p-IRAK2:p-IRAK4:oligo-MyD88:TIRAP:activated TLR [plasma membrane]

Stable Identifier
R-HSA-937055
Type
Complex
Species
Homo sapiens
Related Species
Chlamydia trachomatis, Neisseria meningitidis serogroup B
Compartment
Locations in the PathwayBrowser
Literature References
PubMed ID Title Journal Year
19679662 Identification of critical residues of the MyD88 death domain involved in the recruitment of downstream kinases

Ruggiero, V, Gallo, G, Fantò, N, Loiarro, M, De Santis, R, Carminati, P, Sette, C

J Biol Chem 2009
20485341 Helical assembly in the MyD88-IRAK4-IRAK2 complex in TLR/IL-1R signalling

Lo, YC, Lin, SC, Wu, H

Nature 2010
Participants
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