Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Contributors
Papers Citing Us
Resources Guide
Collaboration
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Contributors
Papers Citing Us
Resources Guide
Collaboration
Download
Search ...
Go!
p-S445,T599,T602,S729 B-Raf complex [cytosol]
Stable Identifier
R-HSA-9610128
Type
Complex
Species
Homo sapiens
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by Receptor Tyrosine Kinases (Homo sapiens)
Signaling by NTRKs (Homo sapiens)
Signaling by NTRK1 (TRKA) (Homo sapiens)
Signalling to ERKs (Homo sapiens)
Prolonged ERK activation events (Homo sapiens)
Frs2-mediated activation (Homo sapiens)
Activated BRAF phosphorylates MAP2K dimers downstream of RAP1 and NGF (Homo sapiens)
RAP1:GTP:activated BRAF dimer:MAPK2K:MAPK complex [endosome membrane] (Homo sapiens)
RAP1:GTP:activated BRAF dimer [endosome membrane] (Homo sapiens)
p-S445,T599,T602,S729 B-Raf complex [cytosol] (Homo sapiens)
RAP1:GTP:activated BRAF dimer:p-2S MAPK2K:MAPK complex [endosome membrane] (Homo sapiens)
RAP1:GTP:activated BRAF dimer [endosome membrane] (Homo sapiens)
p-S445,T599,T602,S729 B-Raf complex [cytosol] (Homo sapiens)
Activated BRAF recruits MAP2Ks and MAPKs to the endosome (Homo sapiens)
RAP1:GTP:activated BRAF dimer [endosome membrane] (Homo sapiens)
p-S445,T599,T602,S729 B-Raf complex [cytosol] (Homo sapiens)
RAP1:GTP:activated BRAF dimer:MAPK2K:MAPK complex [endosome membrane] (Homo sapiens)
RAP1:GTP:activated BRAF dimer [endosome membrane] (Homo sapiens)
p-S445,T599,T602,S729 B-Raf complex [cytosol] (Homo sapiens)
BRAF autophosphorylates downstream of RAP1 and NGF (Homo sapiens)
RAP1:GTP:activated BRAF dimer [endosome membrane] (Homo sapiens)
p-S445,T599,T602,S729 B-Raf complex [cytosol] (Homo sapiens)
Dissociation of phosphorylated MAP2Ks and MAPKs (Homo sapiens)
RAP1:GTP:activated BRAF dimer [endosome membrane] (Homo sapiens)
p-S445,T599,T602,S729 B-Raf complex [cytosol] (Homo sapiens)
RAP1:GTP:activated BRAF dimer:p-2S MAPK2K:p-T,Y MAPK complex [endosome membrane] (Homo sapiens)
RAP1:GTP:activated BRAF dimer [endosome membrane] (Homo sapiens)
p-S445,T599,T602,S729 B-Raf complex [cytosol] (Homo sapiens)
MAP2Ks phosphorylate MAPKs downstream of BRAF and NGF (Homo sapiens)
RAP1:GTP:activated BRAF dimer:p-2S MAPK2K:MAPK complex [endosome membrane] (Homo sapiens)
RAP1:GTP:activated BRAF dimer [endosome membrane] (Homo sapiens)
p-S445,T599,T602,S729 B-Raf complex [cytosol] (Homo sapiens)
RAP1:GTP:activated BRAF dimer:p-2S MAPK2K:p-T,Y MAPK complex [endosome membrane] (Homo sapiens)
RAP1:GTP:activated BRAF dimer [endosome membrane] (Homo sapiens)
p-S445,T599,T602,S729 B-Raf complex [cytosol] (Homo sapiens)
Participants
components
p-S446,T599,S602,S729 BRAF [cytosol]
(Homo sapiens)
YWHAB [cytosol]
(Homo sapiens)
x 2
Zn2+ [cytosol]
Participates
as a component of
RAP1:GTP:activated BRAF dimer [endosome membrane] (Homo sapiens)
Inferred To
p-S445,T599,T602,S729 B-Raf complex [cytosol]
(Bos taurus)
p-S445,T599,T602,S729 B-Raf complex [cytosol]
(Caenorhabditis elegans)
p-S445,T599,T602,S729 B-Raf complex [cytosol]
(Danio rerio)
p-S445,T599,T602,S729 B-Raf complex [cytosol]
(Drosophila melanogaster)
p-S445,T599,T602,S729 B-Raf complex [cytosol]
(Gallus gallus)
p-S445,T599,T602,S729 B-Raf complex [cytosol]
(Mus musculus)
p-S445,T599,T602,S729 B-Raf complex [cytosol]
(Rattus norvegicus)
p-S445,T599,T602,S729 B-Raf complex [cytosol]
(Sus scrofa)
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text
