PLXNA4 gene expression is stimulated by FOXO6

Stable Identifier
R-HSA-9615023
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
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PLXNA4 gene expression is stimulated by FOXO6
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Based on studies in mice, FOXO6 directly stimulates transcription of the semaphorin SEMA3A co-receptor PLXNA4 (Plexin A4). Defects in migration of the radial glia during cortical development observed in Foxo6 knockout mice can be restored by ectopic overexpression of Plxna4 (Paap et al. 2016).
Participants
Input
Output
Participates
as an event of
This event is regulated
Positively by
Regulator
FOXO6:PLXNA4 gene [nucleoplasm] (Homo sapiens)
Active Unit
FOXO6 [nucleoplasm]
Inferred From
Plxna4 gene expression is stimulated by Foxo6 (Mus musculus)
Authored
Orlic-Milacic, M  (2018-10-11)
Reviewed
Bertaggia, E  (2018-10-26)
Donlon, T  (2018-10-17)
Created
Orlic-Milacic, M  (2018-07-30)
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