Synapsis

Stable Identifier
R-HSA-912505
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Formation of Central Elements of the Synaptonemal Complex
ReviewStatus
5/5
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Synapsis
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Initiation of recombination precedes and is required for synapsis (Roig et al. 2004). The synaptonemal complex forms when transverse filaments of SYCP1 link axial/lateral elements of sister chromatids to a central element comprising SYCE1, SYCE2, and other proteins (Tarsounas et al. 1997). The order of assembly is unknown.
Literature References
PubMed ID Title Journal Year
15235794 Female-specific features of recombinational double-stranded DNA repair in relation to synapsis and telomere dynamics in human oocytes

Liebe, B, Garcia, M, Egozcue, J, Scherthan, H, Roig, I, Cabero, L

Chromosoma 2004
9285814 Protein-protein interactions in the synaptonemal complex

Gasser, PJ, Pearlman, RE, Park, MS, Moens, PB, Tarsounas, M

Mol Biol Cell 1997
Participants
Input
Output
Participates
as an event of
Inferred From
Synapsis (Mus musculus)
Authored
May, B  (2010-07-03)
Reviewed
Bolcun-Filas, E  (2011-02-25)
Lyndaker, A  (2011-02-25)
Holloway, JK  (2011-02-05)
Schimenti, JC  (2011-02-05)
Strong, E  (2011-02-25)
Cohen, PE  (2011-02-05)
Created
May, B  (2010-07-09)
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