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CHMP2B [cytosol]
Stable Identifier
R-HSA-917695
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Charged multivesicular body protein 2b, CHM2B_HUMAN
Locations in the PathwayBrowser for interactor UniProt:Q9H444 CHMP4B
Expand all
Cell Cycle (Homo sapiens)
Cell Cycle, Mitotic (Homo sapiens)
M Phase (Homo sapiens)
Mitotic Metaphase and Anaphase (Homo sapiens)
Mitotic Anaphase (Homo sapiens)
Nuclear Envelope (NE) Reassembly (Homo sapiens)
Sealing of the nuclear envelope (NE) by ESCRT-III (Homo sapiens)
CHMP7 binds CHMP4B, which recruits other subunits of the ESCRT-III complex (Homo sapiens)
CHMP2B [cytosol] (Homo sapiens)
VPS4 mediates disassembly of ESCRTIII subunits to promote sealing of holes in the nuclear envelope (Homo sapiens)
CHMP2B [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9UQN3 CHMP2B
Gene Names
CHMP2B, CGI-84
Chain
initiator methionine:, chain:2-213
Reference Genes
BioGPS Gene:25978 CHMP2B
COSMIC (genes):CHMP2B CHMP2B
CTD Gene:25978 CHMP2B
dbSNP Gene:25978 CHMP2B
ENSEMBL:ENSG00000083937 CHMP2B
HGNC:24537 CHMP2B
KEGG:hsa:25978 CHMP2B
Monarch:25978 CHMP2B
NCBI Gene:25978 CHMP2B
OMIM:609512 CHMP2B
UCSC:Q9UQN3 CHMP2B
Reference Transcript
RefSeq:NM_001244644.1 CHMP2B
RefSeq:NM_014043.3 CHMP2B
Other Identifiers
11724746_at
11724747_a_at
11724748_at
16942906
202536_PM_at
202536_at
202537_PM_s_at
202537_s_at
202538_PM_s_at
202538_s_at
25978
2631848
2631849
2631850
2631851
2631852
2631859
2631860
2631862
2631863
2631864
2631865
2631866
2631867
2631868
2631869
2631870
2631871
2631872
2631873
39034_at
8081055
A_14_P116487
A_14_P116709
A_23_P212535
A_24_P114617
GE56036
GO:0000421
GO:0000776
GO:0000815
GO:0001778
GO:0005515
GO:0005643
GO:0005737
GO:0005764
GO:0005765
GO:0005768
GO:0005770
GO:0005771
GO:0005773
GO:0005828
GO:0005829
GO:0005886
GO:0006914
GO:0006997
GO:0007032
GO:0007034
GO:0007080
GO:0010824
GO:0014069
GO:0015031
GO:0016020
GO:0016192
GO:0016236
GO:0019076
GO:0019904
GO:0030496
GO:0031410
GO:0031468
GO:0031902
GO:0032509
GO:0032585
GO:0036258
GO:0039702
GO:0043162
GO:0043226
GO:0045296
GO:0045324
GO:0046761
GO:0050804
GO:0050877
GO:0050890
GO:0051469
GO:0061024
GO:0061763
GO:0061952
GO:0070050
GO:0070062
GO:0071985
GO:0090148
GO:0097352
GO:0098978
GO:0099159
GO:0099175
GO:1901673
GO:1902774
GO:1904903
GO:1904930
HMNXSV003028805
Hs.11449.0.S3_3p_at
ILMN_1741176
PH_hs_0001102
TC03000461.hg
g4929636_3p_a_at
g7661633_3p_a_at
Participates
as an output of
VPS4 mediates disassembly of ESCRTIII subunits to promote sealing of holes in the nuclear envelope (Homo sapiens)
as an input of
CHMP7 binds CHMP4B, which recruits other subunits of the ESCRT-III complex (Homo sapiens)
as a member of
CHMP2 [cytosol] (Homo sapiens)
Other forms of this molecule
CHMP2B [endosome membrane]
Inferred To
chmp2ba [cytosol]
(Danio rerio)
chmp2b [cytosol]
(Xenopus tropicalis)
Chmp2b [cytosol]
(Mus musculus)
Chmp2b [cytosol]
(Rattus norvegicus)
CHMP2B [cytosol]
(Bos taurus)
CHMP2B [cytosol]
(Caenorhabditis elegans)
CHMP2B [cytosol]
(Canis familiaris)
CHMP2B [cytosol]
(Drosophila melanogaster)
CHMP2B [cytosol]
(Gallus gallus)
CHMP2B [cytosol]
(Sus scrofa)
Cross References
RefSeq
NP_054762.2
,
NP_001231573.1
ENSEMBL
ENST00000471660
,
ENSP00000419998
,
ENST00000263780
,
ENSP00000263780
OpenTargets
ENSG00000083937
HPA
ENSG00000083937-CHMP2B
PRO
Q9UQN3
Pharos - Targets
Q9UQN3
GlyGen
Q9UQN3
Orphanet
CHMP2B
PDB
2JQK
Interactors (5)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9Y3E7 CHMP3
2
CHMP3 [endosome membrane]
(R-HSA-9631191)
CHMP3 [cytosol]
(R-HSA-917722)
0.592
2
UniProt:Q9H444 CHMP4B
2
CHMP4B [cytosol]
(R-HSA-917708)
CHMP4B [endosome membrane]
(R-HSA-9631202)
0.59
2
UniProt:P0C6X7-PRO_0000037316 REP
0.508
2
UniProt:P0C6X7-PRO_0000037309 REP
0.508
2
UniProt:Q9NYB0 TERF2IP
1
TERF2IP [nucleoplasm]
(R-HSA-174873)
0.508
2
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