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MX1 [cytosol]
Stable Identifier
R-HSA-947489
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
MXB, Interferon-induced GTP-binding protein Mx1, MX1_HUMAN
Icon
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Cytokine Signaling in Immune system (Homo sapiens)
Interferon Signaling (Homo sapiens)
Antiviral mechanism by IFN-stimulated genes (Homo sapiens)
ISG15 antiviral mechanism (Homo sapiens)
ISGylation of host proteins (Homo sapiens)
ISG15 targets [cytosol] (Homo sapiens)
Mx GTPases [cytosol] (Homo sapiens)
MX1 [cytosol] (Homo sapiens)
ISGylated host proteins [cytosol] (Homo sapiens)
ISG15 targets [cytosol] (Homo sapiens)
Mx GTPases [cytosol] (Homo sapiens)
MX1 [cytosol] (Homo sapiens)
Regulation of protein ISGylation by ISG15 deconjugating enzyme USP18 (Homo sapiens)
ISG15 targets [cytosol] (Homo sapiens)
Mx GTPases [cytosol] (Homo sapiens)
MX1 [cytosol] (Homo sapiens)
ISGylated host proteins [cytosol] (Homo sapiens)
ISG15 targets [cytosol] (Homo sapiens)
Mx GTPases [cytosol] (Homo sapiens)
MX1 [cytosol] (Homo sapiens)
Interferon alpha/beta signaling (Homo sapiens)
Expression of IFN-induced genes (Homo sapiens)
Mx GTPases [cytosol] (Homo sapiens)
MX1 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:P20591 MX1
Gene Names
MX1
Chain
chain:1-662, initiator methionine:, chain:2-662
Reference Genes
BioGPS Gene:4599 MX1
COSMIC (genes):MX1 MX1
CTD Gene:4599 MX1
dbSNP Gene:4599 MX1
ENSEMBL:ENSG00000157601 MX1
ENSEMBL_homo_sapiens_GENE:ENSG00000157601.15 MX1
HGNC:7532 MX1
KEGG Gene (Homo sapiens):4599 MX1
Monarch:4599 MX1
NCBI Gene:4599 MX1
OMIM:147150 MX1
UCSC:P20591 MX1
Reference Transcript
RefSeq:XM_005260980.2 MX1
RefSeq:XM_005260978.4 MX1
RefSeq:XM_011529568.2 MX1
RefSeq:XM_017028350.1 MX1
RefSeq:NM_001144925.2 MX1
RefSeq:NM_001178046.2 MX1
RefSeq:XM_005260979.2 MX1
RefSeq:NM_002462.4 MX1
RefSeq:XM_005260981.2 MX1
RefSeq:XM_005260982.2 MX1
RefSeq:XM_017028349.1 MX1
RefSeq:NM_001282920.1 MX1
Other Identifiers
11716167_a_at
16923031
202086_PM_at
202086_at
37014_at
3739156
3922056
3922098
3922099
3922101
3922102
3922103
3922105
3922106
3922107
3922109
3922113
3922114
3922115
3922116
3922117
3922118
3922120
3922121
3922123
3922125
3922126
3922127
3922128
3922129
3922130
3922131
3922135
3922137
3922140
3922143
3922144
3922147
3922149
3922150
3922151
3922153
3922154
4599
8068713
A_23_P17663
GE79032
GO:0000166
GO:0002376
GO:0003824
GO:0003924
GO:0005515
GO:0005525
GO:0005634
GO:0005635
GO:0005737
GO:0005783
GO:0005789
GO:0005829
GO:0005856
GO:0005874
GO:0006915
GO:0006952
GO:0007165
GO:0008017
GO:0008092
GO:0009615
GO:0012501
GO:0016020
GO:0016787
GO:0023052
GO:0031965
GO:0034340
GO:0042802
GO:0043226
GO:0045071
GO:0045087
GO:0048471
GO:0051607
GO:0070106
GO:0098542
GO:0140374
HMNXSV003034922
ILMN_1662358
M33882_at
PH_hs_0025534
TC21000189.hg
TC21000739.hg
g4505290_3p_at
Participates
as a member of
Mx GTPases [cytosol] (Homo sapiens)
Inferred To
Homologues of MX1 [cytosol]
(Dictyostelium discoideum)
Homologues of MX1 [cytosol]
(Plasmodium falciparum)
MX1 [cytosol]
(Bos taurus)
MX1 [cytosol]
(Dictyostelium discoideum)
MX1 [cytosol]
(Mus musculus)
MX1 [cytosol]
(Plasmodium falciparum)
MX1 [cytosol]
(Rattus norvegicus)
MX1 [cytosol]
(Sus scrofa)
Cross References
RefSeq
NP_002453.2
,
XP_005261038.1
,
XP_016883839.1
,
XP_011527870.1
,
XP_005261035.1
,
NP_001171517.1
,
NP_001269849.1
,
XP_005261037.1
,
XP_005261036.1
,
XP_005261039.1
,
XP_016883838.1
,
NP_001138397.1
OpenTargets
ENSG00000157601
HPA
ENSG00000157601-MX1
GeneCards
P20591
Ensembl
ENSP00000506395
,
ENSP00000505874
,
ENST00000680364
,
ENST00000681896
,
ENST00000680176
,
ENST00000681857
,
ENSP00000506270
,
ENSP00000410523
,
ENST00000680776
,
ENSP00000505630
,
ENSP00000505029
,
ENSP00000408498
,
ENSP00000505189
,
ENSP00000392151
,
ENST00000619682
,
ENST00000417963
,
ENSP00000506183
,
ENST00000681849
,
ENSP00000506199
,
ENSP00000381601
,
ENSP00000505657
,
ENST00000413778
,
ENSP00000506690
,
ENSP00000505457
,
ENSP00000381599
,
ENSP00000505669
,
ENST00000679705
,
ENSP00000506481
,
ENST00000681191
,
ENST00000680347
,
ENST00000679445
,
ENST00000681415
,
ENST00000680760
,
ENST00000455164
,
ENSP00000478441
,
ENST00000681266
,
ENSP00000506047
,
ENST00000419044
,
ENSP00000506220
,
ENSP00000506512
,
ENSP00000506712
,
ENSP00000505781
,
ENST00000679464
,
ENST00000681607
,
ENST00000398598
,
ENST00000679543
,
ENSP00000505051
,
ENSP00000506062
,
ENST00000681867
,
ENSP00000506372
,
ENST00000680629
,
ENSG00000157601
,
ENSP00000506348
,
ENST00000679911
,
ENST00000398600
,
ENST00000679626
,
ENSP00000402215
,
ENSP00000505047
,
ENST00000680536
,
ENSP00000505489
,
ENST00000681039
,
ENST00000680182
,
ENST00000681671
PRO
P20591
Pharos - Targets
P20591
PDB
3LJB
,
4P4S
,
3ZYS
,
4P4U
,
5GTM
,
4P4T
,
3SZR
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q8IUQ4 SIAH1
1
SIAH1 [cytosol]
(R-HSA-374563)
0.556
3
UniProt:O75928-2 PIAS2
1
PIAS2-2 [nucleoplasm]
(R-HSA-2993779)
0.556
3
UniProt:Q13507 TRPC3
1
TRPC3(1-848) [plasma membrane]
(R-HSA-426172)
0.524
2
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