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SMG9 [cytosol]
Stable Identifier
R-HSA-927812
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Protein SMG9, SMG9_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism of RNA (Homo sapiens)
Nonsense-Mediated Decay (NMD) (Homo sapiens)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Homo sapiens)
SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Homo sapiens)
SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Homo sapiens)
SMG1:SMG8:SMG9 Complex [cytosol] (Homo sapiens)
SMG9 [cytosol] (Homo sapiens)
SMG1:UPF1:EJC:Translated mRNP [cytosol] (Homo sapiens)
SMG1:SMG8:SMG9 Complex [cytosol] (Homo sapiens)
SMG9 [cytosol] (Homo sapiens)
UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex (Homo sapiens)
SMG1:SMG8:SMG9 Complex [cytosol] (Homo sapiens)
SMG9 [cytosol] (Homo sapiens)
SMG1:UPF1:EJC:Translated mRNP [cytosol] (Homo sapiens)
SMG1:SMG8:SMG9 Complex [cytosol] (Homo sapiens)
SMG9 [cytosol] (Homo sapiens)
p-4S-UPF1 recruits SMG5, SMG7, SMG6, PNRC2, DCP1A, and PP2A (Homo sapiens)
SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Homo sapiens)
SMG1:SMG8:SMG9 Complex [cytosol] (Homo sapiens)
SMG9 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9H0W8 SMG9
Gene Names
SMG9, C19orf61
Chain
initiator methionine:, chain:2-520
Reference Genes
BioGPS Gene:56006 SMG9
COSMIC (genes):SMG9 SMG9
CTD Gene:56006 SMG9
dbSNP Gene:56006 SMG9
ENSEMBL:ENSG00000105771 SMG9
HGNC:25763 SMG9
Monarch:56006 SMG9
NCBI Gene:56006 SMG9
OMIM:613176 SMG9
UCSC:Q9H0W8 SMG9
Reference Transcript
RefSeq:NM_019108.3 SMG9
Other Identifiers
11717649_a_at
11717650_at
16873071
221335_PM_x_at
221335_x_at
223188_PM_at
223188_at
233990_PM_at
233990_at
3864595
3864596
3864598
3864599
3864600
3864602
3864603
3864604
3864605
3864606
3864607
3864608
3864609
3864610
3864611
3864612
3864613
3864616
3864617
3864618
3864619
3864620
3864621
3864622
3864623
3864624
3864625
3864626
3864627
3864632
3864634
3864635
3864636
48017_at
56006
8037389
A_23_P56127
GE53993
GE843961
GO:0000184
GO:0001654
GO:0001701
GO:0005515
GO:0005829
GO:0007420
GO:0007507
GO:0016071
GO:0042802
GO:0043066
GO:0048856
HMNXSV003035809
HMNXSV003053048
Hs.10116.2.S1_3p_at
ILMN_1737005
PH_hs_0001044
TC19001594.hg
g10092658_3p_a_at
g12052737_3p_at
Participates
as a component of
SMG1:SMG8:SMG9 Complex [cytosol] (Homo sapiens)
Inferred To
Ghost homologue of SMG9 [cytosol]
(Danio rerio)
Ghost homologue of SMG9 [cytosol]
(Gallus gallus)
Ghost homologue of SMG9 [cytosol]
(Plasmodium falciparum)
Ghost homologue of SMG9 [cytosol]
(Saccharomyces cerevisiae)
Ghost homologue of SMG9 [cytosol]
(Schizosaccharomyces pombe)
Smg9 [cytosol]
(Mus musculus)
Smg9 [cytosol]
(Rattus norvegicus)
smg9 [cytosol]
(Xenopus tropicalis)
SMG9 [cytosol]
(Bos taurus)
SMG9 [cytosol]
(Canis familiaris)
SMG9 [cytosol]
(Dictyostelium discoideum)
SMG9 [cytosol]
(Drosophila melanogaster)
SMG9 [cytosol]
(Sus scrofa)
smg-9 [cytosol]
(Caenorhabditis elegans)
Cross References
ENSEMBL
ENST00000270066
,
ENSP00000471398
,
ENST00000601170
,
ENSP00000270066
OpenTargets
ENSG00000105771
HPA
ENSG00000105771-SMG9
PRO
Q9H0W8
Pharos - Targets
Q9H0W8
GlyGen
Q9H0W8
PDB
6SYT
,
7PW8
,
6L54
,
7PW7
,
8FE7
,
6Z3R
,
7PW4
,
7PW9
,
7PW5
Interactors (7)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q12933 TRAF2
5
TRAF2 [cytosol]
(R-HSA-66370)
PolyUb-TRAF2 [cytosol]
(R-HSA-6782848)
K63polyUb-TRAF2 [cytosol]
(R-HSA-8862193)
K63polyUb-TRAF2 [nucleoplasm]
(R-HSA-8862194)
TRAF2 [nucleoplasm]
(R-HSA-8862199)
0.718
6
UniProt:Q6ZPD8 DGAT2L6
1
DGAT2L6 [endoplasmic reticulum membrane]
(R-HSA-8848588)
0.556
3
UniProt:Q6DKK2 TTC19
1
TTC19 [mitochondrial inner membrane]
(R-HSA-9906047)
0.556
3
UniProt:P14373 TRIM27
2
TRIM27 [cytosol]
(R-HSA-8851002)
TRIM27 [nucleoplasm]
(R-HSA-2997690)
0.556
3
UniProt:P53365 ARFIP2
1
ARFIP2 [cytosol]
(R-HSA-6813848)
0.556
3
UniProt:Q9BRV3 SLC50A1
1
SLC50A1 [plasma membrane]
(R-HSA-5216211)
0.556
3
UniProt:Q08379 GOLGA2
3
p-S37-GOLGA2 [Golgi membrane]
(R-HSA-2172179)
GOLGA2 [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-HSA-2167933)
GOLGA2 [Golgi membrane]
(R-HSA-6808764)
0.556
3
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