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ESCRT-III [cytosol]
Stable Identifier
R-HSA-917723
Type
Complex
Species
Homo sapiens
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Autophagy (Homo sapiens)
Macroautophagy (Homo sapiens)
Autophagosome maturation (Homo sapiens)
ESCRT-III [cytosol] (Homo sapiens)
Cell Cycle (Homo sapiens)
Cell Cycle, Mitotic (Homo sapiens)
M Phase (Homo sapiens)
Mitotic Metaphase and Anaphase (Homo sapiens)
Mitotic Anaphase (Homo sapiens)
Nuclear Envelope (NE) Reassembly (Homo sapiens)
Sealing of the nuclear envelope (NE) by ESCRT-III (Homo sapiens)
CHMP7 binds CC2D1B (Homo sapiens)
LEM2D:ESCRT-III:IST1:CC2D1B [nuclear envelope] (Homo sapiens)
LEMD2:ESCRT-III:IST1 [nuclear envelope] (Homo sapiens)
ESCRT-III [cytosol] (Homo sapiens)
LEMD2:ESCRT-III:IST1 [nuclear envelope] (Homo sapiens)
ESCRT-III [cytosol] (Homo sapiens)
CHMP7 binds CHMP4B, which recruits other subunits of the ESCRT-III complex (Homo sapiens)
LEMD2:ESCRT-III:IST1 [nuclear envelope] (Homo sapiens)
ESCRT-III [cytosol] (Homo sapiens)
SPAST (spastin) binds the IST1 subunit of ESCRT-III at the sites of microtubule attachment to chromatin (Homo sapiens)
LEM2D:ESCRT-III:IST1:CC2D1B [nuclear envelope] (Homo sapiens)
LEMD2:ESCRT-III:IST1 [nuclear envelope] (Homo sapiens)
ESCRT-III [cytosol] (Homo sapiens)
LEM2D:ESCRT-III:IST1:CC2D1B:SPAST [nuclear envelope] (Homo sapiens)
LEM2D:ESCRT-III:IST1:CC2D1B [nuclear envelope] (Homo sapiens)
LEMD2:ESCRT-III:IST1 [nuclear envelope] (Homo sapiens)
ESCRT-III [cytosol] (Homo sapiens)
SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites (Homo sapiens)
LEM2D:ESCRT-III:IST1:CC2D1B:SPAST [nuclear envelope] (Homo sapiens)
LEM2D:ESCRT-III:IST1:CC2D1B [nuclear envelope] (Homo sapiens)
LEMD2:ESCRT-III:IST1 [nuclear envelope] (Homo sapiens)
ESCRT-III [cytosol] (Homo sapiens)
VPS4 binds ESCRT-III assemblies at nuclear envelope (NE) fenestrations (Homo sapiens)
LEM2D:ESCRT-III:IST1:CC2D1B:SPAST [nuclear envelope] (Homo sapiens)
LEM2D:ESCRT-III:IST1:CC2D1B [nuclear envelope] (Homo sapiens)
LEMD2:ESCRT-III:IST1 [nuclear envelope] (Homo sapiens)
ESCRT-III [cytosol] (Homo sapiens)
LEM2D:ESCRT-III:IST1:CC2D1B:SPAST:VPS4A [nuclear envelope] (Homo sapiens)
LEM2D:ESCRT-III:IST1:CC2D1B:SPAST [nuclear envelope] (Homo sapiens)
LEM2D:ESCRT-III:IST1:CC2D1B [nuclear envelope] (Homo sapiens)
LEMD2:ESCRT-III:IST1 [nuclear envelope] (Homo sapiens)
ESCRT-III [cytosol] (Homo sapiens)
VPS4 mediates disassembly of ESCRTIII subunits to promote sealing of holes in the nuclear envelope (Homo sapiens)
LEM2D:ESCRT-III:IST1:CC2D1B:SPAST:VPS4A [nuclear envelope] (Homo sapiens)
LEM2D:ESCRT-III:IST1:CC2D1B:SPAST [nuclear envelope] (Homo sapiens)
LEM2D:ESCRT-III:IST1:CC2D1B [nuclear envelope] (Homo sapiens)
LEMD2:ESCRT-III:IST1 [nuclear envelope] (Homo sapiens)
ESCRT-III [cytosol] (Homo sapiens)
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Viral Infection Pathways (Homo sapiens)
HCMV Infection (Homo sapiens)
HCMV Late Events (Homo sapiens)
HCMV Final Envelopment (Homo sapiens)
ESCRT Regulator Complex [cytosol] (Homo sapiens)
ESCRT-III [cytosol] (Homo sapiens)
HCMV Formation of Final Envelopment Complex (Homo sapiens)
ESCRT Regulator Complex [cytosol] (Homo sapiens)
ESCRT-III [cytosol] (Homo sapiens)
HIV Infection (Homo sapiens)
HIV Life Cycle (Homo sapiens)
Late Phase of HIV Life Cycle (Homo sapiens)
Budding and maturation of HIV virion (Homo sapiens)
HIV Virion Budding (Homo sapiens)
Virion Budding Complex [plasma membrane] (Homo sapiens)
ESCRT-III [cytosol] (Homo sapiens)
Recruitment Of HIV Virion Budding Machinery (Homo sapiens)
ESCRT-III [cytosol] (Homo sapiens)
Virion Budding Complex [plasma membrane] (Homo sapiens)
ESCRT-III [cytosol] (Homo sapiens)
SARS-CoV Infections (Homo sapiens)
SARS-CoV-1 Infection (Homo sapiens)
Translation of Replicase and Assembly of the Replication Transcription Complex (Homo sapiens)
Enhanced autophagosome formation (Homo sapiens)
ESCRT-III [cytosol] (Homo sapiens)
SARS-CoV-2 Infection (Homo sapiens)
Early SARS-CoV-2 Infection Events (Homo sapiens)
Translation of Replicase and Assembly of the Replication Transcription Complex (Homo sapiens)
Enhanced autophagosome formation (Homo sapiens)
ESCRT-III [cytosol] (Homo sapiens)
Programmed Cell Death (Homo sapiens)
Regulated Necrosis (Homo sapiens)
Pyroptosis (Homo sapiens)
GSDMD forms ring‐shaped oligomers (Homo sapiens)
ESCRT-III [cytosol] (Homo sapiens)
Vesicle-mediated transport (Homo sapiens)
Membrane Trafficking (Homo sapiens)
Endosomal Sorting Complex Required For Transport (ESCRT) (Homo sapiens)
ESCRT Disassembly (Homo sapiens)
ESCRT-III/Cargo Complex [endosome membrane] (Homo sapiens)
ESCRT-III [cytosol] (Homo sapiens)
MVB Vesicle Formation (Homo sapiens)
ESCRT-III [cytosol] (Homo sapiens)
ESCRT-III/Cargo Complex [endosome membrane] (Homo sapiens)
ESCRT-III [cytosol] (Homo sapiens)
Participants
components
CHMP2 [cytosol]
(Homo sapiens)
CHMP3 [cytosol]
(Homo sapiens)
CHMP4 [cytosol]
(Homo sapiens)
CHMP6 [cytosol]
(Homo sapiens)
CHMP7 [cytosol]
(Homo sapiens)
Participates
as an input of
MVB Vesicle Formation (Homo sapiens)
Recruitment Of HIV Virion Budding Machinery (Homo sapiens)
as a component of
ESCRT-III/Cargo Complex [endosome membrane] (Homo sapiens)
Virion Budding Complex [plasma membrane] (Homo sapiens)
ESCRT Regulator Complex [cytosol] (Homo sapiens)
LEMD2:ESCRT-III:IST1 [nuclear envelope] (Homo sapiens)
This entity regulates
Negatively
GSDMD forms ring‐shaped oligomers
(Homo sapiens)
Positively
Enhanced autophagosome formation
(Homo sapiens)
Enhanced autophagosome formation
(Homo sapiens)
Autophagosome maturation
(Homo sapiens)
Inferred To
ESCRT-III [cytosol]
(Bos taurus)
ESCRT-III [cytosol]
(Caenorhabditis elegans)
ESCRT-III [cytosol]
(Canis familiaris)
ESCRT-III [cytosol]
(Danio rerio)
ESCRT-III [cytosol]
(Dictyostelium discoideum)
ESCRT-III [cytosol]
(Drosophila melanogaster)
ESCRT-III [cytosol]
(Gallus gallus)
ESCRT-III [cytosol]
(Mus musculus)
ESCRT-III [cytosol]
(Rattus norvegicus)
ESCRT-III [cytosol]
(Saccharomyces cerevisiae)
ESCRT-III [cytosol]
(Schizosaccharomyces pombe)
ESCRT-III [cytosol]
(Sus scrofa)
ESCRT-III [cytosol]
(Xenopus tropicalis)
Cross References
ComplexPortal
CPX-329
© 2024
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