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RNF216 [cytosol]
Stable Identifier
R-HSA-936043
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
TRIAD3A, E3 ubiquitin-protein ligase RNF216, RN216_HUMAN
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
DDX58/IFIH1-mediated induction of interferon-alpha/beta (Homo sapiens)
Negative regulators of DDX58/IFIH1 signaling (Homo sapiens)
Negative regulation of DDX58/IFIH1 signaling by RNF216 (Homo sapiens)
RNF216 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9NWF9 RNF216
Gene Names
RNF216, TRIAD3, UBCE7IP1, ZIN
Chain
chain:1-866
Reference Genes
BioGPS Gene:54476 RNF216
COSMIC (genes):RNF216 RNF216
CTD Gene:54476 RNF216
dbSNP Gene:54476 RNF216
ENSEMBL:ENSG00000011275 RNF216
ENSEMBL_homo_sapiens_GENE:ENSG00000011275.19 RNF216
HGNC:21698 RNF216
KEGG Gene (Homo sapiens):54476 RNF216
Monarch:54476 RNF216
NCBI Gene:54476 RNF216
OMIM:609948 RNF216
UCSC:Q9NWF9 RNF216
Reference Transcript
RefSeq:XM_017012365.1 RNF216
RefSeq:NM_207111.3 RNF216
RefSeq:NM_207116.2 RNF216
RefSeq:XM_005249785.2 RNF216
RefSeq:XM_011515436.1 RNF216
RefSeq:XM_017012363.1 RNF216
Other Identifiers
11723735_a_at
11723736_a_at
11723737_x_at
11750492_a_at
11750493_x_at
17054852
218425_PM_at
218425_at
218426_PM_s_at
218426_s_at
227065_PM_at
227065_at
2988416
2988419
2988421
2988422
3036986
3036987
3036988
3036989
3036990
3036991
3036992
3036993
3036994
3036995
3036996
3036997
3036998
3036999
3037000
3037004
3037010
3037015
3037046
3037047
3037048
3037049
3037050
3037051
3037052
3037054
3037055
3037056
3037057
3037059
3037060
3037061
3037062
3037063
3037066
3037068
3037069
3037071
37477_at
48511_at
54476
54606_at
61970_at
8137986
A_23_P42724
A_24_P235131
A_33_P3341365
GE55652
GO:0003824
GO:0005515
GO:0005634
GO:0005654
GO:0005737
GO:0005829
GO:0006915
GO:0008270
GO:0012501
GO:0016567
GO:0016740
GO:0030136
GO:0030163
GO:0031410
GO:0032480
GO:0032648
GO:0036211
GO:0043161
GO:0043226
GO:0046872
GO:0050691
GO:0061630
GO:0070936
GO:0098542
GO:0140096
HMNXSV003018032
HMNXSV003040789
Hs.82985.1.A1_3p_at
Hs.82985.1.A1_3p_x_at
ILMN_1729980
ILMN_1802371
PH_hs_0022436
TC07001121.hg
g12653980_3p_at
g9507204_3p_a_at
Cross References
RefSeq
NP_996999.1
,
XP_016867852.1
,
NP_996994.1
,
XP_016867854.1
,
XP_005249842.1
,
XP_011513738.1
OpenTargets
ENSG00000011275
IntEnz
2.3.2.27
GeneCards
Q9NWF9
HPA
ENSG00000011275-RNF216
Ensembl
ENST00000389902
,
ENSG00000011275
,
ENSP00000374552
,
ENSP00000404602
,
ENST00000425013
PRO
Q9NWF9
Pharos - Targets
Q9NWF9
Orphanet
22215
PDB
8EB0
,
7M4N
,
7M4M
,
7M4O
Interactors (15)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P57075-2 UBASH3A
0.556
3
UniProt:Q5VVQ6 YOD1
1
YOD1 [cytosol]
(R-HSA-6781909)
0.556
3
UniProt:O75808 CAPN15
1
CAPN15 [cytosol]
(R-HSA-8848636)
0.556
3
UniProt:Q8N3F0 MTURN
0.556
3
UniProt:P45974-2 USP5
0.556
3
UniProt:Q92567-2 FAM168A
0.556
3
UniProt:Q9BSL1 UBAC1
1
UBAC1 [cytosol]
(R-HSA-8851644)
0.556
3
UniProt:O15037 KHNYN
0.556
3
UniProt:Q8TF42 UBS3B
0.556
3
UniProt:P21580 TNFAIP3
1
TNFAIP3 [cytosol]
(R-HSA-688989)
0.556
3
UniProt:O14933 UBE2L6
2
UBE2L6 [cytosol]
(R-HSA-936014)
UBE2L6 [nucleoplasm]
(R-HSA-5653666)
0.556
3
UniProt:P68036 UBE2L3
4
Ub-C86-UBE2L3 [nucleoplasm]
(R-HSA-8864226)
UBE2L3 [nucleoplasm]
(R-HSA-8852056)
UBE2L3 [cytosol]
(R-HSA-947631)
Ub-C86-UBE2L3 [cytosol]
(R-HSA-8864201)
0.556
3
UniProt:Q14149 MORC3
0.556
3
UniProt:Q8N6M9 ZFN2A
0.556
3
UniProt:Q96CV9 OPTN
6
OPTN [recycling endosome membrane]
(R-HSA-8854141)
p-S177-OPTN [nucleoplasm]
(R-HSA-2562595)
p-S177-OPTN [cytosol]
(R-HSA-2562525)
OPTN [Golgi membrane]
(R-HSA-2161111)
OPTN [cytosol]
(R-HSA-9687907)
p-S177,S473,S513-OPTN [cytosol]
(R-HSA-9687840)
0.556
3
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