Reactome | RGS4 [plasma membrane]

RGS4 [plasma membrane]

Stable Identifier

R-HSA-921135

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Regulator of G-protein signaling 4, RGS4_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P49798 RGS4

Gene Names

RGS4

Chain

chain:1-205

Reference Genes

BioGPS Gene:5999 RGS4

COSMIC (genes):RGS4 RGS4

CTD Gene:5999 RGS4

dbSNP Gene:5999 RGS4

ENSEMBL:ENSG00000117152 RGS4

HGNC:10000 RGS4

KEGG:hsa:5999 RGS4

Monarch:5999 RGS4

NCBI Gene:5999 RGS4

OMIM:602516 RGS4

UCSC:P49798 RGS4

Reference Transcript

Other Identifiers

11732993_a_at

11732994_a_at

11732995_a_at

11741572_a_at

16673126

204337_PM_at

204337_at

204338_PM_s_at

204338_s_at

204339_PM_s_at

204339_s_at

2364383

2364384

2364385

2364386

2364387

2364388

2364389

2364390

2364391

2364392

2364393

2364394

2364395

2364396

34272_at

34273_at

47486_at

5999

7906919

A_23_P200737

A_23_P433855

GE80427

GE87372

GO:0001965

GO:0001975

GO:0003824

GO:0003924

GO:0005096

GO:0005516

GO:0005634

GO:0005737

GO:0005886

GO:0007186

GO:0008277

GO:0009968

GO:0010460

GO:0016787

GO:0019901

GO:0032991

GO:0042220

GO:0043226

GO:0045471

GO:0045744

GO:0048856

GO:0051924

GO:0060160

GO:0061052

GO:0098772

GO:0110053

GO:1900924

GO:1901379

GO:1901380

GO:1990791

GO:2000463

HMNXSV003013512

Hs.227571.0.S3_3p_at

ILMN_1758067

PH_hs_0029997

TC01001427.hg

U27768_at

g11184227_3p_a_at

g12653888_3p_a_at

Participates

as a member of

Inferred To

Homologues of RGS4 [plasma membrane] (Caenorhabditis elegans)

Homologues of RGS4 [plasma membrane] (Dictyostelium discoideum)

Homologues of RGS4 [plasma membrane] (Saccharomyces cerevisiae)

rgs-10 [plasma membrane] (Caenorhabditis elegans)

rgs-6 [plasma membrane] (Caenorhabditis elegans)

Rgs4 [plasma membrane] (Mus musculus)

Rgs4 [plasma membrane] (Rattus norvegicus)

SST2 [plasma membrane] (Saccharomyces cerevisiae)

rgs-3 [plasma membrane] (Caenorhabditis elegans)

RGS2 [plasma membrane] (Saccharomyces cerevisiae)

rgs4 [plasma membrane] (Danio rerio)

rgs4 [plasma membrane] (Xenopus tropicalis)

rgs1 [plasma membrane] (Schizosaccharomyces pombe)

rgs-8.1 [plasma membrane] (Caenorhabditis elegans)

rgs-11 [plasma membrane] (Caenorhabditis elegans)

rgs-4 [plasma membrane] (Caenorhabditis elegans)

RGS4 [plasma membrane] (Bos taurus)

RGS4 [plasma membrane] (Canis familiaris)

RGS4 [plasma membrane] (Dictyostelium discoideum)

RGS4 [plasma membrane] (Gallus gallus)

RGS4 [plasma membrane] (Sus scrofa)

rgs-7 [plasma membrane] (Caenorhabditis elegans)

rgs-9 [plasma membrane] (Caenorhabditis elegans)

Cross References

Guide to Pharmacology - Targets

2811

ENSEMBL

ENST00000367909, ENST00000367908, ENSP00000433261, ENSG00000117152, ENSP00000356882, ENST00000421743, ENST00000367906, ENST00000527809, ENSP00000356885, ENSP00000356884, ENSP00000397181

OpenTargets

ENSG00000117152

GeneCards

RGS4

HPA

ENSG00000117152-RGS4

ZINC - Substances

RGS4_HUMAN

ZINC target

P49798

PRO

P49798

Pharos - Targets

P49798

ZINC - Predictions - Purchasable

RGS4_HUMAN

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P00533 EGFR	20	p-6Y-EGFR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869138) p-5Y-EGFRvIII [plasma membrane] (R-HSA-1248649) EGFRvIII [plasma membrane] (R-HSA-1214162) p-6Y-EGFR E746_A750del;T790M [plasma membrane] (R-HSA-1182985) p-6Y-EGFR L858R;T790M [plasma membrane] (R-HSA-1182984) p-6Y-EGFR A767_V769dup [plasma membrane] (R-HSA-1996343) p-6Y-EGFR N771_H773dup [plasma membrane] (R-HSA-1996342) p-6Y-EGFR K739_I744dup [plasma membrane] (R-HSA-1996346) p-6Y-EGFR D770_N771insNPG [plasma membrane] (R-HSA-1996335) p-6Y-EGFR E746_A750del [plasma membrane] (R-HSA-1181214) p-6Y-EGFR L858R [plasma membrane] (R-HSA-1173211) p-6Y-EGFR G719S [plasma membrane] (R-HSA-1169417) p-6Y-EGFR L747_P753delinsS [plasma membrane] (R-HSA-1228038) p-6Y-EGFR L747_A750delinsP [plasma membrane] (R-HSA-1228044) p-6Y-EGFR L747_T751del [plasma membrane] (R-HSA-1228041) p-6Y-EGFR L747_S752del [plasma membrane] (R-HSA-1228040) p-6Y-EGFR L747_T751delinsP [plasma membrane] (R-HSA-1228042) p-6Y-EGFR E746_T751delinsA [plasma membrane] (R-HSA-1228037) p-6Y-EGFR E746_S752delinsV [plasma membrane] (R-HSA-1228039) p-6Y-EGFR L861Q [plasma membrane] (R-HSA-1177541)	0.553	2

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