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About
What is Reactome ?
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IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane]
Stable Identifier
R-HSA-912308
Type
Complex
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Interleukin-3 receptor
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Cytokine Signaling in Immune system (Homo sapiens)
Signaling by Interleukins (Homo sapiens)
Interleukin-2 family signaling (Homo sapiens)
Interleukin receptor SHC signaling (Homo sapiens)
Gab2 binds the p85 subunit of Class 1A PI3 kinases (Homo sapiens)
Interleukin receptor complexes with activated Shc:GRB2:p-GAB2 [plasma membrane] (Homo sapiens)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, phosphorylated Bc [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane] (Homo sapiens)
IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane] (Homo sapiens)
Interleukin receptor complexes with activated Shc:GRB2:p-GAB2:p85-containing Class 1 PI3Ks [plasma membrane] (Homo sapiens)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:p(Y)-GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, phosphorylated Bc [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane] (Homo sapiens)
IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane] (Homo sapiens)
Phosphorylated SHC recruits GRB2:SOS1 (Homo sapiens)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Homo sapiens)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane] (Homo sapiens)
IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane] (Homo sapiens)
Interleukin receptor complexes with activated SHC1:GRB2:SOS1 [plasma membrane] (Homo sapiens)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Homo sapiens)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane] (Homo sapiens)
IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane] (Homo sapiens)
Phosphorylated SHC1 recruits GRB2:GAB2 (Homo sapiens)
Interleukin receptor compexes with activated Shc:GRB2:GAB2 [plasma membrane] (Homo sapiens)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, phosphorylated Bc [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane] (Homo sapiens)
IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane] (Homo sapiens)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Homo sapiens)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane] (Homo sapiens)
IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane] (Homo sapiens)
Phosphorylated SHC1 recruits SHIP (Homo sapiens)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Homo sapiens)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane] (Homo sapiens)
IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane] (Homo sapiens)
Interleukin receptor complexes with activated SHC1:SHIP1,2 [plasma membrane] (Homo sapiens)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Homo sapiens)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane] (Homo sapiens)
IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane] (Homo sapiens)
SHC1 mediates cytokine-induced phosphorylation of GAB2 (Homo sapiens)
Interleukin receptor compexes with activated Shc:GRB2:GAB2 [plasma membrane] (Homo sapiens)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, phosphorylated Bc [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane] (Homo sapiens)
IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane] (Homo sapiens)
Interleukin receptor complexes with activated Shc:GRB2:p-GAB2 [plasma membrane] (Homo sapiens)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, phosphorylated Bc [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane] (Homo sapiens)
IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane] (Homo sapiens)
The SHC1:SHIP1 complex is stabilized by GRB2 (Homo sapiens)
Interleukin receptor complexes with activated SHC1:SHIP1 [plasma membrane] (Homo sapiens)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Homo sapiens)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane] (Homo sapiens)
IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane] (Homo sapiens)
Interleukin receptor complexes with activated SHC1:SHIP:GRB2 [plasma membrane] (Homo sapiens)
Interleukin receptor complexes with activated SHC1:SHIP1 [plasma membrane] (Homo sapiens)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Homo sapiens)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane] (Homo sapiens)
IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane] (Homo sapiens)
Interleukin-3, Interleukin-5 and GM-CSF signaling (Homo sapiens)
Interleukin receptor SHC signaling (Homo sapiens)
Gab2 binds the p85 subunit of Class 1A PI3 kinases (Homo sapiens)
Interleukin receptor complexes with activated Shc:GRB2:p-GAB2 [plasma membrane] (Homo sapiens)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, phosphorylated Bc [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane] (Homo sapiens)
IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane] (Homo sapiens)
Interleukin receptor complexes with activated Shc:GRB2:p-GAB2:p85-containing Class 1 PI3Ks [plasma membrane] (Homo sapiens)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:p(Y)-GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, phosphorylated Bc [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane] (Homo sapiens)
IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane] (Homo sapiens)
Phosphorylated SHC recruits GRB2:SOS1 (Homo sapiens)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Homo sapiens)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane] (Homo sapiens)
IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane] (Homo sapiens)
Interleukin receptor complexes with activated SHC1:GRB2:SOS1 [plasma membrane] (Homo sapiens)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Homo sapiens)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane] (Homo sapiens)
IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane] (Homo sapiens)
Phosphorylated SHC1 recruits GRB2:GAB2 (Homo sapiens)
Interleukin receptor compexes with activated Shc:GRB2:GAB2 [plasma membrane] (Homo sapiens)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, phosphorylated Bc [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane] (Homo sapiens)
IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane] (Homo sapiens)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Homo sapiens)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane] (Homo sapiens)
IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane] (Homo sapiens)
Phosphorylated SHC1 recruits SHIP (Homo sapiens)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Homo sapiens)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane] (Homo sapiens)
IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane] (Homo sapiens)
Interleukin receptor complexes with activated SHC1:SHIP1,2 [plasma membrane] (Homo sapiens)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Homo sapiens)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane] (Homo sapiens)
IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane] (Homo sapiens)
SHC1 mediates cytokine-induced phosphorylation of GAB2 (Homo sapiens)
Interleukin receptor compexes with activated Shc:GRB2:GAB2 [plasma membrane] (Homo sapiens)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, phosphorylated Bc [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane] (Homo sapiens)
IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane] (Homo sapiens)
Interleukin receptor complexes with activated Shc:GRB2:p-GAB2 [plasma membrane] (Homo sapiens)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, phosphorylated Bc [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane] (Homo sapiens)
IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane] (Homo sapiens)
The SHC1:SHIP1 complex is stabilized by GRB2 (Homo sapiens)
Interleukin receptor complexes with activated SHC1:SHIP1 [plasma membrane] (Homo sapiens)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Homo sapiens)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane] (Homo sapiens)
IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane] (Homo sapiens)
Interleukin receptor complexes with activated SHC1:SHIP:GRB2 [plasma membrane] (Homo sapiens)
Interleukin receptor complexes with activated SHC1:SHIP1 [plasma membrane] (Homo sapiens)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Homo sapiens)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane] (Homo sapiens)
IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane] (Homo sapiens)
Recruitment of SHC1 is mediated by Y593 of the common beta chain (Homo sapiens)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)-Bc [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane] (Homo sapiens)
IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane] (Homo sapiens)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)-Bc:SHC1 [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, inactive JAK2, phosphorylated Bc:SHC1 [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane] (Homo sapiens)
IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane] (Homo sapiens)
SHC1 bound to the common beta chain becomes tyrosine phosphorylated (Homo sapiens)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)-Bc:SHC1 [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, inactive JAK2, phosphorylated Bc:SHC1 [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane] (Homo sapiens)
IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane] (Homo sapiens)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane] (Homo sapiens)
IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane] (Homo sapiens)
SHP1 and SHP2 bind the common beta chain (Homo sapiens)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)-Bc [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane] (Homo sapiens)
IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane] (Homo sapiens)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2,p(Y593,628)-Bc:SHP1, SHP2 [plasma membrane] (Homo sapiens)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)-Bc [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane] (Homo sapiens)
IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane] (Homo sapiens)
SHP1 and SHP2 dephosphorylate Y628 of IL3RB (Homo sapiens)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2,p(Y593,628)-Bc:SHP1, SHP2 [plasma membrane] (Homo sapiens)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)-Bc [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane] (Homo sapiens)
IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane] (Homo sapiens)
Tyrosine kinases phosphorylate the receptor (Homo sapiens)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)-Bc [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane] (Homo sapiens)
IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane] (Homo sapiens)
Signal Transduction (Homo sapiens)
MAPK family signaling cascades (Homo sapiens)
MAPK1/MAPK3 signaling (Homo sapiens)
RAF/MAP kinase cascade (Homo sapiens)
RAS GEFs promote RAS nucleotide exchange (Homo sapiens)
RAS GEFs [plasma membrane] (Homo sapiens)
Interleukin receptor complexes with activated SHC1:GRB2:SOS1 [plasma membrane] (Homo sapiens)
Interleukin receptor complexes with activated SHC1 [plasma membrane] (Homo sapiens)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1 [plasma membrane] (Homo sapiens)
IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane] (Homo sapiens)
IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane] (Homo sapiens)
Participants
components
IL3:IL3RA [plasma membrane]
(Homo sapiens)
pY593,Y628-IL3RB:JAK2 [plasma membrane]
(Homo sapiens)
Participates
as a component of
IL3:IL3R active complex, JAK2:p-Y593,Y629-IL3RB [plasma membrane] (Homo sapiens)
Inferred To
IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane]
(Bos taurus)
IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane]
(Canis familiaris)
IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane]
(Gallus gallus)
IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane]
(Mus musculus)
IL3:IL3RA:p-Y593,Y628-IL3RB:JAK2 [plasma membrane]
(Rattus norvegicus)
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