Reactome | RAN:GTP recruits nuclear envelope (NE) membranes

RAN:GTP recruits nuclear envelope (NE) membranes

Stable Identifier

R-HSA-9624876

Type

Reaction [binding]

Species

Homo sapiens

Compartment

cytosol

ReviewStatus

5/5

Locations in the PathwayBrowser

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Cell Cycle (Homo sapiens)

- Cell Cycle, Mitotic (Homo sapiens)
  - M Phase (Homo sapiens)
    - Mitotic Metaphase and Anaphase (Homo sapiens)
      - Mitotic Anaphase (Homo sapiens)
        
        Nuclear Envelope (NE) Reassembly (Homo sapiens)
        
        Postmitotic nuclear pore complex (NPC) reformation (Homo sapiens)
        
        RAN:GTP recruits nuclear envelope (NE) membranes (Homo sapiens)

General

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RAN:GTP recruits nuclear envelope (NE) membranes

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RAN:GTP is required for recruitment of membrane vesicles to chromatin during NE reassembly with an in vitro system (Zhang and Clarke 2001). This process could involve actions of RAN:GTP on many targets (reviewed by Forbes et al. 2015).

Literature References

PubMed ID	Title	Journal	Year
11231159	Roles of Ran-GTP and Ran-GDP in precursor vesicle recruitment and fusion during nuclear envelope assembly in a human cell-free system Clarke, PR, Zhang, C	Curr. Biol.	2001