Reactome | TEX12 [nucleoplasm]

TEX12 [nucleoplasm]

Stable Identifier

R-HSA-912441

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Testis-expressed sequence 12 protein, TEX12_HUMAN

Locations in the PathwayBrowser for interactor UniProt:Q7Z3B4 NUP54

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External Reference Information

External Reference

UniProt:Q9BXU0 TEX12

Gene Names

TEX12

Chain

chain:1-123

Reference Genes

BioGPS Gene:56158 TEX12

COSMIC (genes):TEX12 TEX12

CTD Gene:56158 TEX12

dbSNP Gene:56158 TEX12

ENSEMBL:ENSG00000150783 TEX12

HGNC:11734 TEX12

KEGG:hsa:56158 TEX12

Monarch:56158 TEX12

NCBI Gene:56158 TEX12

OMIM:605791 TEX12

UCSC:Q9BXU0 TEX12

Reference Transcript

RefSeq:NM_031275.4 TEX12

Other Identifiers

11740662_at

16731217

221438_PM_s_at

221438_s_at

3348989

3348991

3348992

3348993

3348994

3348995

3348996

42102_r_at

56158

7943859

A_14_P124806

A_23_P150362

GE80747

GO:0000711

GO:0000795

GO:0000801

GO:0005515

GO:0005694

GO:0007130

GO:0022414

GO:0043226

GO:0051321

HMNXSV003016802

ILMN_1803803

PH_hs_0027377

TC11003465.hg

g13775181_3p_s_at

Participates

as a component of

Central Element of Synaptonemal Complex [nucleoplasm] (Homo sapiens)

as an input of

Synapsis (Homo sapiens)

Cross References

OpenTargets

ENSG00000150783

ENSEMBL

ENST00000530752, ENSP00000436893, ENST00000280358, ENSP00000280358

HPA

ENSG00000150783-TEX12

PRO

Q9BXU0

Pharos - Targets

Q9BXU0

PDB

6HK9, 6R2F, 6HK8, 6YQF, 6R17

Interactors (30)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q96BZ8 LENG1	1	LENG1 [nucleoplasm] (R-HSA-9769590)	0.556	3
UniProt:P24863 CCNC	1	CCNC [nucleoplasm] (R-HSA-212418)	0.556	3
UniProt:A6NI15 MSGN1	1	MSGN1 [nucleoplasm] (R-HSA-9793376)	0.556	3
UniProt:O14901 KLF11			0.556	3
UniProt:Q14696 MESD			0.556	3
UniProt:O43482 OIP5	1	OIP5 [nucleoplasm] (R-HSA-606286)	0.556	3
UniProt:Q9Y2P0 ZN835			0.556	3
UniProt:Q0VD86 INCA1			0.556	3
UniProt:P01112 HRAS	20	S-Farn-Me-2xPalmS HRAS [plasma membrane] (R-HSA-9647912) proHRAS [cytosol] (R-HSA-9647765) S-Farn-proHRAS [endoplasmic reticulum membrane] (R-HSA-9647918) S-Farn-HRAS [endoplasmic reticulum membrane] (R-HSA-9647788) S-Farn-Me HRAS [endoplasmic reticulum membrane] (R-HSA-9647796) S-Farn-Me PalmS HRAS [Golgi membrane] (R-HSA-9647896) S-Farn-Me HRAS [plasma membrane] (R-HSA-9665052) HRAS [plasma membrane] (R-HSA-62717) HRAS G12C [plasma membrane] (R-HSA-9656561) HRAS G12D [plasma membrane] (R-HSA-9656564) HRAS K117N [plasma membrane] (R-HSA-9656603) HRAS G13S [plasma membrane] (R-HSA-9656574) HRAS G13D [plasma membrane] (R-HSA-9656572) HRAS G13V [plasma membrane] (R-HSA-9656579) HRAS K117R [plasma membrane] (R-HSA-9656010) HRAS G13C [plasma membrane] (R-HSA-9656008) HRAS T58I [plasma membrane] (R-HSA-9656014) HRAS G12S [plasma membrane] (R-HSA-6802343) HRAS G12V [plasma membrane] (R-HSA-6802350) HRAS G13R [plasma membrane] (R-HSA-6802368)	0.556	3
UniProt:Q14957 GRIN2C	3	GRIN2C [plasma membrane] (R-HSA-419560) GRIN2C [endoplasmic reticulum membrane] (R-HSA-9609761) p-Y-GRIN2C [plasma membrane] (R-HSA-9612189)	0.556	3
UniProt:P02489 CRYAA			0.556	3
UniProt:Q96KQ4 PPP1R13B	1	PPP1R13B [nucleoplasm] (R-HSA-6799775)	0.556	3
UniProt:Q96MY7 F161B			0.556	3
UniProt:Q8IZT9 FAM9C			0.556	3
UniProt:Q13153 PAK1	5	p-S144,T423-PAK1 [cytosol] (R-HSA-399819) PAK1 [cytosol] (R-HSA-162629) Active PAK1 [cytosol] (R-HSA-8964622) p-S144,T423-PAK1 [plasma membrane] (R-HSA-3928472) PAK1 [plasma membrane] (R-HSA-3928409)	0.556	3
UniProt:Q9UMX0 UBQLN1	1	UBQLN1 [cytosol] (R-HSA-8866006)	0.556	3
UniProt:Q14204 DYNC1H1	3	DYNC1H1 [cytosol] (R-HSA-380285) DYNC1H1 [azurophil granule lumen] (R-HSA-6799155) DYNC1H1 [extracellular region] (R-HSA-6806223)	0.556	3
UniProt:Q13155 AIMP2	1	AIMP2 [cytosol] (R-HSA-379576)	0.556	3
UniProt:Q9Y2W7 KCNIP3	2	KCNIP3 [plasma membrane] (R-HSA-5577044) KCNIP3 [nucleoplasm] (R-HSA-9640052)	0.556	3
UniProt:Q9BVL2 NUP58			0.556	3
UniProt:Q969G3 SMARCE1	1	SMARCE1 [nucleoplasm] (R-HSA-389258)	0.556	3
UniProt:Q86XR8-3 CEP57			0.556	3
UniProt:P10606 COX5B	1	COX5B [mitochondrial inner membrane] (R-HSA-164307)	0.556	3
UniProt:Q7Z3B4 NUP54	2	NUP54 [cytosol] (R-HSA-9634221) NUP54 [nuclear envelope] (R-HSA-157724)	0.556	3
UniProt:P63010-2 AP2B1			0.556	3
UniProt:Q96ES7 SGF29	1	SGF29 [nucleoplasm] (R-HSA-3662279)	0.556	3
UniProt:P51687 SUOX	1	SUOX [mitochondrial matrix] (R-HSA-1614570)	0.556	3
UniProt:Q6PIF2 SYCE2	1	SYCE2 [nucleoplasm] (R-HSA-912451)	0.556	5
UniProt:P22607 FGFR3	20	FGFR3(23-760)-TACC3(612-838) fusion [plasma membrane] (R-HSA-8853144) FGFR3(23-760)-BAIAP2L1(18-522) fusion [plasma membrane] (R-HSA-8853131) FGFR3(23-793)-TACC3(143-838) fusion [plasma membrane] (R-HSA-8853152) FGFR3(23-758)-TACC3(549-838) fusion [plasma membrane] (R-HSA-8853124) FGFR3(23-758)-TACC3(649-838) fusion [plasma membrane] (R-HSA-8853125) FGFR3(23-760)-TACC3(647-838) fusion [plasma membrane] (R-HSA-8853127) FGFR3 K650T [plasma membrane] (R-HSA-1614411) FGFR3 K650N [plasma membrane] (R-HSA-1614406) FGFR3 K650M [plasma membrane] (R-HSA-1614402) FGFR3 K650Q [plasma membrane] (R-HSA-1614410) FGFR3 A391E [plasma membrane] (R-HSA-1614390) FGFR3 K650E [plasma membrane] (R-HSA-1614400) FGFR3 G380R [plasma membrane] (R-HSA-1614398) FGFR3 G382D [plasma membrane] (R-HSA-2018740) FGFR3 805fs*141 [plasma membrane] (R-HSA-1614387) p-6Y-FGFR3 A391E [plasma membrane] (R-HSA-2065835) p-6Y-FGFR3 K650T [plasma membrane] (R-HSA-2032966) p-6Y-FGFR3 G382D [plasma membrane] (R-HSA-2032950) p-6Y-FGFR3 G380R [plasma membrane] (R-HSA-2032946) p-6Y-FGFR3 K650M [plasma membrane] (R-HSA-2032959)	0.556	3
UniProt:Q9Y5Z0 BACE2			0.556	3

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