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CHMP4C [cytosol]
Stable Identifier
R-HSA-917710
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Charged multivesicular body protein 4c, CHM4C_HUMAN
Locations in the PathwayBrowser for interactor UniProt:Q9H444 CHMP4B
Expand all
Cell Cycle (Homo sapiens)
Cell Cycle, Mitotic (Homo sapiens)
M Phase (Homo sapiens)
Mitotic Metaphase and Anaphase (Homo sapiens)
Mitotic Anaphase (Homo sapiens)
Nuclear Envelope (NE) Reassembly (Homo sapiens)
Sealing of the nuclear envelope (NE) by ESCRT-III (Homo sapiens)
CHMP7 binds CHMP4B, which recruits other subunits of the ESCRT-III complex (Homo sapiens)
CHMP4C [cytosol] (Homo sapiens)
VPS4 mediates disassembly of ESCRTIII subunits to promote sealing of holes in the nuclear envelope (Homo sapiens)
CHMP4C [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q96CF2 CHMP4C
Gene Names
CHMP4C, SHAX3
Chain
chain:1-233
Reference Genes
BioGPS Gene:92421 CHMP4C
COSMIC (genes):CHMP4C CHMP4C
CTD Gene:92421 CHMP4C
dbSNP Gene:92421 CHMP4C
ENSEMBL:ENSG00000164695 CHMP4C
HGNC:30599 CHMP4C
KEGG:hsa:92421 CHMP4C
Monarch:92421 CHMP4C
NCBI Gene:92421 CHMP4C
OMIM:610899 CHMP4C
UCSC:Q96CF2 CHMP4C
Reference Transcript
RefSeq:NM_152284.3 CHMP4C
Other Identifiers
11742978_at
17070331
226803_PM_at
226803_at
3105038
3105039
3105040
3105041
3105043
3105044
3105045
3105046
60500_at
8147057
92421
A_14_P118183
A_23_P432598
GE85411
GO:0000421
GO:0000776
GO:0000815
GO:0001778
GO:0005515
GO:0005643
GO:0005737
GO:0005765
GO:0005768
GO:0005771
GO:0005828
GO:0005829
GO:0005886
GO:0006900
GO:0006914
GO:0006997
GO:0007034
GO:0007080
GO:0009838
GO:0009898
GO:0010824
GO:0015031
GO:0016020
GO:0016192
GO:0016236
GO:0030496
GO:0031410
GO:0031468
GO:0031902
GO:0032466
GO:0032511
GO:0032585
GO:0036258
GO:0039702
GO:0042803
GO:0043162
GO:0043226
GO:0044878
GO:0046761
GO:0051469
GO:0061024
GO:0061763
GO:0061952
GO:0071985
GO:0090148
GO:0090543
GO:0090611
GO:0097352
GO:1901673
GO:1902774
GO:1904930
HMNXSV003027939
Hs.183861.0.S1_3p_at
ILMN_1711542
PH_hs_0010838
TC08000520.hg
Participates
as an output of
VPS4 mediates disassembly of ESCRTIII subunits to promote sealing of holes in the nuclear envelope (Homo sapiens)
as an input of
CHMP7 binds CHMP4B, which recruits other subunits of the ESCRT-III complex (Homo sapiens)
as a member of
CHMP4 [cytosol] (Homo sapiens)
Other forms of this molecule
CHMP4C [endosome membrane]
Inferred To
chmp4c [cytosol]
(Xenopus tropicalis)
snf7 [cytosol]
(Schizosaccharomyces pombe)
SNF7 [cytosol]
(Saccharomyces cerevisiae)
chmp4 [cytosol]
(Dictyostelium discoideum)
vps-32.1 [cytosol]
(Caenorhabditis elegans)
Chmp4c [cytosol]
(Mus musculus)
Chmp4c [cytosol]
(Rattus norvegicus)
CHMP4C [cytosol]
(Bos taurus)
CHMP4C [cytosol]
(Caenorhabditis elegans)
CHMP4C [cytosol]
(Canis familiaris)
CHMP4C [cytosol]
(Gallus gallus)
CHMP4C [cytosol]
(Sus scrofa)
Homologues of CHMP4C [cytosol]
(Caenorhabditis elegans)
Homologues of CHMP4C [cytosol]
(Schizosaccharomyces pombe)
chmp-7 [cytosol]
(Caenorhabditis elegans)
shrb [cytosol]
(Drosophila melanogaster)
cmp7 [cytosol]
(Schizosaccharomyces pombe)
Cross References
RefSeq
NP_689497.1
ENSEMBL
ENST00000297265
,
ENSP00000297265
OpenTargets
ENSG00000164695
HPA
ENSG00000164695-CHMP4C
PRO
Q96CF2
Pharos - Targets
Q96CF2
GlyGen
Q96CF2
PDB
3C3R
,
5MK3
,
5V3R
,
5WA1
Interactors (4)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q8WUM4 PDCD6IP
1
PDCD6IP [cytosol]
(R-HSA-917717)
0.667
3
UniProt:P40818 USP8
2
p-T945-USP8 [cytosol]
(R-HSA-1358714)
USP8 [cytosol]
(R-HSA-917720)
0.609
2
IntAct:EBI-10268368 128872
0.556
3
UniProt:Q9H444 CHMP4B
2
CHMP4B [cytosol]
(R-HSA-917708)
CHMP4B [endosome membrane]
(R-HSA-9631202)
0.547
2
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