ATR [nucleoplasm]

Stable Identifier
R-HSA-912443
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Serine/threonine-protein kinase ATR, ATR_HUMAN
Icon
ATR [nucleoplasm] icon
ATR [nucleoplasm] icon
Locations in the PathwayBrowser
Expand all
External Reference Information
External Reference
UniProt:Q13535 ATR
Gene Names
ATR, FRP1
Chain
chain:1-2644
Reference Genes
BioGPS Gene:545 ATR
COSMIC (genes):ATR ATR
CTD Gene:545 ATR
dbSNP Gene:545 ATR
ENSEMBL:ENSG00000175054 ATR
HGNC:882 ATR
KEGG:hsa:545 ATR
Monarch:545 ATR
NCBI Gene:545 ATR
OMIM:601215 ATR
UCSC:Q13535 ATR
Reference Transcript
Other Identifiers
11743838_a_at
16959985
16960046
209902_PM_at
209902_at
209903_PM_s_at
209903_s_at
233288_PM_at
233288_at
2698828
2698829
2698845
2698846
2698847
2698848
2698849
2698850
2698851
2698852
2698853
2698854
2698855
2698856
2698857
2698858
2698859
2698862
2698863
2698864
2698865
2698866
2698867
2698868
2698874
2698875
2698876
2698877
2698878
2698879
2698880
2698881
2698882
2698883
2698884
2698885
2698886
2698887
2698888
2698889
2698891
2698892
2698893
2698894
2698895
2698896
2698897
2698900
2698901
2698902
2698903
2698904
2698906
2698907
2698908
2698909
2698910
2698911
2698912
2698913
2698914
2698915
2698917
2698919
2698920
2698921
2698922
2698924
2698925
2698927
2698928
2698929
2698930
2698931
2698932
2698933
2698934
2698935
2698936
2698942
2698943
37229_at
545
8091190
86961_at
A_23_P136058
A_33_P3362498
GE59204
GO:0000077
GO:0000723
GO:0000781
GO:0003677
GO:0003824
GO:0004672
GO:0004674
GO:0005515
GO:0005524
GO:0005634
GO:0005635
GO:0005654
GO:0005694
GO:0005794
GO:0006139
GO:0006260
GO:0006281
GO:0006302
GO:0006325
GO:0006338
GO:0006974
GO:0008156
GO:0009410
GO:0009612
GO:0016301
GO:0016605
GO:0016740
GO:0018105
GO:0031297
GO:0032200
GO:0032212
GO:0032405
GO:0032407
GO:0034644
GO:0035979
GO:0036297
GO:0043226
GO:0043517
GO:0044818
GO:0046685
GO:0046777
GO:0051081
GO:0060255
GO:0061024
GO:0070198
GO:0070310
GO:0071480
GO:0080090
GO:0080135
GO:0090399
GO:0090734
GO:0097694
GO:0097695
GO:0106310
GO:0140096
GO:1900034
GO:1904884
GO:2000779
HMNXSV003021494
HMNXSV003045035
Hs.301081.0.S1_3p_at
ILMN_1660342
ILMN_1810385
ILMN_2277201
ILMN_2376771
PH_hs_0004476
TC03001854.hg
U49844_at
g1235901_3p_a_at
p11532
Participates
as a member of
as an input of
as a component of
Inferred To
mei-41 [nucleoplasm] (Drosophila melanogaster)
tel1 [nucleoplasm] (Schizosaccharomyces pombe)
Atr [nucleoplasm] (Mus musculus)
Atr [nucleoplasm] (Rattus norvegicus)
ATR [nucleoplasm] (Bos taurus)
ATR [nucleoplasm] (Canis familiaris)
ATR [nucleoplasm] (Gallus gallus)
ATR [nucleoplasm] (Sus scrofa)
Homologues of ATR [nucleoplasm] (Schizosaccharomyces pombe)
rad3 [nucleoplasm] (Schizosaccharomyces pombe)
atl-1 [nucleoplasm] (Caenorhabditis elegans)
Ghost homologue of ATR [nucleoplasm] (Xenopus tropicalis)
Cross References
RefSeq
Guide to Pharmacology - Targets
OpenTargets
ENSEMBL
ZINC - Substances
ZINC - Biogenic
ZINC target
PRO
GlyGen
PDB
ZINC - Metabolites
HPA
Pharos - Targets
Orphanet
ATR
ZINC - Predictions - Purchasable
HMDB Protein
Interactors (21)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:Q8WXE1 ATRIP  1 0.829 5
 UniProt:Q9BW66 CINP      0.612 5
 UniProt:Q9Y4R8 TELO2      0.597 4
 UniProt:P50750 CDK9  1 0.558 3
 UniProt:Q99459 CDC5L  1 0.544 3
 UniProt:P02724 GYPA  1 0.527 2
 UniProt:Q9ULX7 CA14  1 0.527 2
 UniProt:P06028 GYPB  1 0.527 2
 UniProt:P0DTC7 7a  5 0.527 2
 UniProt:P09619 PDGFRB  3 0.527 2
 UniProt:Q68D85 NCR3LG1  1 0.527 2
 UniProt:Q6EMK4 VASN      0.527 2
 UniProt:O60939 SCN2B  1 0.527 2
 UniProt:Q96IQ7 VSIG2      0.527 2
 UniProt:Q9NY72 SCN3B  1 0.527 2
 UniProt:Q86XK7 VSIG1      0.527 2
 UniProt:P32971 TNFSF8  1 0.527 3
 UniProt:Q9NZQ7 CD274  1 0.527 2
 UniProt:O95274 LYPD3  2 0.527 2
 UniProt:O43156 TTI1      0.499 2
 UniProt:Q9Y6K9 IKBKG  12 0.499 2
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