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PEX26 [peroxisomal membrane]
Stable Identifier
R-HSA-9033092
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
peroxisomal membrane
Synonyms
Peroxisome assembly protein 26, PEX26_HUMAN
Locations in the PathwayBrowser
Expand all
Protein localization (Homo sapiens)
Class I peroxisomal membrane protein import (Homo sapiens)
PEX3:PEX19:class I PMP dissociates (Homo sapiens)
Class I Peroxisomal Membrane Proteins [peroxisomal membrane] (Homo sapiens)
PEX26 [peroxisomal membrane] (Homo sapiens)
Peroxisomal protein import (Homo sapiens)
PEX1:PEX6:PEX26:ZFAND6 dissociates Ub:PEX5L and PEX7 from PEX14:PEX13:PEX2:PEX10:PEX12 and translocates PEX5L and PEX7 from the peroxisomal membrane to the cytosol (Homo sapiens)
PEX1:PEX6:PEX26 [peroxisomal membrane] (Homo sapiens)
PEX26 [peroxisomal membrane] (Homo sapiens)
PEX2:PEX10:PEX12:Ub:PEX5L:PEX7:PEX13:PEX14:PEX1:PEX6:PEX26:ZFAND6 [peroxisomal membrane] (Homo sapiens)
PEX1:PEX6:PEX26 [peroxisomal membrane] (Homo sapiens)
PEX26 [peroxisomal membrane] (Homo sapiens)
PEX1:PEX6:PEX26:ZFAND6:Ub:PEX5S,L:PEX14:PEX13:PEX2:PEX10:PEX12 dissociates yielding cytosolic Ub:PEX5S,L and membrane PEX14:PEX13:PEX2:PEX10:PEX12 (Homo sapiens)
PEX1:PEX6:PEX26 [peroxisomal membrane] (Homo sapiens)
PEX26 [peroxisomal membrane] (Homo sapiens)
PEX2:PEX10:PEX12:Ub:PEX5S,L:PEX1:PEX6:PEX26:ZFAND6 [peroxisomal membrane] (Homo sapiens)
PEX1:PEX6:PEX26 [peroxisomal membrane] (Homo sapiens)
PEX26 [peroxisomal membrane] (Homo sapiens)
PEX2:PEX10:PEX12:Ub:PEX5L:PEX7:PEX13:PEX14 binds PEX1:PEX6:PEX26 and ZFAND6 (Homo sapiens)
PEX1:PEX6:PEX26 [peroxisomal membrane] (Homo sapiens)
PEX26 [peroxisomal membrane] (Homo sapiens)
PEX2:PEX10:PEX12:Ub:PEX5L:PEX7:PEX13:PEX14:PEX1:PEX6:PEX26:ZFAND6 [peroxisomal membrane] (Homo sapiens)
PEX1:PEX6:PEX26 [peroxisomal membrane] (Homo sapiens)
PEX26 [peroxisomal membrane] (Homo sapiens)
PEX2:PEX10:PEX12:Ub:PEX5S,L:PEX13:PEX14 binds PEX1:PEX6:PEX26 and ZFAND6 (Homo sapiens)
PEX1:PEX6:PEX26 [peroxisomal membrane] (Homo sapiens)
PEX26 [peroxisomal membrane] (Homo sapiens)
PEX2:PEX10:PEX12:Ub:PEX5S,L:PEX1:PEX6:PEX26:ZFAND6 [peroxisomal membrane] (Homo sapiens)
PEX1:PEX6:PEX26 [peroxisomal membrane] (Homo sapiens)
PEX26 [peroxisomal membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q7Z412 PEX26
Gene Names
PEX26
Chain
chain:1-305
Reference Genes
BioGPS Gene:55670 PEX26
COSMIC (genes):PEX26 PEX26
CTD Gene:55670 PEX26
dbSNP Gene:55670 PEX26
ENSEMBL:ENSG00000215193 PEX26
HGNC:22965 PEX26
Monarch:55670 PEX26
NCBI Gene:55670 PEX26
OMIM:608666 PEX26
UCSC:Q7Z412 PEX26
Reference Transcript
RefSeq:NM_001199319.1 PEX26
RefSeq:NM_001127649.2 PEX26
RefSeq:NM_017929.5 PEX26
Other Identifiers
11730953_a_at
11730954_a_at
11736832_a_at
16926922
16926932
219180_PM_s_at
219180_s_at
235098_PM_at
235098_at
240123_PM_at
240123_at
3936446
3936447
3936448
3936449
3936450
3936451
3936452
3936455
3936456
3936457
3936459
3936460
3936462
3936463
3936464
3936465
3936466
3936468
3936469
3936470
3936471
3936472
3936473
3936474
3936475
3936476
3936477
3936478
3936479
3936500
3936502
3936503
3936505
3936507
3936509
3936511
3936513
3936514
3936516
3936517
3936518
3936519
3936520
3936521
3936532
3936534
3936536
3936538
3936540
3936541
3936543
3936545
45708_i_at
45709_r_at
50052_i_at
50055_r_at
55670
60592_at
60671_at
62200_at
76507_at
8071136
86037_at
A_14_P108335
A_14_P132927
A_24_P142973
A_33_P3262452
A_33_P3412519
GE494100
GE55595
GE838500
GE868789
GO:0005515
GO:0005777
GO:0005778
GO:0005829
GO:0006886
GO:0007031
GO:0015031
GO:0016020
GO:0016558
GO:0022615
GO:0043226
GO:0043495
GO:0044877
GO:0045046
GO:0051117
GO:0055085
GO:0060090
HMNXSV003006694
Hs.127953.0.S1_3p_at
Hs.177169.0.A1_3p_at
Hs.5420.0.S1_3p_a_at
ILMN_1770643
ILMN_2130409
PH_hs_0013638
PH_hs_0026013
TC22000947.hg
TC22001451.hg
Participates
as a member of
Class I Peroxisomal Membrane Proteins [peroxisomal membrane] (Homo sapiens)
as a component of
PEX1:PEX6:PEX26 [peroxisomal membrane] (Homo sapiens)
Other forms of this molecule
PEX26 [cytosol]
Inferred To
Ghost homologue of PEX26 [peroxisomal membrane]
(Caenorhabditis elegans)
Ghost homologue of PEX26 [peroxisomal membrane]
(Canis familiaris)
Ghost homologue of PEX26 [peroxisomal membrane]
(Dictyostelium discoideum)
Ghost homologue of PEX26 [peroxisomal membrane]
(Drosophila melanogaster)
Ghost homologue of PEX26 [peroxisomal membrane]
(Saccharomyces cerevisiae)
Ghost homologue of PEX26 [peroxisomal membrane]
(Schizosaccharomyces pombe)
pex26 [peroxisomal membrane]
(Danio rerio)
Pex26 [peroxisomal membrane]
(Mus musculus)
PEX26 [peroxisomal membrane]
(Bos taurus)
PEX26 [peroxisomal membrane]
(Gallus gallus)
PEX26 [peroxisomal membrane]
(Rattus norvegicus)
PEX26 [peroxisomal membrane]
(Sus scrofa)
Cross References
ENSEMBL
ENSP00000382648
,
ENST00000329627
,
ENST00000399744
,
ENST00000428061
,
ENSP00000331106
,
ENSP00000412441
OpenTargets
ENSG00000215193
HPA
ENSG00000215193-PEX26
PRO
Q7Z412
Pharos - Targets
Q7Z412
Orphanet
PEX26
Interactors (9)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P40855 PEX19
1
PEX19 [cytosol]
(R-HSA-3009036)
0.683
9
UniProt:O15392 BIRC5
3
BIRC5 [cytosol]
(R-HSA-50851)
BIRC5 [nucleoplasm]
(R-HSA-4655344)
ub-BIRC5 [cytosol]
(R-HSA-8955933)
0.556
3
UniProt:Q96NC0 ZMAT2
1
ZMAT2 [nucleoplasm]
(R-HSA-9770248)
0.556
3
UniProt:Q9UER7 DAXX
13
DAXX [nucleoplasm]
(R-HSA-3222068)
DAXX A36Qfs*108 [nucleoplasm]
(R-HSA-9673105)
DAXX K56* [nucleoplasm]
(R-HSA-9673089)
DAXX A103Sfs*40 [nucleoplasm]
(R-HSA-9673121)
DAXX C106* [nucleoplasm]
(R-HSA-9673079)
DAXX E72Nfs*72 [nucleoplasm]
(R-HSA-9673110)
DAXX E104* [nucleoplasm]
(R-HSA-9673078)
DAXX H26Tfs*118 [nucleoplasm]
(R-HSA-9673114)
DAXX S138* [nucleoplasm]
(R-HSA-9673081)
DAXX C74* [nucleoplasm]
(R-HSA-9673096)
DAXX R48Vfs*93 [nucleoplasm]
(R-HSA-9673103)
DAXX L98Vfs*13 [nucleoplasm]
(R-HSA-9673102)
monoSUMO1-K630,K631-DAXX [nucleoplasm]
(R-HSA-4086086)
0.556
3
UniProt:P04637 TP53
20
Unfolded TP53 [cytosol]
(R-HSA-6813797)
TP53 [cytosol]
(R-HSA-8869337)
PolyUb-TP53 [nucleoplasm]
(R-HSA-6782509)
polySUMO2,3-K386-TP53 [nucleoplasm]
(R-HSA-2997661)
TP53 F341C [nucleoplasm]
(R-HSA-9726318)
TP53 G334V [nucleoplasm]
(R-HSA-9726126)
TP53 L330H [nucleoplasm]
(R-HSA-9726124)
TP53 A347T [nucleoplasm]
(R-HSA-9726339)
TP53 R337C [nucleoplasm]
(R-HSA-9726118)
TP53 L344P [nucleoplasm]
(R-HSA-9726075)
TP53 L344R [nucleoplasm]
(R-HSA-9726073)
TP53 R337H [nucleoplasm]
(R-HSA-9726169)
TP53 R337P [nucleoplasm]
(R-HSA-9726168)
TP53 L330P [nucleoplasm]
(R-HSA-9726136)
TP53 L348S [nucleoplasm]
(R-HSA-9726366)
TP53 R337L [nucleoplasm]
(R-HSA-9726163)
TP53 K351E [nucleoplasm]
(R-HSA-9726258)
TP53 F338I [nucleoplasm]
(R-HSA-9726358)
TP53 R342P [nucleoplasm]
(R-HSA-9726101)
TP53 L330R [nucleoplasm]
(R-HSA-9726133)
0.556
3
UniProt:Q969S8 HDAC10
1
HDAC10 [nucleoplasm]
(R-HSA-351579)
0.556
3
UniProt:Q96LC9 BMF
3
BMF [plasma membrane]
(R-HSA-140209)
p-BMF(1-89) [cytosol]
(R-HSA-140529)
p-BMF [mitochondrial outer membrane]
(R-HSA-3145026)
0.556
3
UniProt:A0AVK6 E2F8
1
E2F8 [nucleoplasm]
(R-HSA-8952990)
0.556
3
UniProt:Q9UMX1 SUFU
3
SUFU [ciliary base]
(R-HSA-5610424)
SUFU [cytosol]
(R-HSA-445455)
SUFU [ciliary tip]
(R-HSA-5610426)
0.508
2
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