Reactome | CHUK:IKBKB:IKBKG:K63pUb-RIP1:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane]

Stable Identifier

R-HSA-937030

Type

Complex

Species

Homo sapiens

Compartment

endosome membrane

Synonyms

activated TLR4:TRIF:K63pUb-RIP1:IKK complex

Locations in the PathwayBrowser

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Literature References

PubMed ID	Title	Journal	Year
16115877	Rip1 mediates the Trif-dependent toll-like receptor 3- and 4-induced NF-{kappa}B activation but does not contribute to interferon regulatory factor 3 activation Fitzgerald, KA, Cusson-Hermance, N, Khurana, S, Kelliher, MA, Lee, TH	J Biol Chem	2005
15814722	Apoptosis induced by the toll-like receptor adaptor TRIF is dependent on its receptor interacting protein homotypic interaction motif Offermann, MK, Kaiser, WJ	J Immunol	2005
15064760	RIP1 is an essential mediator of Toll-like receptor 3-induced NF-kappa B Blancheteau, V, Meylan, E, Burns, K, Kelliher, M, Tschopp, J, Martinon, F, Hofmann, K	Nat Immunol	2004

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