Late endosomal microautophagy

Stable Identifier
R-HSA-9615710
DOI
10.3180/R-HSA-9615710.1
Type
Pathway
Species
Homo sapiens
Compartment
cytosol, phagocytic vesicle
ReviewStatus
5/5
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Late endosomal microautophagy
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Microautophagy (MI) is a non-selective autophagic pathway that involves internalisation of cytosolic cargo through invaginations of the lysosomal membrane. MI can be induced by nitrogen starvation and complements other related self-eating processes such as Macroautophagy (MA) and Chaperone Mediated Autophagy (CMA). MI can degrade cell organelles and bulk cytosolic proteins directly via the lysosome and late endosome. MI can also target substrates with KFERQ motifs with the help of HSPA8 (Li W W et al. 2012).
Literature References
PubMed ID Title Journal Year
22080117 Microautophagy: lesser-known self-eating

Li, WW, Bao, JK, Li, J

Cell. Mol. Life Sci. 2012
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Events
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as an event of
Event Information
Go Biological Process
late endosomal microautophagy (0061738)
Cross References
BioModels Database
Authored
Varusai, TM  (2019-02-21)
Reviewed
Metzakopian, E  (2019-02-22)
Created
Varusai, TM  (2018-08-08)
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