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CHMP6 [cytosol]
Stable Identifier
R-HSA-917736
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Charged multivesicular body protein 6, CHMP6_HUMAN
Icon
Locations in the PathwayBrowser for interactor UniProt:Q9H444 CHMP4B
Expand all
Cell Cycle (Homo sapiens)
Cell Cycle, Mitotic (Homo sapiens)
M Phase (Homo sapiens)
Mitotic Metaphase and Anaphase (Homo sapiens)
Mitotic Anaphase (Homo sapiens)
Nuclear Envelope (NE) Reassembly (Homo sapiens)
Sealing of the nuclear envelope (NE) by ESCRT-III (Homo sapiens)
CHMP7 binds CHMP4B, which recruits other subunits of the ESCRT-III complex (Homo sapiens)
CHMP6 [cytosol] (Homo sapiens)
VPS4 mediates disassembly of ESCRTIII subunits to promote sealing of holes in the nuclear envelope (Homo sapiens)
CHMP6 [cytosol] (Homo sapiens)
Vesicle-mediated transport (Homo sapiens)
Membrane Trafficking (Homo sapiens)
Endosomal Sorting Complex Required For Transport (ESCRT) (Homo sapiens)
ESCRT Disassembly (Homo sapiens)
CHMP6 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q96FZ7 CHMP6
Gene Names
CHMP6, VPS20
Chain
initiator methionine:, chain:2-201
Reference Genes
BioGPS Gene:79643 CHMP6
COSMIC (genes):CHMP6 CHMP6
CTD Gene:79643 CHMP6
dbSNP Gene:79643 CHMP6
ENSEMBL:ENSG00000176108 CHMP6
HGNC:25675 CHMP6
KEGG:hsa:79643 CHMP6
Monarch:79643 CHMP6
NCBI Gene:79643 CHMP6
OMIM:610901 CHMP6
UCSC:Q96FZ7 CHMP6
Reference Transcript
RefSeq:NM_024591.4 CHMP6
Other Identifiers
11718589_at
11718590_at
16838737
218743_PM_at
218743_at
3737648
3737649
3737650
3737655
3737656
3737657
3737658
3737659
3737660
3737661
3737665
3737666
3737667
3737668
3737669
3737670
3737671
3737672
3737676
56326_at
79643
8010550
A_14_P134798
A_23_P10156
GE56976
GO:0000421
GO:0000776
GO:0000815
GO:0001778
GO:0005515
GO:0005643
GO:0005765
GO:0005768
GO:0005771
GO:0005828
GO:0005829
GO:0005886
GO:0006900
GO:0006914
GO:0006997
GO:0007034
GO:0007080
GO:0007175
GO:0010008
GO:0012505
GO:0015031
GO:0016020
GO:0016192
GO:0016236
GO:0030496
GO:0031410
GO:0031468
GO:0031902
GO:0032511
GO:0032585
GO:0036258
GO:0039702
GO:0042176
GO:0043162
GO:0043226
GO:0044877
GO:0046761
GO:0051469
GO:0061024
GO:0061763
GO:0061952
GO:0065003
GO:0070062
GO:0071985
GO:0090148
GO:0097352
GO:1901673
GO:1902774
GO:1904902
GO:1904930
HMNXSV003029105
HMNXSV003043544
ILMN_1706397
ILMN_1731609
PH_hs_0002006
TC17000922.hg
g13375782_3p_at
Participates
as an output of
ESCRT Disassembly (Homo sapiens)
VPS4 mediates disassembly of ESCRTIII subunits to promote sealing of holes in the nuclear envelope (Homo sapiens)
as an input of
CHMP7 binds CHMP4B, which recruits other subunits of the ESCRT-III complex (Homo sapiens)
as a component of
ESCRT-III [cytosol] (Homo sapiens)
Other forms of this molecule
CHMP6 [endosome membrane]
Inferred To
CHMP6 [cytosol]
(Bos taurus)
CHMP6 [cytosol]
(Gallus gallus)
CHMP6 [cytosol]
(Sus scrofa)
Chmp6 [cytosol]
(Mus musculus)
Chmp6 [cytosol]
(Rattus norvegicus)
chmp6 [cytosol]
(Danio rerio)
chmp6 [cytosol]
(Dictyostelium discoideum)
chmp6 [cytosol]
(Xenopus tropicalis)
vps20 [cytosol]
(Schizosaccharomyces pombe)
Vps20 [cytosol]
(Drosophila melanogaster)
Ghost homologue of CHMP6 [cytosol]
(Canis familiaris)
VPS20 [cytosol]
(Saccharomyces cerevisiae)
vps-20 [cytosol]
(Caenorhabditis elegans)
Cross References
RefSeq
NP_078867.2
ENSEMBL
ENST00000325167
,
ENSP00000317468
OpenTargets
ENSG00000176108
HPA
ENSG00000176108-CHMP6
PRO
Q96FZ7
Pharos - Targets
Q96FZ7
PDB
3HTU
,
2K3W
Interactors (5)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9BRG1 VPS25
1
VPS25 [cytosol]
(R-HSA-917697)
0.806
8
UniProt:O14656-2 TOR1A
0.556
3
UniProt:P50570-2 DNM2
0.556
3
UniProt:Q16637 SMN1
2
SMN1 [nucleoplasm]
(R-HSA-191892)
SMN1 [cytosol]
(R-HSA-191839)
0.556
3
UniProt:Q9H444 CHMP4B
2
CHMP4B [cytosol]
(R-HSA-917708)
CHMP4B [endosome membrane]
(R-HSA-9631202)
0.547
2
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