HTT [nucleoplasm]

Stable Identifier
R-HSA-9023590
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Synonyms
Huntingtin
Locations in the PathwayBrowser for interactor UniProt:Q99961 SH3GL1
External Reference Information
External Reference
Gene Names
HTT, HD, IT15
Chain
chain:1-3142, chain:551-584
Reference Transcript
Other Identifiers
11719967_at
11719968_at
16964316
202389_PM_s_at
202389_s_at
202390_PM_s_at
202390_s_at
2715821
2715822
2715823
2715824
2715827
2715828
2715829
2715830
2715832
2715833
2715838
2715839
2715841
2715843
2715846
2715849
2715850
2715852
2715853
2715854
2715855
2715857
2715859
2715860
2715863
2715864
2715867
2715868
2715869
2715872
2715873
2715874
2715875
2715876
2715879
2715880
2715883
2715884
2715885
2715886
2715887
2715889
2715891
2715892
2715893
2715894
2715896
2715898
2715899
2715901
2715902
2715903
2715904
2715908
2715909
2715914
2715915
2715917
2715918
2715919
2715921
2715925
2715926
2715927
2715928
2715930
2715931
2715932
2715934
2715935
2715936
2715938
2715941
2715942
2715944
2715946
2715947
2715951
2715953
2715955
2715956
2715957
2715963
2715964
2715966
2715967
2715969
2715970
2715974
2715975
2715976
2715977
2715978
2715979
2715980
2715981
2715982
2715983
2715990
2715992
2715993
2715994
2715995
2715996
2715997
3064
37767_at
8093685
A_14_P121106
A_14_P129619
A_23_P212749
A_24_P180225
GE58274
GO:0000132
GO:0000278
GO:0002039
GO:0005515
GO:0005522
GO:0005634
GO:0005654
GO:0005737
GO:0005768
GO:0005769
GO:0005770
GO:0005773
GO:0005776
GO:0005783
GO:0005794
GO:0005814
GO:0005815
GO:0005829
GO:0005856
GO:0006890
GO:0006914
GO:0006915
GO:0007005
GO:0007010
GO:0007018
GO:0007030
GO:0007163
GO:0008092
GO:0012501
GO:0016192
GO:0016234
GO:0019900
GO:0023052
GO:0030424
GO:0030425
GO:0030659
GO:0031072
GO:0031410
GO:0031587
GO:0031648
GO:0032991
GO:0034452
GO:0036211
GO:0042297
GO:0042802
GO:0043065
GO:0043226
GO:0043666
GO:0044325
GO:0044782
GO:0045505
GO:0045724
GO:0047496
GO:0048471
GO:0048487
GO:0050877
GO:0055065
GO:0055085
GO:0099111
GO:0099523
GO:0099524
GO:1901526
GO:1904504
GO:1905289
GO:1905337
GO:2000479
GO:2001237
HMNXSV003027860
L12392_at
PH_hs_0025580
TC04000044.hg
g1709991_3p_a_at
g4755137_3p_a_at
Participates
Cross References
RefSeq
OpenTargets
ZINC - Substances
GeneCards
ZINC target
PRO
Pharos - Targets
Orphanet
ZINC - Predictions - Purchasable
Interactors (883)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P42858 HTT  1 0.889 11
 UniProt:Q96CV9 OPTN  6 0.824 15
 UniProt:Q8IUH5 ZDH17      0.809 30
 UniProt:O00291 HIP1  7 0.806 7
 UniProt:Q13501 SQSTM1  7 0.771 11
 UniProt:Q14204 DYNC1H1  3 0.766 8
 UniProt:Q14457 BECN1  4 0.766 15
 UniProt:O75400 PRPF40A  1 0.743 15
 UniProt:Q99963 SH3GL3  1 0.743 9
 UniProt:Q9BSL1 UBAC1  1 0.742 26
 UniProt:Q8N720 ZNF655  1 0.742 14
 UniProt:O14645 IDLC      0.742 15
 UniProt:Q96K21 ANCHR      0.742 21
 UniProt:P29692 EEF1D  1 0.742 6
 UniProt:Q9BVL2 NUP58      0.742 7
 UniProt:Q5VTR2 RNF20  2 0.742 24
 UniProt:P61086 UBE2K  2 0.742 24
 UniProt:Q99689 FEZ1      0.721 6
 UniProt:P54257-2 HAP1      0.715 8
 UniProt:P04637 TP53  20 0.709 19
 UniProt:Q8N2W9 PIAS4  2 0.703 6
 UniProt:Q14194 CRMP1  4 0.703 14
 UniProt:Q9Y3C7 MED31  1 0.703 9
 UniProt:Q96HT8 MR1L1      0.703 21
 UniProt:P68431 HIST1H3G  20 0.703 20
 UniProt:Q2NKX8 ERCC6L  1 0.703 20
 UniProt:P02792 FTL  4 0.703 20
 UniProt:Q9H4A5 GLP3L      0.703 20
 UniProt:P35080 PFN2  1 0.703 7
 UniProt:P12956 XRCC6  5 0.703 21
 UniProt:Q96NC0 ZMAT2  1 0.703 20
 UniProt:P54256 HAP1      0.681 3
 UniProt:O95243-2 MBD4      0.675 19
 UniProt:G3V1X1 G3V1X1      0.675 5
 UniProt:Q9UI08-2 EVL      0.675 20
 UniProt:P36578 RPL4  1 0.675 14
 UniProt:Q96ST3 SIN3A  2 0.675 4
 UniProt:O00746 NME4  1 0.675 20
 UniProt:P50221 MEOX1      0.675 19
 UniProt:Q9NP61 ARFGAP3  1 0.675 22
 UniProt:P23610 HAP40      0.675 4
 UniProt:P07910 HNRNPC  3 0.675 7
 UniProt:Q16891 IMMT  1 0.666 7
 UniProt:Q05516 ZBTB16  1 0.666 4
 UniProt:P49721 PSMB2  2 0.666 7
 UniProt:P14618 PKM  3 0.666 9
 UniProt:Q93034 CUL5  2 0.666 10
 UniProt:O75150 RNF40  1 0.666 12
 UniProt:O14818 PSMA7  2 0.666 13
 UniProt:Q02447 SP3  3 0.666 4
 UniProt:P50990 CCT8  5 0.666 4
 UniProt:P11142 HSPA8  10 0.666 14
 UniProt:Q9GZS3 SKIC8  2 0.666 22
 UniProt:Q13347 EIF3I  1 0.666 13
 UniProt:P25789 PSMA4  2 0.666 4
 UniProt:Q96EY1 DNJA3      0.666 5
 UniProt:P04406 GAPDH  1 0.666 7
 UniProt:P50502 ST13  1 0.666 13
 UniProt:Q13561 DCTN2  1 0.666 12
 UniProt:P46060 RANGAP1  3 0.666 10
 UniProt:P49327 FASN  3 0.666 13
 UniProt:P12074 COX6A1  1 0.666 4
 UniProt:Q9UNS2 COPS3  2 0.666 22
 UniProt:O00487 PSMD14  5 0.666 7
 UniProt:Q96M27 PRRC1      0.666 7
 UniProt:Q9P0J0 NDUFA13  8 0.666 4
 UniProt:P51665 PSMD7  5 0.666 10
 UniProt:P53618 COPB1  8 0.666 6
 UniProt:P51674 GPM6A      0.666 4
 UniProt:Q96M61 MAGBI      0.666 16
 UniProt:P20618 PSMB1  7 0.666 7
 UniProt:Q92890 UFD1L  2 0.666 7
 UniProt:Q9UK41 VPS28  1 0.666 16
 UniProt:P10606 COX5B  1 0.666 7
 UniProt:P40227 CCT6A  1 0.666 10
 UniProt:P78406 RAE1  1 0.666 4
 UniProt:Q9H444 CHMP4B  2 0.666 7
 UniProt:O75821 EIF3G  1 0.666 4
 UniProt:Q8N9I0 SYT2  3 0.666 10
 UniProt:O60573 EIF4E2  1 0.666 4
 UniProt:P08574 CYC1  3 0.666 7
 UniProt:P09669 COX6C  2 0.666 4
 UniProt:Q9H000 MKRN2      0.666 12
 UniProt:Q9NNZ3 DNJC4      0.666 12
 UniProt:Q9BVJ6 UTP14A  1 0.666 4
 UniProt:P60900 PSMA6  2 0.666 4
 UniProt:P63167 DYNLL1  6 0.666 10
 UniProt:P09471 GNAO1  1 0.666 7
 UniProt:O43813 LANC1      0.666 10
 UniProt:Q13283 G3BP1  1 0.666 16
 UniProt:O75409 HYPM      0.666 16
 UniProt:P09017 HOXC4  1 0.666 16
 UniProt:Q16795 NDUFA9  1 0.666 7
 UniProt:Q9Y605 MOFA1      0.666 19
 UniProt:P61962 DCAF7  2 0.666 10
 UniProt:Q9NX55 HYPK      0.666 4
 UniProt:P24534 EEF1B2  1 0.666 7
 UniProt:Q8TEX9 IPO4      0.666 7
 UniProt:O43248 HOXC11  1 0.666 7
 UniProt:P55036 PSMD4  1 0.666 5
 UniProt:P55072 VCP  8 0.666 10
 UniProt:Q9Y5Q9 GTF3C3  1 0.666 12
 UniProt:O00505 KPNA3  2 0.666 11
 UniProt:O43447 PPIH  2 0.666 10
 UniProt:O14901 KLF11      0.666 7
 UniProt:P37231 PPARG  2 0.666 16
 UniProt:P62873 GNB1  5 0.666 10
 UniProt:P62879 GNB2  4 0.666 10
 UniProt:P26373 RPL13  1 0.666 10
 UniProt:P51572 BCAP31  6 0.666 4
 UniProt:Q96N16 JKIP1      0.666 10
 UniProt:P31946 YWHAB  1 0.666 11
 UniProt:P41208 CETN2  3 0.666 13
 UniProt:O00165 HAX1      0.666 14
 UniProt:O75955 FLOT1  1 0.666 4
 UniProt:O43920 NDUFS5  1 0.666 7
 UniProt:O60437 PPL  2 0.666 8
 UniProt:P31689 DNAJA1  2 0.666 17
 UniProt:A4D1P6 WDR91  1 0.666 16
 UniProt:Q92569 PIK3R3  2 0.666 18
 UniProt:P63261 ACTG1  3 0.666 16
 UniProt:P62158 CALM      0.666 10
 UniProt:Q9UIV1 CNOT7  1 0.666 13
 UniProt:P09543 CN37      0.666 10
 UniProt:O75925 PIAS1  1 0.666 19
 UniProt:Q9H9A5 CNOT10  1 0.666 4
 UniProt:P45880 VDAC2  6 0.666 22
 UniProt:Q59EV6 Q59EV6      0.666 10
 UniProt:O96000 NDUFB10  1 0.666 13
 UniProt:Q9Y6H1 CHCHD2  2 0.666 10
 UniProt:P08247 SYP  1 0.666 13
 UniProt:Q9Y6M9 NDUFB9  1 0.666 10
 UniProt:Q96D09 GASP2      0.666 5
 UniProt:Q6PKC3 TXD11      0.666 7
 UniProt:P43243 MATR3      0.666 4
 UniProt:Q9Y3F4 STRAP  1 0.666 4
 UniProt:P13987 CD59  8 0.666 10
 UniProt:P15311 EZR  3 0.666 4
 UniProt:P06733 ENO1  1 0.666 13
 UniProt:Q13882 PTK6  5 0.666 4
 UniProt:P04156 PRNP  2 0.666 13
 UniProt:P08670 VIM  11 0.666 4
 UniProt:P61764 STXBP1  2 0.666 7
 UniProt:P62136 PPP1CA  1 0.666 10
 UniProt:P14136 GFAP  3 0.666 10
 UniProt:Q15149 PLEC  3 0.666 4
 UniProt:Q15119 PDK2  1 0.666 10
 UniProt:P35222 CTNNB1  20 0.666 14
 UniProt:P55345 ANM2      0.659 5
 UniProt:O75385 ULK1  7 0.612 8
 UniProt:Q9Y2X7 GIT1  2 0.602 10
 UniProt:Q9BY11 PACSIN1  1 0.592 3
 UniProt:Q8IZQ1 WDFY3      0.584 10
 UniProt:Q92793 CREBBP  4 0.573 2
 UniProt:Q16650 TBR1      0.556 12
 UniProt:Q8WY36-3 Q8WY363      0.556 6
 IntAct:EBI-25892128 CCSB      0.556 3
 UniProt:P49720 PSMB3  2 0.556 3
 UniProt:Q9BQJ4 TMM47      0.556 3
 UniProt:Q9C0F3 ZNF436  1 0.556 15
 UniProt:Q9UNL4 ING4  1 0.556 3
 UniProt:Q3ZCN5 OTOGL  1 0.556 3
 UniProt:Q5T7P3 LCE1B  1 0.556 15
 UniProt:Q96D59 RN183      0.556 3
 UniProt:Q86TN1 Q86TN1      0.556 9
 UniProt:P48643 CCT5  1 0.556 3
 UniProt:Q8WWW0-2 RASSF5      0.556 3
 UniProt:Q99608 NDN  1 0.556 6
 UniProt:Q9H0V9 LMAN2L  3 0.556 3
 UniProt:Q14693 LPIN1  3 0.556 12
 UniProt:Q9H7C9 AAMDC      0.556 3
 UniProt:Q9NPC3 CIP1      0.556 6
 IntAct:EBI-25894571 CCSB      0.556 3
 UniProt:P35548 MSX2  1 0.556 12
 UniProt:Q6P1W5 CA094      0.556 3
 UniProt:Q8TC29 ENKUR      0.556 6
 UniProt:Q9BTA9-5 WAC      0.556 3
 UniProt:Q96AM0 Q96AM0      0.556 3
 UniProt:Q13113 PDZ1I      0.556 21
 UniProt:Q9H171 ZBP1  1 0.556 6
 UniProt:Q12765-2 SCRN1      0.556 3
 UniProt:Q15776 ZKSCAN8  1 0.556 9
 UniProt:Q7L8T7 Q7L8T7      0.556 6
 IntAct:EBI-25866297 CCSB      0.556 15
 UniProt:Q9GZL8 BPEC1      0.556 15
 UniProt:Q9NPI8 FANCF  2 0.556 3
 UniProt:P51608 MECP2      0.556 18
 UniProt:Q9UHD9 UBQLN2  1 0.556 12
 UniProt:Q99871 HAUS7  1 0.556 18
 UniProt:Q9GZR2 REXO4      0.556 3
 UniProt:Q9BUW7 BBLN      0.556 6
 UniProt:Q53G59 KLHL12  1 0.556 3
 IntAct:EBI-25850770 CCSB      0.556 6
 UniProt:Q00266 MAT1A  4 0.556 3
 UniProt:Q9Y2M5 KLHL20  1 0.556 9
 UniProt:P26885 FKBP2      0.556 6
 UniProt:A2RU56 A2RU56      0.556 9
 UniProt:Q5VWN6 TASO2      0.556 12
 UniProt:Q9UHD4 CIDEB      0.556 3
 UniProt:P00492 HPRT1  4 0.556 15
 UniProt:Q13573 SNW1  1 0.556 12
 UniProt:Q02218 OGDH  1 0.556 3
 UniProt:P48443 RXRG  1 0.556 18
 UniProt:P22033 MMUT  10 0.556 12
 UniProt:P48444 ARCN1  4 0.556 3
 UniProt:P25786 PSMA1  2 0.556 3
 UniProt:Q96FT7-4 ASIC4      0.556 3
 UniProt:P62979 RPS27A  20 0.556 6
 UniProt:Q9UPU5 USP24  1 0.556 21
 UniProt:Q13588 GRAP  1 0.556 12
 UniProt:Q16853 AOC3  1 0.556 3
 UniProt:Q93079 H2BC9  9 0.556 18
 UniProt:Q96JM7-2 L3MBTL3      0.556 3
 UniProt:O75351 VPS4B  1 0.556 3
 UniProt:Q99614 TTC1      0.556 9
 UniProt:O75356 ENTPD5  1 0.556 3
 UniProt:Q9NY87 SPNXC      0.556 3
 UniProt:P23396 RPS3  2 0.556 3
 UniProt:Q96EY4 TMA16      0.556 3
 UniProt:P40939 HADHA  1 0.556 3
 UniProt:Q6ZMI0-5 PPP1R21      0.556 9
 UniProt:Q6UW68 TM205      0.556 3
 UniProt:O14662-5 STX16      0.556 15
 UniProt:P50749 RASF2      0.556 3
 UniProt:Q7Z7K6 CENPV      0.556 15
 UniProt:Q96EZ8 MCRS1  1 0.556 3
 UniProt:Q8IWZ3-3 ANKHD1      0.556 3
 UniProt:Q8TC84 FANK1      0.556 3
 UniProt:Q2QGD7 ZXDC      0.556 3
 UniProt:Q13562 NEUROD1  1 0.556 6
 UniProt:Q9BT81 SOX7  1 0.556 15
 UniProt:Q9BSW2 CRACR2A  2 0.556 9
 UniProt:Q9UPQ4-2 Q9UPQ42      0.556 9
 UniProt:P50570-2 DNM2      0.556 6
 UniProt:Q3SY56 SP6      0.556 3
 UniProt:B7Z3E8 B7Z3E8      0.556 6
 UniProt:P29466-3 CASP1      0.556 3
 UniProt:Q8N779 Q8N779      0.556 15
 UniProt:Q96FA3 PELI1  2 0.556 3
 UniProt:Q9BZE4 GTPB4      0.556 3
 UniProt:O60749 SNX2  2 0.556 6
 UniProt:O00203 AP3B1  4 0.556 6
 IntAct:EBI-25872354 ORF      0.556 12
 UniProt:Q3SY69 ALDH1L2  1 0.556 3
 UniProt:Q99683 MAP3K5  1 0.556 6
 UniProt:Q5T7P8-2 SYT6      0.556 3
 UniProt:Q7Z3I7 ZN572      0.556 9
 UniProt:P52744 ZNF138  1 0.556 9
 UniProt:Q9UHI6 DDX20  2 0.556 6
 UniProt:P02489 CRYAA      0.556 3
 UniProt:Q9NPJ8-3 NXT2      0.556 15
 UniProt:P21980-2 P219802      0.556 6
 UniProt:P54920 NAPA  1 0.556 3
 UniProt:Q9HBE1-4 PATZ1      0.556 3
 UniProt:O14602 IF1AY      0.556 6
 UniProt:Q13303 KCNAB2  3 0.556 3
 UniProt:Q32MN6 Q32MN6      0.556 9
 UniProt:Q6PCB6 ABHD17C  1 0.556 21
 UniProt:Q9UHX1-2 PUF60      0.556 6
 IntAct:EBI-25911596 CCSB      0.556 3
 UniProt:P0DMV8 HSPA1A  4 0.556 9
 UniProt:Q6ZTN6-2 ANKRD13D      0.556 9
 UniProt:Q96HB5 CC120      0.556 3
 UniProt:P17987 TCP1  1 0.556 3
 UniProt:Q96HC4 PDLIM5  1 0.556 9
 UniProt:Q86YB0 Q86YB0      0.556 3
 UniProt:Q13702-2 Q137022      0.556 18
 UniProt:Q15047-2 SETDB1      0.556 15
 IntAct:EBI-25836274 CCSB      0.556 12
 UniProt:Q92797-2 Q927972      0.556 9
 UniProt:Q9UHX1-6 PUF60      0.556 9
 UniProt:Q8NCS7 SLC44A5  1 0.556 3
 UniProt:Q9NS69 TOMM22  1 0.556 6
 UniProt:Q99471 PFDN5  1 0.556 3
 UniProt:Q16799-3 RTN1      0.556 9
 UniProt:Q92609 TBCD5      0.556 3
 UniProt:P0CI25 TRI49      0.556 9
 UniProt:P48730-2 CSNK1D      0.556 15
 UniProt:P25398 RPS12  2 0.556 3
 UniProt:P05783 KRT18  1 0.556 6
 UniProt:Q71RG4-4 Q71RG44      0.556 6
 UniProt:Q6NXT2 H3C      0.556 15
 UniProt:Q6NW12 Q6NW12      0.556 9
 UniProt:Q9BXP5-4 SRRT      0.556 3
 UniProt:Q9BXP5-3 SRRT      0.556 6
 UniProt:P20936 RASA1  1 0.556 3
 UniProt:Q9ULV1 FZD4  3 0.556 9
 UniProt:Q9BVA6 FICD      0.556 3
 UniProt:Q16181-2 SEPTIN7      0.556 9
 UniProt:P48047 ATP5PO  1 0.556 6
 UniProt:P54725 RAD23A  1 0.556 3
 UniProt:Q9NR11-2 ZNF302      0.556 3
 UniProt:Q92615 LAR4B      0.556 3
 UniProt:P61009 SPCS3  1 0.556 6
 UniProt:Q12891 HYAL2  1 0.556 9
 UniProt:Q15528-2 MED22      0.556 12
 UniProt:P19838-2 NFKB1      0.556 3
 UniProt:O00471 EXOC5  2 0.556 3
 UniProt:Q99459 CDC5L  1 0.556 3
 UniProt:O76041 NEBL      0.556 18
 UniProt:Q53R41 FAKD1      0.556 9
 UniProt:P56545-3 CTBP2      0.556 3
 UniProt:Q08379 GOLGA2  3 0.556 3
 UniProt:P52756 RBM5  1 0.556 6
 UniProt:Q9Y4W6 AFG3L2  1 0.556 3
 UniProt:P51660 Hsd17b4  5 0.556 15
 UniProt:Q14005-2 Q140052      0.556 15
 UniProt:P62316 SNRPD2  2 0.556 3
 UniProt:Q9UNX3 RPL26L1  1 0.556 3
 UniProt:Q7Z602 GP141      0.556 3
 UniProt:P20719 HXA5      0.556 9
 UniProt:Q9BR01-2 Q9BR012      0.556 15
 IntAct:EBI-25851697 CCSB      0.556 6
 UniProt:Q8NCR9 CLRN3      0.556 9
 UniProt:Q15904 ATP6AP1  2 0.556 3
 UniProt:P28676 GCA  2 0.556 3
 UniProt:Q9H816 DCLRE1B  1 0.556 9
 UniProt:Q9H3H5 DPAGT1  8 0.556 3
 UniProt:P16220 CREB1      0.556 3
 UniProt:Q8N988-2 ZNF557      0.556 12
 UniProt:Q12874 SF3A3  1 0.556 3
 UniProt:Q9Y4X4 KLF12      0.556 3
 UniProt:Q9Y2T2 AP3M1  1 0.556 3
 UniProt:Q9H9Z2 LIN28A  1 0.556 18
 UniProt:Q8TCE9 PPL13      0.556 3
 IntAct:EBI-25853680 CCSB      0.556 3
 UniProt:P04141 CSF2 gene  1 0.556 15
 UniProt:Q7Z417 NUFP2      0.556 6
 UniProt:Q9NWB7 IFT57  2 0.556 3
 UniProt:Q9UQB8-3 BAIAP2      0.556 18
 UniProt:O15130-2 O151302      0.556 18
 UniProt:Q13939 CALI      0.556 3
 UniProt:Q9UQB8-6 BAIAP2      0.556 18
 UniProt:Q07020 RPL18  1 0.556 12
 UniProt:Q9UI12 ATP6V1H  2 0.556 3
 UniProt:P62256 UBE2H  2 0.556 3
 UniProt:P39019 RPS19  2 0.556 3
 UniProt:O95455 TGDS      0.556 3
 UniProt:Q08117 TLE5  1 0.556 3
 UniProt:Q8IZU1 FAM9A      0.556 18
 UniProt:Q9UBE8 NLK  3 0.556 3
 UniProt:O95073-2 FSBP      0.556 3
 UniProt:O15535 ZSC9      0.556 9
 UniProt:Q13635-3 PTCH1      0.556 3
 UniProt:Q9UJU6 DBNL  7 0.556 3
 UniProt:P62244 RPS15A  2 0.556 3
 UniProt:Q9ULW3 ABT1      0.556 9
 UniProt:Q8N594 MPND      0.556 3
 UniProt:Q99497 PARK7  7 0.556 6
 UniProt:O95447 LCA5L      0.556 18
 UniProt:Q96M34 TEX55      0.556 3
 UniProt:Q8NEZ2 VPS37A  1 0.556 6
 UniProt:P31749 AKT1