TYSND1 cleaves AGPS

Stable Identifier
R-HSA-9033506
Type
Reaction [transition]
Species
Homo sapiens
Compartment
peroxisomal matrix
ReviewStatus
5/5
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TYSND1 cleaves AGPS
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The trypsin-like serine-type endopeptidase TYSND1 cleaves AGPS between amino acid residues 58 and 59, yielding AGPS(1-58) and AGPS(59-658) (inferred from mouse homologs). In mice, knockout of TYSND1 causes reduced localization of AGPS to the peroxisome.
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Catalyst Activity

serine-type endopeptidase activity of TYSND1 [peroxisomal matrix]

Physical Entity
TYSND1 [peroxisomal matrix] (Homo sapiens)
Activity
serine-type endopeptidase activity (GO:0004252)
Inferred From
Tysnd1 cleaves Agps (Mus musculus)
Authored
May, B  (2017-12-22)
Reviewed
Van Veldhoven, PP  (2018-02-13)
Fransen, M  (2018-02-13)
Azevedo, JE  (2018-03-12)
Created
May, B  (2017-12-22)
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