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POU3F2 [nucleoplasm]
Stable Identifier
R-HSA-9613754
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
POU domain, class 3, transcription factor 2, PO3F2_HUMAN
Locations in the PathwayBrowser for interactor UniProt:P56693 SOX10
Expand all
Developmental Biology (Homo sapiens)
MITF-M-regulated melanocyte development (Homo sapiens)
MITF-M-dependent gene expression (Homo sapiens)
Regulation of MITF-M-dependent genes involved in apoptosis (Homo sapiens)
miR-211 represses POU3F2 mRNA translation (Homo sapiens)
POU3F2 [nucleoplasm] (Homo sapiens)
Transcriptional and post-translational regulation of MITF-M expression and activity (Homo sapiens)
POU3F2 binds the MITF promoter (Homo sapiens)
POU3F2 [nucleoplasm] (Homo sapiens)
Nervous system development (Homo sapiens)
EGR2 and SOX10-mediated initiation of Schwann cell myelination (Homo sapiens)
SOX10, POU3F1 and POU3F2 bind EGR2 gene (Homo sapiens)
POU3F2 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:P20265 POU3F2
Gene Names
POU3F2, BRN2, OCT7, OTF7
Chain
chain:1-443
Reference Genes
BioGPS Gene:5454 POU3F2
COSMIC (genes):POU3F2 POU3F2
CTD Gene:5454 POU3F2
dbSNP Gene:5454 POU3F2
ENSEMBL:ENSG00000184486 POU3F2
ENSEMBL_homo_sapiens_GENE:ENSG00000184486.10 POU3F2
HGNC:9215 POU3F2
KEGG Gene (Homo sapiens):5454 POU3F2
Monarch:5454 POU3F2
NCBI Gene:5454 POU3F2
OMIM:600494 POU3F2
UCSC:P20265 POU3F2
Reference Transcript
RefSeq:NM_005604.3 POU3F2
Other Identifiers
11733520_at
17011175
207084_PM_at
207084_at
242455_PM_at
242455_at
2918399
2918400
2918401
2918402
2918403
2918404
2918405
2918406
2918407
2918408
2918409
2918410
2918411
2918412
2918413
2918414
2918420
2918422
2918424
2918426
32327_at
5454
8121209
83248_at
A_14_P102604
A_14_P124529
A_23_P82026
A_33_P3290729
GE658271
GO:0000785
GO:0000978
GO:0000981
GO:0001228
GO:0003677
GO:0003700
GO:0005515
GO:0005634
GO:0005654
GO:0005667
GO:0005694
GO:0006351
GO:0006355
GO:0006357
GO:0007399
GO:0007420
GO:0008284
GO:0008544
GO:0010629
GO:0014044
GO:0021799
GO:0021869
GO:0021897
GO:0021979
GO:0021985
GO:0022011
GO:0030154
GO:0030182
GO:0040018
GO:0042802
GO:0043226
GO:0043565
GO:0045595
GO:0045944
GO:0048663
GO:0048665
GO:0048666
GO:0048856
GO:0048870
GO:0050770
GO:0061101
GO:0071310
GO:0140110
GO:1990837
HMNXSV003027071
Hs.175373.0.A1_3p_at
ILMN_1725772
ILMN_2209045
L37868_s_at
PH_hs_0032041
TC06000828.hg
Z11933_at
g5031982_3p_at
Participates
as a component of
POU3F2:MITF gene [nucleoplasm] (Homo sapiens)
EGR2 gene:POU3F1:POU3F2:SOX10 [nucleoplasm] (Homo sapiens)
as an input of
POU3F2 binds the MITF promoter (Homo sapiens)
SOX10, POU3F1 and POU3F2 bind EGR2 gene (Homo sapiens)
as an output of
miR-211 represses POU3F2 mRNA translation (Homo sapiens)
Inferred To
vvl [nucleoplasm]
(Drosophila melanogaster)
ceh-6 [nucleoplasm]
(Caenorhabditis elegans)
Pou3f2 [nucleoplasm]
(Mus musculus)
Pou3f2 [nucleoplasm]
(Rattus norvegicus)
pou3f2 [nucleoplasm]
(Danio rerio)
pou3f2 [nucleoplasm]
(Xenopus tropicalis)
POU3F1 [nucleoplasm]
(Gallus gallus)
POU3F2 [nucleoplasm]
(Bos taurus)
POU3F2 [nucleoplasm]
(Canis familiaris)
POU3F2 [nucleoplasm]
(Sus scrofa)
Cross References
RefSeq
NP_005595.2
OpenTargets
ENSG00000184486
HPA
ENSG00000184486-POU3F2
GeneCards
P20265
Ensembl
ENST00000328345
,
ENSP00000329170
,
ENSG00000184486
PRO
P20265
Pharos - Targets
P20265
PDB
7XRC
Interactors (5)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q09472 EP300
5
monoSUMO1-K1020,1024-EP300 [nucleoplasm]
(R-HSA-3899306)
Foxo4-S-S-EP300 [nucleoplasm]
(R-HSA-9617720)
FOXO4-S-S-EP300 [nucleoplasm]
(R-HSA-9617691)
p-S,T-EP300 [nucleoplasm]
(R-HSA-8878072)
EP300 [nucleoplasm]
(R-HSA-381325)
0.602
3
UniProt:P20265 POU3F2
1
POU3F2 [nucleoplasm]
(R-HSA-9613754)
0.527
2
UniProt:P20226 TBP
1
TBP [nucleoplasm]
(R-HSA-83718)
0.527
2
UniProt:P56693 SOX10
2
SOX10 [nucleoplasm]
(R-HSA-9613639)
p-T240,T244-SOX10 [nucleoplasm]
(R-HSA-9824578)
0.527
3
UniProt:P23760 PAX3
2
PAX3 [nucleoplasm]
(R-HSA-9757859)
PAX3 (1-319) [nucleoplasm]
(R-HSA-5603237)
0.527
2
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