosa et al. 2008).
Participants
Input
Output
Participates
as an event of
This event is regulated
Negatively by
Regulator
MECP2:MEF2C gene [nucleoplasm] (Homo sapiens)
Active Unit
MECP2 [nucleoplasm]
Inferred From
Mef2c gene expression is inhibited by Mecp2 (Mus musculus)
Authored
Orlic-Milacic, M  (2017-10-02)
Reviewed
Krishnaraj, R  (2018-08-07)
Christodoulou, J  (2018-08-07)
Created
Orlic-Milacic, M  (2017-09-21)
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