GABA loaded synaptic vesicle Docking and Priming

Stable Identifier
R-HSA-917744
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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SVG |   | PPTX  | SBGN
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GABA loaded synaptic vesicles are docked at the presynaptic terminal membrane by a number of proteins including Rab3a, RIM (Rab3a interaction protein) and Munc 13. The docked GABA vesicles are primed by the SNARE complex that includes synaptobrevin, SNAP 25 and syntaxin1.

Literature References
PubMed ID Title Journal Year
16722236 The role of SNARE proteins in trafficking and function of neurotransmitter transporters

Quick, MW

Handb Exp Pharmacol 2006
Participants
Participates
Catalyst Activity

SNARE binding activity of GABA Loaded synaptic vesicle [clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane]

Orthologous Events
Cross References
Target Pathogen
Authored
Reviewed
Created
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